Effect of secretagogues on chromogranin A synthesis in bovine cultured chromaffin cells. Possible regulation by protein kinase C

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Secretion of a Chromaffin Granule Protein, Chromogranin, from the Adrenal Gland after Splanchnic Stimulation

1967 • 523 citations

Calcium-dependence of catecholamine release from bovine adrenal medullary cells after exposure to intense electric fields

1982 • 500 citations

Opiate-like materials in the adrenal medulla: evidence for storage and secretion with catecholamines.

1979 • 492 citations

The composition of adrenal chromaffin granules: An assessment of controversial results

1976 • 435 citations

The molecular function of adrenal chromaffin granules: Established facts and unresolved topics

1986 • 358 citations

Bovine chromogranin A sequence and distribution of its messenger RNA in endocrine tissues

1986 • 314 citations

Co-release of enkephalin and catecholamines from cultured adrenal chromaffin cells

1981 • 301 citations

The phorbol ester TPA increases the affinity of exocytosis for calcium in ‘leaky’ adrenal medullary cells

1983 • 269 citations

The primary structure of bovine chromogranin A: a representative of a class of acidic secretory proteins common to a variety of peptidergic cells.

1986 • 253 citations

Calcium-evoked secretion from digitonin-permeabilized adrenal medullary chromaffin cells.

1983 • 247 citations

Chromogranin A: Immunohistology reveals its universal occurrence in normal polypeptide hormone producing endocrine glands

1983 • 243 citations

Protein kinase C activation in mixed micelles. Mechanistic implications of phospholipid, diacylglycerol, and calcium interdependencies.

1986 • 217 citations

Nicotinic receptor stimulation activates enkephalin release and biosynthesis in adrenal chromaffin cells

1984 • 210 citations

Secretion from chromaffin cells is controlled by chromogranin A-derived peptides.

1988 • 193 citations

Chromogranin immunoreactivity in the central nervous system. Immunochemical characterisation, distribution and relationship to catecholamine and enkephalin pathways

1984 • 193 citations

Phosphorylation and activation of tyrosine hydroxylase mediate the cAMP-induced increase in catecholamine biosynthesis in adrenal chromaffin cells.

1982 • 177 citations

Similarity of secretory protein I from parathyroid gland to chromogranin A from adrenal medulla.

1982 • 171 citations

Characterization of hormone and protein release from alpha-toxin-permeabilized chromaffin cells in primary culture.

1986 • 147 citations

Neurons and neuroendocrine cells contain chromogranin: detection of the molecule in normal bovine tissues by immunochemical and immunohistochemical methods.

1985 • 145 citations

Neural and humoral factors separately regulate neuropeptide Y, enkephalin, and chromogranin A and B mRNA levels in rat adrenal medulla.

1988 • 140 citations

Protein kinase C catalyzes phosphorylation of guanylate cyclase in vitro.

1985 • 140 citations

Alternative modes of enkephalin biosynthesis regulation by reserpine and cyclic AMP in cultured chromaffin cells.

1984 • 134 citations

Effects of phorbol esters, diglyceride, and cholinergic agonists on the subcellular distribution of protein kinase C in intact or digitonin-permeabilized adrenal chromaffin cells.

1986 • 134 citations

Chromogranin A, B, and C in human adrenal medulla and endocrine tissues.

1986 • 132 citations

Rat adrenal medulla: Levels of chromogranins, enkephalins, dopamine β-hydroxylase and of the amine transporter are changed by nervous activity and hypophysectomy

1987 • 131 citations

Phorbol ester binding and activation of protein kinase C on triton X-100 mixed micelles containing phosphatidylserine.

1986 • 127 citations

Chromogranin A in the pancreatic islet: cellular and subcellular distribution.

1986 • 115 citations

Calcium mobilization and catecholamine secretion in adrenal chromaffin cells. A Quin-2 fluorescence study.

1986 • 112 citations

Muscarinic receptors on bovine chromaffin cells mediate a rise in cytosolic calcium that is independent of extracellular calcium.

1985 • 109 citations

Chromaffin cell calcium channel kinetics measured isotopically through fast calcium, strontium, and barium fluxes.

1987 • 108 citations

Chromogranin A (CGA) in the gastro-entero-pancreatic (GEP) endocrine system

1986 • 99 citations

Characterization of protein kinase C and its role in catecholamine secretion from bovine adrenal-medullary cells

1985 • 80 citations

A re-assessment of the role of protein kinase C in glucose-stimulated insulin secretion

1987 • 77 citations

Cyclic adenosine monophosphate regulates vasoactive intestinal polypeptide and enkephalin biosynthesis in cultured bovine chromaffin cells

1983 • 76 citations

Biosynthesis of betagranin in pancreatic β-cells. Identification of a chromogranin A-like precursor and its parallel processing with proinsulin

1987 • 76 citations

Cell-free and cellular synthesis of chromogranin A and B of bovine adrenal medulla

1985 • 75 citations

Immunocytochemical Study of Microtubules in Chromaffin Cells in Culture and Evidence That Tubulin Is Not an Integral Protein of the Chromaffin Granule Membrane

1981 • 75 citations

Multiple regulation of proenkephalin gene expression by protein kinase C.

1988 • 65 citations

Chromogranin A and B and Secretogranin II in Medullary Carcinomas of the Thyroid

1987 • 63 citations

Regulation of Enkephalin, VIP, and Chromogranin Biosynthesis in Actively Secreting Chromaffin Cells

1987 • 59 citations

Cholinergic regulation of protein phosphorylation in bovine adrenal chromaffin cells.

1988 • 48 citations

Biosynthetic relationship between the major matrix proteins of adrenal chromaffin granules

1983 • 44 citations

Chromogranin A Synthesis and Secretion in Chromaffin Cells

1987 • 38 citations

Chromogranin A is present in and released by fish endocrine tissue

1987 • 32 citations

The Coregulation of Secretion and Cytoplasmic Ribonucleic Acid of Chromogranin-A and Calcitonin by Phorbol Ester in Cells That Produce Both Substances*

1988 • 25 citations

Phorbol ester stimulates catecholamine synthesis in isolated bovine adrenal medullary cells

1985 • 25 citations

Neurofilament Proteins in Cultured Chromaffin Cells

1984 • 24 citations