The participation of annexin II (calpactin I) in calcium-evoked exocytosis requires protein kinase C.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

NUCLEOSIDE PHOSPHOROTHIOATES

1985 • 830 citations

Characterization of microcystin-LR, a potent inhibitor of type 1 and type 2A protein phosphatases.

1990 • 589 citations

Identity of p36K phosphorylated upon Rous sarcoma virus transformation with a protein purified from brush borders; calcium-dependent binding to non-erythroid spectrin and F-actin.

1984 • 541 citations

Aggregation of chromaffin granules by calpactin at micromolar levels of calcium

1988 • 443 citations

A role for calpactin in calcium-dependent exocytosis in adrenal chromaffin cells

1989 • 321 citations

Inhibition of phorbol ester-dependent differentiation of human promyelocytic leukemic (HL-60) cells by sphinganine and other long-chain bases.

1986 • 307 citations

Characterization of Ca2+-dependent phospholipid binding, vesicle aggregation and membrane fusion by annexins

1990 • 293 citations

The annexin family of calcium-binding proteins

1989 • 287 citations

Calpactins: two distinct Ca++-regulated phospholipid- and actin-binding proteins isolated from lung and placenta.

1987 • 275 citations

Amino-terminal sequence of p36 and associated p10: identification of the site of tyrosine phosphorylation and homology with S-100.

1985 • 268 citations

The Cytoskeleton as a Barrier to Exocytosis in Secretory Cells

1988 • 259 citations

Calcium control of exocytosis and endocytosis in bovine adrenal medullary cells

1981 • 250 citations

The protein-tyrosine kinase substrate p36 is also a substrate for protein kinase C in vitro and in vivo.

1986 • 204 citations

Calcium-dependent conformational changes in the 36-kDa subunit of intestinal protein I related to the cellular 36-kDa target of Rous sarcoma virus tyrosine kinase.

1985 • 200 citations

Long-term phorbol ester treatment down-regulates protein kinase C and sensitizes the phosphoinositide signaling pathway to hormone and growth factor stimulation. Evidence for a role of protein kinase C in agonist-induced desensitization.

1988 • 186 citations

Regulation of calpactin I phospholipid binding by calpactin I light-chain binding and phosphorylation by p60v-src

1987 • 184 citations

Characterization of the chromobindins. Soluble proteins that bind to the chromaffin granule membrane in the presence of Ca2+.

1983 • 180 citations

Conformational change and localization of calpactin I complex involved in exocytosis as revealed by quick-freeze, deep-etch electron microscopy and immunocytochemistry.

1990 • 179 citations

Identification of chromaffin granule-binding proteins. Relationship of the chromobindins to calelectrin, synhibin, and the tyrosine kinase substrates p35 and p36.

1987 • 175 citations

Purified rat brain calcium- and phospholipid-dependent protein kinase phosphorylates ribosomal protein S6.

1983 • 160 citations

Sphingosine inhibition of agonist-dependent secretion and activation of human platelets implies that protein kinase C is a necessary and common event of the signal transduction pathways.

1987 • 156 citations

Characterization of hormone and protein release from alpha-toxin-permeabilized chromaffin cells in primary culture.

1986 • 147 citations

Protein Kinase C Located in Rat Liver Nuclei

1989 • 145 citations

A 42-kD tyrosine kinase substrate linked to chromaffin cell secretion exhibits an associated MAP kinase activity and is highly related to a 42-kD mitogen-stimulated protein in fibroblasts.

1990 • 142 citations

Protein kinase C catalyzes phosphorylation of guanylate cyclase in vitro.

1985 • 140 citations

Peripheral actin filaments control calcium-mediated catecholamine release from streptolysin-O-permeabilized chromaffin cells.

1988 • 137 citations

Effects of phorbol esters, diglyceride, and cholinergic agonists on the subcellular distribution of protein kinase C in intact or digitonin-permeabilized adrenal chromaffin cells.

1986 • 134 citations

Primary structure of human placental anticoagulant protein

1987 • 132 citations

Loss of proteins from digitonin-permeabilized adrenal chromaffin cells essential for exocytosis.

1987 • 124 citations

Annexins—New family of Ca2+-regulated-phospholipid binding protein

1987 • 117 citations

Thermodynamic Parameters for the Hydrolysis of Inorganic Pyrophosphate at pH 7.4 as a Function of [Mg2+], [K+], and Ionic Strength Determined from Equilibrium Studies of the Reaction

1974 • 116 citations

Binding sites for calcium, lipid and p11 on p36, the substrate of retroviral tyrosine‐specific protein kinases

1986 • 112 citations

Three Ca2+-binding proteins from porcine liver and intestine differ immunologically and physicochemically and are distinct in Ca2+ affinities.

1985 • 111 citations

p60c-src activity detected in the chromaffin granule membrane

1986 • 109 citations

Human 67-kDa calelectrin contains a duplication of four repeats found in 35-kDa lipocortins.

1988 • 109 citations

Biochemical characterization of a 34-kilodalton normal cellular substrate of pp60v-src and an associated 6-kilodalton protein.

1984 • 100 citations

Association of the S-100-related calpactin I light chain with the NH2-terminal tail of the 36-kDa heavy chain.

1986 • 98 citations

Protein phosphorylation and secretion in digitonin-permeabilized adrenal chromaffin cells. Effects of micromolar Ca2+, phorbol esters, and diacylglycerol.

1986 • 85 citations

A re-assessment of the role of protein kinase C in glucose-stimulated insulin secretion

1987 • 77 citations

Secretory cell actin-binding proteins: identification of a gelsolin-like protein in chromaffin cells.

1986 • 75 citations

Phosphorylation of lipocortins invitro by protein kinase C

1986 • 75 citations

p60c-src is complexed with a cellular protein in subcellular compartments involved in exocytosis.

1988 • 69 citations

A reassessment of Guanine Nucleotide Effects on Catecholamine Secretion from Permeabilized Adrenal Chromaffin cells

1989 • 58 citations

Differential Subcellular Distribution of p36 (the Heavy Chain of Calpactin I) and Other Annexins in the Adrenal Medulla

1991 • 48 citations

The stimulatory effect of calpactin (annexin II) on calcium-dependent exocytosis in chromaffin cells: Requirement for both the N-terminal and core domains of p36 and ATP

1990 • 45 citations

The Protein-Tyrosine Kinase Substrate p36 Is Also a Substrate for Protein Kinase C In Vitro and In Vivo

1986 • 44 citations

Effect of secretagogues on chromogranin A synthesis in bovine cultured chromaffin cells. Possible regulation by protein kinase C

1989 • 31 citations

Biochemical Characterization of Annexins I and II Isolated from Pig Nervous Tissue

1991 • 28 citations

Biochemical Characterization of a 34-Kilodalton Normal Cellular Substrate of pp60^v-src and an Associated 6-Kilodalton Protein

1984 • 26 citations

[Isolation of Ca2+ sensitive proteins linked to the membrane fraction of the brain cortex and the spinal cord in pigs].

1989 • 1 citations