On the fidelity of DNA replication. Nucleoside monophosphate generation during polymerization.

Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid

1953 • 12,496 citations

Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High Specificity

1974 • 1,532 citations

Kinetic amplification of enzyme discrimination

1975 • 742 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1972 • 594 citations

Errors in DNA replication as a basis of malignant changes.

1974 • 527 citations

Active Center of DNA Polymerase

1969 • 416 citations

Studies on the Biochemical Basis of Spontaneous Mutation

1972 • 340 citations

Mutagenic DNA polymerase

1965 • 227 citations

A Study of Manganous Complexes by Paramagnetic Resonance Absorption

1954 • 225 citations

Induced mutagenesis in dam − mutants of Escherichia coli: A role for 6-methyladenine residues in mutation avoidance

1978 • 198 citations

The Deamination of Cytidine and Cytosine by Acidic Buffer Solutions. Mutagenic Implications^*

1966 • 191 citations

An in vitro transversion by a mutationally altered T4-induced DNA polymerase

1968 • 190 citations

A GENERAL SYNTHESIS OF NUCLEOSIDES-5′ TRIPHOSPHATES

1964 • 190 citations

The Infidelity of Avian Myeloblastosis Virus Deoxyribonucleic Acid Polymerase in Polynucleotide Replication

1974 • 172 citations

Error induction and correction by mutant and wild type T4 DNA polymerases. Kinetic error discrimination mechanisms.

1979 • 167 citations

Mismatch repair in heteroduplex DNA.

1975 • 165 citations

THE ACCOMMODATION OF NONCOMPLEMENTARY BASES IN HELICAL POLYRIBONUCLEOTIDES AND DEOXYRIBONUCLEIC ACIDS

1960 • 158 citations

Mechanism of Enzyme Action

1974 • 157 citations

THE FREQUENCY OF ERRORS IN PROTEIN BIOSYNTHESIS

1963 • 156 citations

A Comparison of Associated Enzyme Activities in Various Deoxyribonucleic Acid Polymerases

1973 • 126 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1969 • 117 citations

Antimutagenic DNA Polymerases of Bacteriophage T4

1968 • 114 citations

ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID, X. INFLUENCE OF BROMOURACIL SUBSTITUTIONS ON REPLICATION

1962 • 110 citations

Hydrolysis of Template and Newly Synthesized Deoxyribonucleic Acid by the 3′ to 5′ Exonuclease Activity of the T4 Deoxyribonucleic Acid Polymerase

1972 • 105 citations

Replicational Fidelity: Mechanisms of Mutation Avoidance and Mutation Fixation

1979 • 96 citations

Induction of mutations in bacteriophage T4 with divalent manganese

1965 • 95 citations

Selective inhibition of the 3' to 5' exonuclease activity associated with DNA polymerases: a mechanism of mutagenesis

1977 • 93 citations

On the fidelity of DNA replication. Lack of exodeoxyribonuclease activity and error-correcting function in avian myeloblastosis virus DNA polymerase.

1976 • 93 citations

On the Role of Deoxyribonucleic Acid Polymerase in Determining Mutation Rates

1973 • 85 citations

Control of mutation frequency by bacteriophage T4 DNA polymerase. I. The CB120 antimutator DNA polymerase is defective in strand displacement.

1976 • 84 citations

Control of mutation frequency by bacteriophage T4 DNA polymerase. II. Accuracy of nucleotide selection by the L88 mutator, CB120 antimutator, and wild type phage T4 DNA polymerases.

1976 • 82 citations

Conformation of deoxynucleoside triphosphate substrates on DNA polymerase I from Escherichia coli as determined by nuclear magnetic relaxation

1975 • 82 citations

On the fidelity of transcription by Escherichia coli ribonucleic acid polymerase

1975 • 78 citations

Association by Hydrogen Bonding of Mononucleotides in Aqueous Solution

1972 • 72 citations

Kinetic analysis of Escherichia coli deoxyribonucleic acid polymerase I.

1975 • 66 citations

On the fidelity of DNA replication. Metal activation of Escherichia coli DNA polymerase I.

1979 • 65 citations

On the fidelity of DNA replication. The accuracy of Escherichia coli DNA polymerase I in copying natural DNA in vitro.

1980 • 65 citations

ON THE SPECIFICITY OF DNA POLYMERASE

1967 • 58 citations

On the fidelity of DNA replication. Accuracy of Escherichia coli DNA polymerase I.

1979 • 57 citations

Deoxynucleotide-polymerizing Enzymes of Calf Thymus Gland

1972 • 45 citations

Molecular orbital (CNDO[complete neglect of differential overlap]2 and MINDO [modified intermediate neglect of differential overlap] calculations on protonated deoxyribonucleic acid bases. Effects of base protonation on intermolecular interactions)

1973 • 38 citations

Avian myeloblastosis virus DNA polymerase. Kinetic studies on the incorporation of noncomplementary nucleotides.

1975 • 38 citations

Helical complexes of polyriboinosinic acid with copolymers of polyribocytidylic acid containing inosine, adenosine and uridine residues

1971 • 37 citations

A new approach to DNA polymerase kinetics

1979 • 33 citations

A mechanism for keeping mutations in check

1965 • 26 citations