G Protein Activation of a Hormone-Stimulated Phosphatase in Human Tumor Cells

Cyanobacterial microcystin‐LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants

1990 • 1,627 citations

Two G Protein Oncogenes in Human Endocrine Tumors

1990 • 1,038 citations

Protein Tyrosine Phosphatases: A Diverse Family of Intracellular and Transmembrane Enzymes

1991 • 973 citations

A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles.

1982 • 788 citations

Inhibition of membrane phosphotyrosyl-protein phosphatase activity by vanadate

1982 • 699 citations

Human pancreatic carcinoma (mia paca‐2) in continuous culture: Sensitivity to asparaginase

1977 • 364 citations

Transformation of cells by an inhibitor of phosphatases acting on phosphotyrosine in proteins

1985 • 331 citations

Dephosphorylation of cAMP-dependent protein kinase regulatory subunit (type II) by calmodulin-dependent protein phosphatase. Determinants of substrate specificity.

1986 • 187 citations

Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation in intact Swiss 3T3 cells.

1991 • 156 citations

Microinjection of a protein-tyrosine-phosphatase inhibits insulin action in Xenopus oocytes.

1990 • 151 citations

Stimulation by somatostatin of dephosphorylation of membrane proteins in pancreatic cancer MIA PaCa‐2 cell line

1985 • 138 citations

Activating and inactivating mutations of the alpha subunit of Gi2 protein have opposite effects on proliferation of NIH 3T3 cells.

1991 • 110 citations

Receptor for bombesin with associated tyrosine kinase activity.

1986 • 77 citations

The epidermal growth factor receptor is coupled to a phospholipase A2-specific pertussis toxin-inhibitable guanine nucleotide-binding regulatory protein in cultured rat inner medullary collecting tubule cells.

1990 • 71 citations

Regulation of luteinizing hormone-releasing hormone receptor binding by heterologous and autologous receptor-stimulated tyrosine phosphorylation.

1991 • 52 citations

[37] Purification of protein-tyrosine phosphatases from human placenta

1991 • 44 citations

Phosphotyrosyl-protein phosphatases

1989 • 26 citations

Regulation of luteinizing hormone-releasing hormone receptor binding by heterologous receptorstimulated tyrosine phosphorylation

1991 • 22 citations

Expression of a G protein subunit, alpha i-1, in Balb/c 3T3 cells leads to agonist-specific changes in growth regulation.

1991 • 22 citations