Profound loss of T-cell receptor repertoire complexity in cutaneous T-cell lymphoma

Genetic instabilities in human cancers

1998 • 4,165 citations

The multistep nature of cancer

1993 • 1,872 citations

Interaction of Staphylococcus aureus toxin "superantigens" with human T cells.

1989 • 1,000 citations

The Merck Manual of Diagnosis and Therapy

1957 • 998 citations

Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy".

1994 • 788 citations

Maintaining the norm: T-cell homeostasis

2002 • 608 citations

T-cell repertoire diversity and clonal expansions in normal and clinical samples

1995 • 562 citations

Psoriasis: a T-cell-mediated autoimmune disease induced by streptococcal superantigens?

1995 • 368 citations

Expanded CD4+ and CD8+ T cell clones in elderly humans.

1997 • 307 citations

An experimentally validated panel of subfamily‐specific oligonucleotide primers (V_α1‐w29/V_β1‐w24) for the study of human T cell receptor variable V gene segment usage by polymerase chain reaction

1992 • 302 citations

Clinical Stage IA (Limited Patch and Plaque) Mycosis Fungoides

1996 • 278 citations

Association of Erythrodermic Cutaneous T-Cell Lymphoma, Superantigen-Positive Staphylococcus aureus, and Oligoclonal T-Cell Receptor Vβ Gene Expansion

1997 • 253 citations

Increased CCR4 Expression in Cutaneous T Cell Lymphoma

2002 • 248 citations

Profound deletion of mature T cells in vivo by chronic exposure to exogenous superantigen.

1993 • 241 citations

Mycosis fungoides—a disease of antigen persistence

1974 • 241 citations

Infections Complicating Mycosis Fungoides and Sézary Syndrome

1992 • 211 citations

Cutaneous T Cell Lymphoma

2001 • 184 citations

Age-related modifications of the human alphabeta T cell repertoire due to different clonal expansions in the CD4+ and CD8+ subsets

1998 • 172 citations

The extent of the human germline T-cell receptor V beta gene segment repertoire

1994 • 164 citations

Prognostic significance of tumor burden in the blood of patients with erythrodermic primary cutaneous T-cell lymphoma

2001 • 157 citations

Reconstitution of T-cell receptor repertoire diversity following T-cell depleted allogeneic bone marrow transplantation is related to hematopoietic chimerism

2000 • 154 citations

The cutaneous T cell lymphoma, mycosis fungoides, is a human T cell lymphotropic virus-associated disease. A study of 50 patients.

1995 • 149 citations

Clonal heterogeneity in mycosis fungoides and its relationship to clinical course

2002 • 136 citations

The Merck Manual of Diagnosis and Therapy.

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Molecular analysis of T cell repertoires

1995 • 115 citations

T cell repertoire in patients with B chronic lymphocytic leukemia. Evidence for multiple in vivo T cell clonal expansions.

1994 • 114 citations

The Immunopemthogenesis of Cutaneous T-cell Lymphoma

1995 • 108 citations

Effect of recent thymic emigrants on progression of HIV-1 disease

2000 • 101 citations

T cell receptor V beta gene usage in a human alloreactive response. Shared structural features among HLA-B27-specific T cell clones.

1990 • 94 citations

Benign Monoclonal Gammopathy

1982 • 93 citations

Highly restricted human T cell repertoire in peripheral blood and tissue-infiltrating lymphocytes in Omenn's syndrome.

1998 • 90 citations

Pathogenesis of cutaneous T-cell lymphoma: implications for the use of recombinant cytokines and photopheresis.

1997 • 74 citations

Mycosis fungoides and Sezary syndrome are not associated with HTLV‐I infection: an international study

1997 • 65 citations

T-cell receptor gene analysis in the diagnosis of Se ́zary syndrome

1999 • 63 citations

Persistent clonal excess and skewed T-cell repertoire in T cells from patients with hairy cell leukemia

1996 • 58 citations

PCR-based analysis of the T-cell receptor V beta multigene family: experimental parameters affecting its validity.

1992 • 52 citations

Improved Assessment of T-Cell Receptor (TCR) VB Repertoire in Clinical Specimens: Combination of TCR-CDR3 Spectratyping with Flow Cytometry-Based TCR VB Frequency Analysis

2002 • 51 citations

Secondary Malignant Neoplasms in 71 Patients With Sézary Syndrome

1999 • 49 citations

Crosstalk between Tumor T Lymphocytes and Reactive T Lymphocytes in Cutaneous T Cell Lymphomas

2001 • 48 citations

Gene Therapy for Cardiovascular Disorders

2001 • 36 citations

Atlas of Clinical Oncology

2003 • 31 citations

The Repertoire of T Cell Antigen Receptor β-Chain Variable Regions Associated with Psoriasis Vulgaris

1997 • 28 citations

Restriction of T‐cell receptor repertoires in idiopathic CD4⁺ lymphocytopenia

2000 • 20 citations

TCRBV CDR3 diversity of cd4+ and cd8+ t-lymphocytes in HIV-infected individuals

2002 • 12 citations

T CELL RECEPTOR ??-CHAIN REPERTOIRES ARE NONRANDOMLY SELECTED IN RESPONSES TO HLA-DR11

1996 • 11 citations