Experimental radioimmunotherapy of small peritoneal metastases of colorectal origin

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1978 • 4,673 citations

Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using protein A-Sepharose

1978 • 2,726 citations

Determination of the immunoreactive function of radiolabeled monoclonal antibodies by linear extrapolation to binding at infinite antigen excess

1984 • 923 citations

Peritioneal carcinomatosis in nongynecologic malignancy. A prospective study of prognostic factors

1989 • 597 citations

Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors.

1990 • 567 citations

MIRDOSE: Personal Computer Software for Internal Dose Assessment in Nuclear Medicine

1996 • 500 citations

Human colonic adenocarcinoma cells

1976 • 375 citations

Observations concerning cancer spread within the peritoneal cavity and concepts supporting an ordered pathophysiology

1996 • 176 citations

Complementation of intracavitary and intravenous administration of a monoclonal antibody (B72.3) in patients with carcinoma.

1987 • 166 citations

Peritoneal Carcinomatosis from Adenocarcinoma of the Colon

1996 • 159 citations

Radioimmunotherapy of small-volume disease of metastatic colorectal cancer

2002 • 113 citations

Long term survival of patients with advanced ovarian cancer treated with intraperitoneal radioimmunotherapy

2000 • 102 citations

The role of radiolabeled antibodies in the treatment of non-Hodgkin's lymphoma: the coming of age of radioimmunotherapy

2001 • 95 citations

Radioimmunoscintigraphy of colon cancer with iodine-131-labeled B72.3 monoclonal antibody.

1988 • 91 citations

Differential Reactivities of Carcinoembryonic Antigen (CEA) and CEA-Related Monoclonal and Polyclonal Antibodies in Common Epithelial Malignancies

1990 • 89 citations

Characterization of second-generation monoclonal antibodies against carcinoembryonic antigen

1993 • 84 citations

Prognostic value of microscopic peritoneal dissemination

2000 • 83 citations

Docetaxel: pharmacokinetics and tissue levels after intraperitoneal and intravenous administration in a rat model

2002 • 67 citations

Radiotherapy alone in the curative treatment of rectal carcinoma

2003 • 67 citations

Comparison of equitoxic radioimmunotherapy and chemotherapy in the treatment of human colonic cancer xenografts.

1994 • 58 citations

Radioimmunotherapy of nude mice with intraperitoneally growing ovarian cancer xenograft utilizing 211At-labelled monoclonal antibody MOv18.

2000 • 55 citations

Radioimmunotherapy of small volume disease of colorectal cancer metastatic to the liver: preclinical evaluation in comparison to standard chemotherapy and initial results of a phase I clinical study.

1999 • 55 citations

Cure of metastatic human colonic cancer in mice with radiolabeled monoclonal antibody fragments.

2000 • 55 citations

Variables influencing tumor dosimetry in radioimmunotherapy of CEA-expressing cancers with anti-CEA and antimucin monoclonal antibodies.

1997 • 53 citations

Antibody-guided localization of intraperitoneal tumors following intraperitoneal or intravenous antibody administration.

1987 • 53 citations

Factors influencing the pharmacokinetics, dosimetry, and diagnostic accuracy of radioimmunodetection and radioimmunotherapy of carcinoembryonic antigen-expressing tumors.

1996 • 49 citations

Comparison of the therapeutic efficacy of 211At- and 131I-labelled monoclonal antibody MOv18 in nude mice with intraperitoneal growth of human ovarian cancer.

2001 • 47 citations

Innovations that influence the pharmacology of monoclonal antibody guided tumor targeting.

1990 • 45 citations

Metastatic pattern of CC531 colon carcinoma cells in the abdominal cavity: an experimental model of peritoneal carcinomatosis in rats

2001 • 42 citations

The Curative and Palliative Potential of the Monoclonal Antibody MOv18 Labelled with²¹¹At in Nude Mice with Intraperitoneally growing Ovarian Cancer Xenografts - A Long-Term Study

2000 • 40 citations

Peritoneal carcinomatosis: imaging with intraperitoneal injection of I-131-labeled B72.3 monoclonal antibody.

1988 • 39 citations

Localization of the monoclonal antibody HMFG2 after intravenous and intraperitoneal injection into nude mice bearing subcutaneous and intraperitoneal human ovarian cancer xenografts.

1987 • 38 citations

Colorectal carcinoma and the relationship of peritoneal cytology

1997 • 36 citations

Carcinoembryonic Antigen as a Target for Radioimmunotherapy of Human Medullary Thyroid Carcinoma: Antibody Processing, Targeting, and Experimental Therapy with ¹³¹I and ⁹⁰Y Labeled MAbs

1999 • 36 citations

Antibody-targeted therapy for low-grade lymphoma.

1999 • 34 citations

Intraperitoneal radioimmunotherapy in an ovarian carcinoma mouse model: Effect of the radionuclide

2003 • 32 citations

Tumor Retention of ¹⁸⁶Re-MAG3, ¹¹¹In-DTPA and ¹²⁵I Labeled Monoclonal Antibody G250 in Nude Mice with Renal Cell Carcinoma Xenografts

1998 • 29 citations

Radioimmunotherapy of human colon carcinomatosis xenograft with 90Y-ZCE025 monoclonal antibody: toxicity and tumor phenotype studies.

1990 • 28 citations

Immunohistochemical analysis of tumor antigen saturation following injection of monoclonal antibody G250.

1999 • 27 citations

Targeting and initial radioimmunotherapy of medullary thyroid carcinoma with 131I-labeled monoclonal antibodies to carcinoembryonic antigen.

1995 • 27 citations

Comparison of radioimmunotherapy and external beam radiotherapy in colon cancer xenografts

1993 • 26 citations

Influence of antibody protein dose on therapeutic efficacy of radioiodinated antibodies in nude mice bearing GW-39 human tumor

1992 • 25 citations

Physiological factors influencing radioantibody uptake: A study of four human colonic carcinomas

1992 • 25 citations

Novel flow cytometric analysis of the progress and route of internalization of a monoclonal anti-carcinoembryonic antigen (CEA) antibody

1996 • 24 citations

Intratumoral and whole-body distributions of C110 anti-carcinoembryonic antigen radioimmunotoxin after intraperitoneal and intravenous injection: a quantitative autoradiographic study.

1992 • 19 citations

Radioimmunotherapy of peritoneal human colon cancer xenografts with site-specifically modified 212Bi-labeled antibody.

1990 • 18 citations

Effect of yttrium-90-labeled anti-carcinoembryonic antigen monoclonal antibody on the morphology and phenotype of human tumors grown as peritoneal carcinomatosis in athymic mice

1989 • 18 citations

Effect of the route of administration on the biodistribution of radioiodinated OV-TL 3 F(ab′)2 in experimental ovarian cancer

1994 • 12 citations