Regulatory role of metallothionein in NF‐κB activation

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

A rapid micrqpreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

1991 • 2,362 citations

Redox Regulation of NF-kappa B Activation

1997 • 852 citations

Oxygen free radicals and metallothionein

1993 • 848 citations

Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium.

1994 • 624 citations

Overexpression of Manganese Superoxide Dismutase Suppresses Tumor Necrosis Factor-induced Apoptosis and Activation of Nuclear Transcription Factor-κB and Activated Protein-1

1998 • 580 citations

Regulatory Role for a Novel Human Thioredoxin Peroxidase in NF-κB Activation

1997 • 414 citations

Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse.

1993 • 381 citations

Enhanced Sensitivity to Oxidative Stress in Cultured Embryonic Cells from Transgenic Mice Deficient in Metallothionein I and II Genes

1995 • 302 citations

Inhibition of I kappa B-alpha phosphorylation and degradation and subsequent NF-kappa B activation by glutathione peroxidase overexpression.

1996 • 283 citations

Thionein (apometallothionein) can modulate DNA binding and transcription activation by zinc finger containing factor Spl

1991 • 252 citations

Effects of oxidants and antioxidants on nuclear factor ϰB activation in three different cell lines: evidence against a universal hypothesis involving oxygen radicals

1995 • 206 citations

Zinc transfer from transcription factor IIIA fingers to thionein clusters.

1991 • 204 citations

Prevention of lethal and renal toxicity of cis-diamminedichloroplatinum(II) by induction of metallothionein synthesis without compromising its antitumor activity in mice.

1987 • 190 citations

Inhibition of the DNA‐binding activity of NF‐κB by gold compounds in vitro

1995 • 155 citations

Activation of nuclear factor kappaB: potential role in metallothionein-mediated mitogenic response.

1998 • 142 citations

Zinc and gene expression

1981 • 133 citations

Metallothioneins and Cell Death by Anticancer Drugs

1995 • 119 citations

Inhibition of AP‐1 and NF‐κB by manganese‐containing superoxide dismutase in human breast cancer cells

1998 • 110 citations

Sp1-Mediated Transcription of the Werner Helicase Gene Is Modulated by Rb and p53

1998 • 93 citations

Nucleophilic Distribution of Metallothionein in Human Tumor Cells

1996 • 41 citations

Simian virus 40-transformed metallothionein null cells showed increased sensitivity to cadmium but not to zinc, copper, mercury or nickel

1999 • 39 citations

Involvement of Oxidative Stress in Paraquat-Induced Metallothionein Synthesis Under Glutathione Depletion

1998 • 34 citations