Antioxidant activity and other mechanisms of thiols involved in chemoprevention of mutation and cancer

Chemoprevention of Cancer

2008 • 1,269 citations

SYSTEMIC GLUTATHIONE DEFICIENCY IN SYMPTOM-FREE HIV-SEROPOSITIVE INDIVIDUALS

1989 • 725 citations

[Chemoprevention of cancer].

1986 • 524 citations

Inhibitors of endogenous nitrosation mechanisms and implications in human cancer prevention

1988 • 297 citations

Chemical carcinogens and DNA

1979 • 288 citations

Lung Protection by a Thiol-Containing Antioxidant: N-Acetylcysteine

1986 • 266 citations

Mutagens and Carcinogens in the Diet

1991 • 239 citations

Chemical Carcinogenesis and Mutagenesis I

1990 • 225 citations

Regression and persistence of hyperplastic hepatic nodules induced by N-2-Fluorenylacetamide and their relationship to hepatocarcinogenesis.

1971 • 221 citations

Anticarcinogenesis and Radiation Protection

1987 • 210 citations

Nutritional and Toxicological Significance of Enzyme Inhibitors in Foods

1986 • 167 citations

³²P-adduct assay: comparative recoveries of structurally diverse DNA adducts in the various enhancement procedures

1988 • 163 citations

Inhibitors of mutagenesis and their relevance to carcinogenesis

1986 • 156 citations

In vivo effects of N-acetylcysteine on glutathione metabolism and on the biotransformation of carcinogenic and/or mutagenic compounds

1985 • 152 citations

Inhibitors of chemical carcinogens.

1980 • 152 citations

Mutation and the environment

1990 • 148 citations

Metabolic deactivation of mutagens in the Salmonella-microsome test

1978 • 118 citations

An applied synchronous fluorescence spectrophotometric assay to study benzo[a]pyrene-diolepoxide-DNA adducts

1985 • 117 citations

Naturally Occurring Anticarcinogenic Substances in Foodstuffs

1985 • 114 citations

Inhibition of urethan-induced lung tumors in mice by dietary N-acetylcysteine

1986 • 104 citations

Inhibitory effects of glutathione level-raising agents and D-α-tocopherol on ornithine decarboxylase induction and mouse skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate

1985 • 102 citations

In vitro effects of N-acetylcysteine on the mutagenicity of direct-acting compounds and procarcinogens

1984 • 82 citations

Medicine and the Law

1961 • 66 citations

Pure exogenous singlet oxygen: Nonmutagenicity in bacteria

1988 • 53 citations

Inhibition of Chemical Carcinogenesis

1990 • 47 citations

Anti-initiation activity of N-acetylcysteine in experimental colonic carcinogenesis

1986 • 46 citations

Anticarcinogenic potential of DNA-repair modulators

1988 • 42 citations

Glutathione: A protective agent in Salmonella typhimurium and Escherichia coli as measured by mutagenicity and by growth delay assays

1986 • 40 citations

Mutagenicity of active oxygen species in bacteria and its enzymatic or chemical inhibition

1989 • 38 citations

Depletion of adenosine diphosphate-ribosyl transferase activity in rat liver during exposure to N-2-acetylaminofluorene: effect of thiols.

1988 • 36 citations

Changes in activity and mRNA levels of poly(ADP-ribose) polymerase during rat liver regeneration

1990 • 33 citations

Detoxifying activities in alveolar macrophages of rats treated with acetylcysteine, diethyl maleate and/or aroclor.

1986 • 31 citations

Problems and prospects in antimutagenesis and anticarcinogenesis

1988 • 30 citations

Detoxification of Genotoxic Compounds as a Threshold Mechanism Limiting Their Carcinogenicity

1984 • 29 citations

Chemical Carcinogenesis: Models and Mechanisms

2013 • 27 citations

Nutritional Improvement of Legume Proteins through Disulfide Interchange

1986 • 26 citations

Anticarcinogenesis mechanisms, as evaluated in the multistage mouse skin model

1988 • 24 citations

Mechanism of N-acetylcysteine (NAC) and other thiols as both positive and negative modifiers of MNNG-induced mutagenicity in V79 Chinese hamster cells

1987 • 23 citations

Relationship between poly(ADP-ribose) polymerase activity and DNA synthesis in cultured hepatocytes

1990 • 21 citations

Effects of aminothiols in 2-acetylaminofluorene-treated rats. I. Damage and repair of liver DNA, hyperplastic foci, and Zymbal gland tumors.

1987 • 21 citations

Antimutagenic and Anticarcinogenic Mechanisms of Aminothiols

1991 • 20 citations

Second primary cancers in the lung in head and neck cancer patients: a Challenge

1987 • 20 citations

Chemical Carcinogenesis and Mutagenesis II

1990 • 19 citations

Synopsis of the first international conference on antimutagenesis and anticarcinogenesis: Mechanisms

1987 • 15 citations

Differential assay and biological significance of poly(ADP-ribose) polymerase activity in isolated liver nuclei

1990 • 13 citations

Effects of aminothiols in 2-acetylaminofluorene-treated rats. II. Glutathione cycle and liver cytosolic activities.

1987 • 10 citations

Protection of Nuclear Enzymes by Aminothiols

1991 • 10 citations

Metabolic activation of food hepatocarcinogens in hepatitis B virus-infected humans and animals.

1990 • 9 citations

Development and application of biomarkers exploitable for human exposure monitoring

1990 • 8 citations

Antigenotoxic and Anticarcinogenic Effects of Thiols. In Vitro Inhibition of the Mutagenicity of Drug Nitrosation Products and Protection of Rat Liver ADP-Ribosyl Transferase Activity

1988 • 8 citations

Role of Glutathione and N-Acetylcysteine as Inhibitors of Mutagenesis and Carcinogenesis

2018 • 6 citations

Nucleophiles as Anticarcinogens

1987 • 4 citations

Variations of Glutathione Concentrations and of Cytosolic Enzyme Activities in the Liver of Rats Treated with 2-Acetylaminofluorene and/or N-Acetylcysteine

1991 • 2 citations