A cytoskeleton-related gene, uso1, is required for intracellular protein transport in Saccharomyces cerevisiae.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.

1982 • 5,284 citations

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 • 4,231 citations

Intracellular Aspects of the Process of Protein Synthesis

1975 • 3,560 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

1979 • 2,930 citations

[1] Production of single-stranded plasmid DNA

1987 • 2,642 citations

Analysis of gene control signals by DNA fusion and cloning in Escherichia coli

1980 • 2,499 citations

Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway

1980 • 1,808 citations

Two differentially regulated mRNAs with different 5′ ends encode secreted and intracellular forms of yeast invertase

1982 • 1,539 citations

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

1988 • 1,504 citations

High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules.

1979 • 1,504 citations

Yeast transformation: a model system for the study of recombination.

1981 • 1,491 citations

MOLECULAR AND CELLULAR BIOLOGY OF INTERMEDIATE FILAMENTS

1988 • 1,395 citations

Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin a suggests an ER recycling pathway

1990 • 972 citations

Structure And Evolution Of Calcium-Modulated Protein

1980 • 942 citations

Relationship of actin and tubulin distribution to bud growth in wild-type and morphogenetic-mutant Saccharomyces cerevisiae.

1984 • 838 citations

Order of events in the yeast secretory pathway

1981 • 804 citations

The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery

1988 • 699 citations

Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro.

1989 • 588 citations

SNAPs, a family of NSF attachment proteins involved in intracellular membrane fusion in animals and yeast

1990 • 578 citations

The yeast secretory pathway is perturbed by mutations in PMR1, a member of a Ca2+ ATPase family

1989 • 535 citations

Phenotypic analysis of temperature-sensitive yeast actin mutants

1985 • 512 citations

Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration

1989 • 460 citations

A novel GTP-binding protein, Sar1p, is involved in transport from the endoplasmic reticulum to the Golgi apparatus.

1989 • 443 citations

A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum.

1987 • 418 citations

Isolation of the yeast calmodulin gene: Calmodulin is an essential protein

1986 • 400 citations

A yeast gene encoding a protein homologous to the human c-has/bas proto-oncogene product

1983 • 396 citations

Isolation of yeast mutants defective in protein targeting to the vacuole.

1986 • 394 citations

A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses

1989 • 392 citations

Many Random Sequences Functionally Replace the Secretion Signal Sequence of Yeast Invertase

1987 • 375 citations

ADP-ribosylation factor is functionally and physically associated with the Golgi complex.

1990 • 372 citations

Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast.

1989 • 339 citations

Periodic features in the amino acid sequence of nematode myosin rod

1983 • 301 citations

The ras-related YPT1 gene product in yeast: A GTP-binding protein that might be involved in microtubule organization

1986 • 281 citations

A membrane glycoprotein, Sec12p, required for protein transport from the endoplasmic reticulum to the Golgi apparatus in yeast.

1988 • 275 citations

Study of a temperature-sensitive mutant of the ras-related YPT1 gene product in yeast suggests a role in the regulation of intracellular calcium

1988 • 243 citations

Microtubules, membrane traffic, and cell organization

1990 • 229 citations

Characterization of a component of the yeast secretion machinery: identification of the SEC18 gene product.

1988 • 220 citations

Cell Interactions and Regulation of Cell Type in the Yeast Saccharomyces Cerevisiae

1983 • 189 citations

RECOMBINATION AND CHROMOSOME SEGREGATION DURING THE SINGLE DIVISION MEIOSIS IN SPO12–1 AND SPO13–1 DIPLOIDS

1980 • 170 citations

Anionic regions in nuclear proteins.

1987 • 167 citations

SEC7 encodes an unusual, high molecular weight protein required for membrane traffic from the yeast Golgi apparatus.

1988 • 145 citations

Dynamics of cytoplasmic organelles in the cell cycle of the fission yeast Schizosaccharomyces pombe: three-dimensional reconstruction from serial sections

1989 • 134 citations

Yeast secretory mutants that block the formation of active cell surface enzymes.

1984 • 131 citations

Yeast Sec23p acts in the cytoplasm to promote protein transport from the endoplasmic reticulum to the Golgi complex in vivo and in vitro.

1989 • 128 citations

Characterization of new mutants in the early part of the yeast secretory pathway isolated by a [3H]mannose suicide selection.

1987 • 127 citations

Calcium-sensitive cls4 mutant of Saccharomyces cerevisiae with a defect in bud formation

1986 • 93 citations

Sec2 protein contains a coiled-coil domain essential for vesicular transport and a dispensable carboxy terminal domain.

1990 • 80 citations

Characterization of a Component of the Yeast Secretion Machinery: Identification of the SEC18 Gene Product

1988 • 79 citations

In vivo and in vitro analysis of ptl1, a yeast ts mutant with a membrane-associated defect in protein translocation.

1988 • 79 citations

GENE DUPLICATION IN SACCHAROMYCES CEREVISIAE

1978 • 74 citations

Synthesis of an O-glycosylated cell surface protein induced in yeast by α factor

1986 • 64 citations

Secretory granules and endosomes show saltatory movement biased to the anterograde and retrograde directions, respectively, along microtubules in AtT20 cells.

1989 • 47 citations

Pheromone induction of agglutination in Saccharomyces cerevisiae a cells

1987 • 16 citations