The gene encoding the glutamate receptor subunit GluR5 is located on human chromosome 21q21.1-22.1 in the vicinity of the gene for familial amyotrophic lateral sclerosis.

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Principles of Neurology

1977 • 1,759 citations

High-Resolution Mapping of Human Chromosome 11 by in Situ Hybridization with Cosmid Clones

1990 • 1,357 citations

Decreased Glutamate Transport by the Brain and Spinal Cord in Amyotrophic Lateral Sclerosis

1992 • 1,170 citations

The Toxic Effect of Sodium L-Glutamate on the Inner Layers of the Retina

1957 • 1,061 citations

Cloning by functional expression of a member of the glutamate receptor family

1989 • 1,009 citations

Molecular Cloning and Functional Expression of Glutamate Receptor Subunit Genes

1990 • 925 citations

Guam Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Linked to a Plant Excitant Neurotoxin

1987 • 881 citations

Identification of a Site in Glutamate Receptor Subunits That Controls Calcium Permeability

1991 • 774 citations

Cloning of a novel glutamate receptor subunit, GluR5: Expression in the nervous system during development

1990 • 646 citations

Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA

1991 • 638 citations

Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis

1990 • 630 citations

The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits

1992 • 537 citations

Cloning of a putative high-affinity kainate receptor expressed predominantly in hippocampal CA3 cells

1991 • 461 citations

Familial adult motor neuron disease: amyotrophic lateralsclerosis

1986 • 401 citations

Cloning of a putative glutamate receptor: A low affinity kainate-binding subunit

1992 • 379 citations

Linkage of a Gene Causing Familial Amyotrophic Lateral Sclerosis to Chromosome 21 and Evidence of Genetic-Locus Heterogeneity

1991 • 373 citations

LATHYRISM: EVIDENCE FOR ROLE OF THE NEUROEXCITATORY AMINOACID BOAA

1986 • 373 citations

Excitatory amino acids and synaptic transmission: the evidence for a physiological function

1990 • 370 citations

A glutamate receptor channel with high affinity for domoate and kainate.

1992 • 336 citations

Delayed neurotoxicity of excitatory amino acids In vitro

1987 • 332 citations

Inciting Excitotoxic Cytocide Among Central Neurons

1986 • 231 citations

Cosmid vectors for rapid genomic walking, restriction mapping, and gene transfer.

1987 • 222 citations

The neuroexcitotoxic amino acids glutamate and aspartate are altered in the spinal cord and brain in amyotrophic lateral sclerosis

1988 • 210 citations

Neurotoxicity ofβ-N-methylamino-l-alanine (BMAA) andβ-N-oxalylamino-l-alamine (BOAA) on cultured cortical neurons

1989 • 206 citations

Neurotoxicity of excitatory amino acid receptor agonists in rat cerebellar slices: Dependence on calcium concentration

1986 • 204 citations

Primary structure and expression of the γ2 subunit of the glutamate receptor channel selective for kainate

1992 • 173 citations

Cysteine-S-Sulfate: Brain Damaging Metabolite in Sulfite Oxidase Deficiency1

1975 • 137 citations

High‐affinity kainate a domoate receptors in rat brain

1992 • 135 citations

Chromosomal localization of human glutamate receptor genes

1992 • 46 citations

Localization of the D5 dopamine receptor gene to human chromosome 4p15.1–p15.3, centromeric to the Huntington's disease locus

1992 • 30 citations