Effect of inhibitors of Na⁺/H⁺‐exchange and gastric H⁺/K⁺ ATPase on cell volume, intracellular pH and migration of human polymorphonuclear leucocytes

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Cleavage of structural proteins during the assemble of the head of bacterio-phage T4

1970 • 5,738 citations

Functional Significance of Cell Volume Regulatory Mechanisms

1998 • 1,871 citations

On the Crawling of Animal Cells

1993 • 1,020 citations

Neutrophil activation on biological surfaces. Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes.

1987 • 823 citations

Na+/H+ exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation

1989 • 749 citations

Molecular physiology of vertebrate Na+/H+ exchangers

1997 • 624 citations

Cortical Flow in Animal Cells

1988 • 554 citations

Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion

1995 • 413 citations

Hormonal regulation, pharmacology, and membrane sorting of vertebrate Na+/H+ exchanger isoforms

1995 • 394 citations

The Pharmacology of the Gastric Acid Pump: The H+,K+ ATPase

1995 • 358 citations

The Directed Migration of Eukaryotic Cells

1986 • 312 citations

Arginine vasopressin enhances pHi regulation in the presence of HCO−3 by stimulating three acid-base transport systems

1989 • 269 citations

Pharmacological characterization of stably transfected Na+/H+ antiporter isoforms using amiloride analogs and a new inhibitor exhibiting anti-ischemic properties.

1993 • 245 citations

Use of fluorescent dyes in the determination of adherence of human leucocytes to endothelial cells and the effect of fluorochromes on cellular function

1994 • 241 citations

Activation of the Na+/H+ antiporter during cell volume regulation. Evidence for a phosphorylation-independent mechanism.

1992 • 223 citations

Changes in membrane potential of human granulocytes antecede the metabolic responses to surface stimulation

1978 • 218 citations

Sensory adaptation of leukocytes to chemotactic peptides.

1979 • 190 citations

The Physics of Cell Motility

1987 • 190 citations

Focal localization of the NHE-1 isoform of the Na+/H+ antiport: assessment of effects on intracellular pH.

1993 • 189 citations

Effects of omeprazole on neutrophil chemotaxis, super oxide production, degranulation, and translocation of cytochrome b-245.

1992 • 179 citations

Hoe 694, a new Na+/H⁺ exchange inhibitor and its effects in cardiac ischaemia

1993 • 179 citations

The Mechanism and Structure of the Gastric H, K-ATPase

1990 • 169 citations

Ionic Mechanisms of Cell Volume Regulation in Leukocytes

1990 • 154 citations

Regulation of human neutrophil chemotaxis by intracellular pH.

1986 • 145 citations

Immunolocalization of anion exchanger AE2 and cation exchanger NHE-1 in distinct adjacent cells of gastric mucosa

1994 • 138 citations

Proton secretion by stimulated neutrophils. Significance of hexose monophosphate shunt activity as source of electrons and protons for the respiratory burst.

1984 • 135 citations

Activation of Proton Pumping in Human Neutrophils Occurs by Exocytosis of Vesicles Bearing Vacuolar-type H+-ATPases

1996 • 131 citations

Intracellular pH regulation during spreading of human neutrophils.

1996 • 128 citations

Cytoplasmic pH regulation in phorbol ester-activated human neutrophils

1986 • 126 citations

Migration-associated volume changes in neutrophils facilitate the migratory process in vitro

1994 • 123 citations

Volume changes in single N1E-115 neuroblastoma cells measured with a fluorescent probe

1995 • 122 citations

Amiloride-sensitive Na+/H+ exchange in human neutrophils: Mechanism of activation by chemotactic factors

1984 • 111 citations

Activation of vacuolar-type proton pumps by protein kinase C. Role in neutrophil pH regulation

1992 • 110 citations

Stimulation of monocyte chemotaxis by human growth hormone and its deactivation by somatostatin

1993 • 108 citations

ATP dependence of NHE-1, the ubiquitous isoform of the Na+/H+ antiporter. Analysis of phosphorylation and subcellular localization.

1994 • 107 citations

Function and structure of H-K-ATPase in the kidney

1995 • 104 citations

Chemotactic factor-induced activation of Na+/H+ exchange in human neutrophils. II. Intracellular pH changes.

1985 • 101 citations

Protein kinase C activates an H+ (equivalent) conductance in the plasma membrane of human neutrophils.

1991 • 92 citations

How do cells move along surfaces?

1993 • 87 citations

[3] Micropore filter methods for leukocyte chemotaxis

1988 • 86 citations

Oscillating activity of a Ca(2+)-sensitive K+ channel. A prerequisite for migration of transformed Madin-Darby canine kidney focus cells.

1994 • 84 citations

Intracellular calcium levels correlate with speed and persistent forward motion in migrating neutrophils

1995 • 79 citations

Volume changes in activated human neutrophils: The role of Na⁺/H⁺ exchange

1986 • 67 citations

Na+/H+ exchange activity during phagocytosis in human neutrophils: role of Fcgamma receptors and tyrosine kinases.

1996 • 66 citations

Antiarrhythmic effects of HOE642, a novel Na+-H+ exchange inhibitor, on ventricular arrhythmias in animal hearts

1996 • 63 citations

A conserved epitope on H+,K+-adenosine triphosphatase of parietal cells discerned by a murine gastritogenic T-cell clone

1994 • 61 citations

Chemotactic factor-induced activation of Na+/H+ exchange in human neutrophils. I. Sodium fluxes.

1985 • 56 citations

H(+)-ATPases of renal cortical and medullary endosomes are differentially sensitive to Sch-28080 and omeprazole

1994 • 56 citations

Abnormal activation of H+ conductance in NADPH oxidase-defective neutrophils.

1993 • 49 citations

Cytoplasmic pH determines K+ conductance in fused renal epithelial cells.

1988 • 44 citations

Molecular genetics of cell migration: Dictyostelium as a model system

1991 • 41 citations

Suppression of neointimal thickening and smooth muscle cell proliferation after arterial injury in the rat by inhibitors of Na(+)-H+ exchange.

1993 • 38 citations

Differential effects of two fluorescent probes on macrophage migration as assessed by manual and automated methods

1995 • 38 citations

Neutrophils increase volume during migration in vivo and in vitro.

1994 • 37 citations

Modification of Cellular Ion Transport by the Ha-ras Oncogene: Steps towards Malignant Transformation

1996 • 31 citations

Renal expression of the gene encoding the gastric H(+)-K(+)-ATPase beta-subunit

1995 • 26 citations

Plasticity of renal epithelial cells: the way a potassium channel supports migration.

1996 • 25 citations

Cell shrinkage stimulates bradykinin-induced cell membrane potential oscillations in NIH 3T3 fibroblasts expressing the ras-oncogene

1993 • 24 citations

Effects of bradykinin on cell volume and intracellular pH in NIH 3T3 fibroblasts expressing the ras oncogene

1992 • 21 citations

Chapter 10 Regulation and Functional Significance of Cytoplasmic pH in Phagocytic Leukocytes

1990 • 17 citations

Dissociation of human neutrophil activation events by prolonged treatment with amiloride.

1987 • 13 citations

Effects of HOE 694 — a novel inhibitor of Na+/H+ exchange — on NIH 3T3 fibroblasts expressing the RAS oncogene

1993 • 11 citations