Developmental Excitation of Corticothalamic Neurons by Nicotinic Acetylcholine Receptors

The Rat Brain in Stereotaxic Coordinates

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AChE-stained horizontal sections of the rat brain in stereotaxic coordinates

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Grouping of brain rhythms in corticothalamic systems

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A missense mutation in the neuronal nicotinic acetylcholine receptor α4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy

1995 • 1,112 citations

Physiological Diversity of Nicotinic Acetylcholine Receptors Expressed by Vertebrate Neurons

1995 • 1,017 citations

Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs

2006 • 838 citations

Synaptic Mechanisms Underlie Nicotine-Induced Excitability of Brain Reward Areas

2002 • 685 citations

Variants in Nicotinic Receptors and Risk for Nicotine Dependence

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The maternal and fetal physiologic effects of nicotine

1996 • 560 citations

Nicotine binding and nicotinic receptor subunit RNA after chronic nicotine treatment

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At what age is the developing cerebral cortex of the rat comparable to that of the full-term newborn human baby?

1991 • 535 citations

Cholinergic systems in brain development and disruption by neurotoxicants: nicotine, environmental tobacco smoke, organophosphates

2004 • 524 citations

α-5/α-3 nicotinic receptor subunit alleles increase risk for heavy smoking

2008 • 460 citations

Cholinergic Switching Within Neocortical Inhibitory Networks

1998 • 452 citations

Desensitization of neuronal nicotinic receptors

2002 • 447 citations

The nicotinic receptor β2 subunit is mutant in nocturnal frontal lobe epilepsy

2000 • 441 citations

Functional contributions of α5 subunit to neuronal acetylcholine receptor channels

1996 • 389 citations

Higher levels of nicotine in arterial than in venous blood after cigarette smoking

1993 • 374 citations

Cholinergic Activity in Autism: Abnormalities in the Cerebral Cortex and Basal Forebrain

2001 • 371 citations

Differential Desensitization and Distribution of Nicotinic Acetylcholine Receptor Subtypes in Midbrain Dopamine Areas

2003 • 363 citations

Cigarette Smoking Saturates Brain α4β2 Nicotinic Acetylcholine Receptors

2006 • 353 citations

Abnormal Regulation of High Affinity Nicotinic Receptors in Subjects with Schizophrenia

2000 • 340 citations

Are maternal smoking and stress during pregnancy related to ADHD symptoms in children?

2004 • 328 citations

α4β2 Nicotinic Receptors with High and Low Acetylcholine Sensitivity: Pharmacology, Stoichiometry, and Sensitivity to Long-Term Exposure to Nicotine

2006 • 268 citations

The distribution of mRNA encoded by a new member of the neuronal nicotinic acetylcholine receptor gene family (α5) in the rat central nervous system

1990 • 254 citations

Distributed Network Actions by Nicotine Increase the Threshold for Spike-Timing-Dependent Plasticity in Prefrontal Cortex

2007 • 243 citations

Maternal smoking during pregnancy as an environmental risk factor for attention deficit hyperactivity disorder behaviour. A review.

2005 • 225 citations

Postnatal growth and morphological development of the brain: a species comparison

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Nicotinic modulation of neuronal networks: from receptors to cognition

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Effects of prenatal nicotine exposure on development of central and peripheral cholinergic neurotransmitter systems. Evidence for cholinergic trophic influences in developing brain.

1989 • 200 citations

Comparative distribution of nicotinic receptor subtypes during development, adulthood and aging: an autoradiographic study in the rat brain

2004 • 200 citations

Nicotinic receptors in the rat prefrontal cortex: increase in glutamate release and facilitation of mediodorsal thalamo‐cortical transmission

1999 • 193 citations

Ca²⁺Permeability of the (α4)₃(β2)₂Stoichiometry Greatly Exceeds That of (α4)₂(β2)₃Human Acetylcholine Receptors

2006 • 193 citations

The Nicotinic Acetylcholine Receptor Subunit α5 Mediates Short-Term Effects of Nicotine in Vivo

2003 • 192 citations

Roles of Accessory Subunits in α4β2^*Nicotinic Receptors

2008 • 188 citations

The CHRNA5/A3/B4 Gene Cluster Variability as an Important Determinant of Early Alcohol and Tobacco Initiation in Young Adults

2008 • 185 citations

Nicotinic receptors in human brain: topography and pathology

2000 • 181 citations

Laminar distribution of nicotinic receptor subtypes in cortical regions in schizophrenia

2001 • 173 citations

Nicotinic control of axon excitability regulates thalamocortical transmission

2007 • 166 citations

Alteration of the in vivo nicotinic receptor density in ADNFLE patients: a PET study

2006 • 165 citations

Executive and social behaviors under nicotinic receptor regulation

2003 • 160 citations

Nicotine sensitization increases dendritic length and spine density in the nucleus accumbens and cingulate cortex

2001 • 152 citations

Molecular analysis of nicotinic receptor expression in autism

2004 • 136 citations

Perinatal exposure to nicotine causes deficits associated with a loss of nicotinic receptor function

2005 • 134 citations

Hypocretin and Nicotine Excite the Same Thalamocortical Synapses in Prefrontal Cortex: Correlation with Improved Attention in Rat

2005 • 128 citations

Smoking During Pregnancy and Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type: A Case-Control Study

2006 • 125 citations

Excitatory Connections Made by Presynaptic Cortico-Cortical Pyramidal Cells in Layer 6 of the Neocortex

2005 • 114 citations

Layer 6 Cortico-thalamic Pyramidal Cells Preferentially Innervate Interneurons and Generate Facilitating EPSPs

2005 • 104 citations

The role of the nicotinic acetylcholine receptors in sleep-related epilepsy

2007 • 98 citations

Neonatal nicotine exposure impairs nicotinic enhancement of central auditory processing and auditory learning in adult rats

2006 • 90 citations

Nicotinic α5 subunit deletion locally reduces high‐affinity agonist activation without altering nicotinic receptor numbers

2007 • 84 citations

Conditional Expression in Corticothalamic Efferents Reveals a Developmental Role for Nicotinic Acetylcholine Receptors in Modulation of Passive Avoidance Behavior

2003 • 80 citations

Expression of ?5 nicotinic acetylcholine receptor subunit mRNA during hippocampal and cortical development

2004 • 80 citations

Sleep Oscillations Developing into Seizures in Corticothalamic Systems

2003 • 73 citations

Attention-deficit/hyperactivity disorder: A plausible mouse model?

2006 • 46 citations

Autosomal dominant nocturnal frontal lobe epilepsy with a mutation in the CHRNB2 gene

2007 • 45 citations

The nicotinic acetylcholine receptor agonist (±)-epibatidine increases FGF-2 mRNA and protein levels in the rat brain

1999 • 36 citations