Induction ofin VitroAngiogenesis in the Endothelial-Derived Cell Line, EA hy926, by Ethanol Is Mediated through PKC and MAPK

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Angiogenic Factors

1987 • 3,702 citations

Angiogenesis.

1992 • 2,581 citations

Inflammation. Basic principles and clinical correlates

1989 • 2,424 citations

The mitogen-activated protein kinase signal transduction pathway

1993 • 2,174 citations

Signal transduction via the MAP kinases: proceed at your own RSK.

1993 • 1,262 citations

Cyclin D1 Expression Is Regulated Positively by the p42/p44 and Negatively by the p38/HOG Pathway

1996 • 1,203 citations

Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation.

1993 • 992 citations

Basic fibroblast growth factor induces angiogenesis in vitro.

1986 • 828 citations

Activation of the Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Pathway by Conventional, Novel, and Atypical Protein Kinase C Isotypes

1998 • 765 citations

Tumor-promoting phorbol esters induce angiogenesis in vitro

1985 • 470 citations

A synthetic peptide substrate for selective assay of protein kinase C

1990 • 292 citations

Plasminogen activator and collagenase production by cultured capillary endothelial cells

1982 • 279 citations

Activation of mitogen-activated protein kinases by vascular endothelial growth factor and basic fibroblast growth factor in capillary endothelial cells is inhibited by the antiangiogenic factor 16-kDa N-terminal fragment of prolactin.

1995 • 231 citations

Co-regulation of the mitogen-activated protein kinase, extracellular signal-regulated kinase 1, and the 90-kDa ribosomal S6 kinase in PC12 cells. Distinct effects of the neurotrophic factor, nerve growth factor, and the mitogenic factor, epidermal growth factor

1993 • 224 citations

In vitro model of angiogenesis using a human endothelium‐derived permanent cell line: Contributions of induced gene expression, G‐proteins, and integrins

1992 • 198 citations

Chronic ethanol exposure increases levels of protein kinase C delta and epsilon and protein kinase C-mediated phosphorylation in cultured neural cells.

1991 • 195 citations

Protein kinase C mediates platelet-derived growth factor-induced tyrosine phosphorylation of p42.

1988 • 166 citations

Endothelium specific Weibel-Palade bodies in a continuous human cell line, EA.hy926

1990 • 119 citations

Induction of mitogen-activated protein kinase signal transduction pathway during gastric ulcer healing in rats

1998 • 96 citations

Ethanol causes desensitization of receptor-mediated phospholipase C activation in isolated hepatocytes

1991 • 91 citations

Human umbilical vein and dermal microvascular endothelial cells show heterogeneity in response to PKC activation

1997 • 89 citations

Ethanol enhances growth factor activation of mitogen-activated protein kinases by a protein kinase C-dependent mechanism.

1995 • 85 citations

Induction of angiogenesis in vitro by vanadate, an inhibitor of phosphotyrosine phosphatases

1988 • 76 citations

Requirement for Protein Kinase C Activation in Basic Fibroblast Growth Factor–Induced Human Endothelial Cell Proliferation

1995 • 74 citations

REGULATION AND ROLE OF UROKINASE PLASMINOGEN ACTIVATOR IN VASCULAR REMODELLING

1996 • 57 citations

Distorted microangioarchitecture and impaired angiogenesis in gastric mucosa of portal hypertensive rats

1994 • 45 citations

Ethanol Exposure Increases Total Protein Kinase C Activity in Human Lymphocytes

1993 • 43 citations

Role of Protein Kinase C in Attachment, Spreading, and Migration of Human Endothelial Cells

1996 • 43 citations

Helicobacter pylori culture supernatant interferes with epidermal growth factor-activated signal transduction in human gastric KATO III cells.

1998 • 38 citations

Induction of the c-jun proto-oncogene by a protein kinase c-dependent mechanism during exposure of human epidermal keratinocytes to ethanol

1993 • 37 citations

Effects of Ethanol on Phospholipases in the Mouse Brain, Heart and Liver.

1996 • 8 citations

Effects of Ethanol on Phosphorylation of Lipids in Rat Synaptic Plasma Membranes

1996 • 6 citations