Riluzole specifically blocks inactivated Na channels in myelinated nerve fibre

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction.

1977 • 1,746 citations

Time- and voltage-dependent interactions of antiarrhythmic drugs with cardiac sodium channels

1977 • 899 citations

A new voltage clamp method for Ranvier nodes

1969 • 248 citations

Voltage clamp analysis of the inhibitory actions of diphenylhydantoin and carbamazepine on voltage-sensitive sodium channels in neuroblastoma cells.

1985 • 225 citations

Quantitative description of sodium currents in myelinated nerve fibres of Xenopus laevis

1960 • 223 citations

2-Amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission—II Biochemical properties

1985 • 201 citations

Inactivation of sodium channels: second order kinetics in myelinated nerve

1977 • 201 citations

2-Amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission—I

1985 • 193 citations

Electrophysiology of the Peripheral Myelinated Nerve

1976 • 113 citations

Evidence for two transient sodium currents in the frog node of Ranvier.

1985 • 109 citations

Evidence for two components of sodium channel block by lidocaine in isolated cardiac myocytes.

1988 • 82 citations

Behaviour of chemically modified sodium channels in frog nerve supports a three-state model of inactivation

1985 • 33 citations

Action of benzocaine on sodium channels of frog nodes of ranvier treated with chloramine-T

1987 • 32 citations

Effects of benzocaine on the kinetics of normal and batrachotoxin-modified Na channels in frog node of Ranvier

1986 • 20 citations

Voltage and temperature dependence of normal and chemically modified inactivation of sodium channels

1989 • 13 citations

Cooperativity of tetrodotoxin action in the frog node of Ranvier

1985 • 8 citations

Mechanism of action of a structural analog of alphaxalone on myelinated nerve fibre

1988 • 7 citations