Back to search

Has Cox-2 a prognostic role in non-small-cell lung cancer? A systematic review of the literature with meta-analysis of the survival results

Data up to Jan 2025

Published2006
Citations59
References54

Total Citations Per Year

Abstract

References (54)

Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints

1998 • 4,679 citations

Beta blockade during and after myocardial infarction: An overview of the randomized trials

1985 • 3,248 citations

Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential

1997 • 1,411 citations

Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors.

2000 • 1,310 citations

Cancer incidence and mortality in Europe, 2004

2005 • 1,218 citations

Cancer incidence and mortality in Europe

1989 • 1,005 citations

Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas.

1998 • 825 citations

Expression of cyclooxygenase-2 in human lung carcinoma.

1998 • 729 citations

Why there are two cyclooxygenase isozymes

2001 • 612 citations

The role of RAS oncogene in survival of patients with lung cancer: a systematic review of the literature with meta-analysis

2004 • 602 citations

Sulindac for polyposis of the colon

1983 • 521 citations

Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: up-regulation of interleukin 10 and down-regulation of interleukin 12 production.

1998 • 498 citations

NS398, a selective cyclooxygenase-2 inhibitor, induces apoptosis and down-regulates bcl-2 expression in LNCaP cells.

1998 • 439 citations

Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer.

2001 • 410 citations

Role of p53 as a prognostic factor for survival in lung cancer: a systematic review of the literature with a meta-analysis

2001 • 409 citations

Prognostic factors for survival in advanced non-small-cell lung cancer: univariate and multivariate analyses including recursive partitioning and amalgamation algorithms in 1,052 patients. The European Lung Cancer Working Party.

1995 • 396 citations

Cyclooxygenase-2 inhibitor induces apoptosis and enhances cytotoxicity of various anticancer agents in non-small cell lung cancer cell lines.

2000 • 322 citations

Prognostic significance of elevated cyclooxygenase 2 expression in primary, resected lung adenocarcinomas.

1999 • 315 citations

The role of EGF-R expression on patient survival in lung cancer: a systematic review with meta-analysis

2002 • 267 citations

Ki-67 expression and patients survival in lung cancer: systematic review of the literature with meta-analysis

2004 • 265 citations

The role of microvessel density on the survival of patients with lung cancer: a systematic review of the literature with meta-analysis

2002 • 237 citations

Prognostic factors for patients with small cell lung carcinoma

2000 • 224 citations

Cyclooxygenase‐2: A novel molecular target for the prevention and treatment of head and neck cancer

2002 • 220 citations

Prognostic significance of cyclooxygenase-2 pathway and angiogenesis in head and neck squamous cell carcinoma

2002 • 214 citations

Increased cyclooxygenase 2 (COX-2) expression occurs frequently in precursor lesions of human adenocarcinoma of the lung

2000 • 208 citations

Nitric oxide synthase, cyclooxygenase 2, and vascular endothelial growth factor in the angiogenesis of non-small cell lung carcinoma.

2000 • 205 citations

Regulation of Cyclooxgenase-2 mRNA Stability by Taxanes

2003 • 195 citations

Role of cyclooxygenase-2 in colorectal cancer

2003 • 191 citations

Increased expression of cyclooxygenase-2 in human pancreatic neoplasms and potential for chemoprevention by cyclooxygenase inhibitors

2001 • 184 citations

Role of Bcl-2 as a prognostic factor for survival in lung cancer: a systematic review of the literature with meta-analysis

2003 • 163 citations

Prognostic Factors in Resected Stage I Non–Small-Cell Lung Cancer: A Multivariate Analysis of Six Molecular Markers

2004 • 145 citations

Prognostic Significance of Cyclooxygenase 2 mRNA Expression in Non-Small Cell Lung Cancer

2002 • 128 citations

The role of HER-2/neu expression on the survival of patients with lung cancer: a systematic review of the literature

2003 • 112 citations

Expression of cyclooxygenase‐1 and cyclooxygenase‐2 in bronchial epithelium and nonsmall cell lung carcinoma

2002 • 95 citations

HER2 and COX2 expression in human prostate cancer

2003 • 92 citations

Cyclooxygenase‐2 is expressed frequently and early in Barrett's oesophagus and associated adenocarcinoma

2003 • 87 citations

Correlation between cyclooxygenase-2 and tumor angiogenesis in non-small cell lung cancer

2003 • 79 citations

Elevated cyclooxygenase-2 expression correlates with distant metastases in breast cancer.

2004 • 78 citations

Cyclooxygenase‐2 (COX‐2) mRNA Expression Levels in Normal Lung Tissues and Non‐small Cell Lung Cancers

1999 • 77 citations

Total cyclooxygenase‐2 mRNA levels correlate with vascular endothelial growth factor mRNA levels, tumor angiogenesis and prognosis in non‐small cell lung cancer patients

2005 • 76 citations

COX-2, MMP-9, and Noguchi Classification Provide Additional Prognostic Information About Adenocarcinoma of the Lung: A Study of 117 Patients From Brazil

2004 • 74 citations

[VEGF and survival of patients with lung cancer: a systematic literature review and meta-analysis].

2002 • 65 citations

PROGNOSTIC MARKERS IN RESECTABLE NON–SMALL CELL LUNG CANCER

1997 • 64 citations

Chemotherapy Induces the Expression of Cyclooxygenase-2 in Non–Small Cell Lung Cancer

2005 • 60 citations

VEGF et survie des patients atteints d'un cancer pulmonaire. Revue systématique avec méta-analyse.

2002 • 55 citations

Molecular and biological factors in the prognosis of non-small cell lung cancer

1995 • 45 citations

HER-2, EGFR, COX-2 Expression status correlated to microvessel density and survival in resected non-small cell lung cancer

2004 • 38 citations

Prognostic Significance of Cyclooxygenase 2 Expression in 259 Cases of Non-Small Cell Lung Cancer

2005 • 38 citations

COX-2 expression during early lung squamous cell carcinoma oncogenesis

2005 • 36 citations

Prognostic Significance of Cyclooxygenase 2 Expression in 259 Cases of Non–Small Cell Lung Cancer

2005 • 34 citations

Neuroendocrine and biologic features of primary tumors and tissue in pulmonary large cell carcinomas

2004 • 26 citations

Cyclooxygenase-2 protein levels are independent of epidermal growth factor receptor expression or activation in operable non-small cell lung cancer

2004 • 24 citations

COX-2, MMP-9, and Noguchi Classification Provide Additional Prognostic Information About Adenocarcinoma of the Lung

2004 • 22 citations

Co-expression of Cox-2 and EGFR in stage I human bronchial adenocarcinomas

2004 • 14 citations

Cited By (0)

No citing papers found in database

Has Cox-2 a prognostic role in non-small-cell lung cancer? A systematic review of the… (2006) – British Journal of Cancer | Metascience Observatory Explorer