PROGNOSTIC MARKERS IN RESECTABLE NON–SMALL CELL LUNG CANCER

Cancer statistics, 1996

1996 • 1,807 citations

A New International Staging System for Lung Cancer

1986 • 1,652 citations

Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor

1986 • 1,226 citations

Incidence of local recurrence and second primary tumors in resected stage I lung cancer

1995 • 971 citations

K-rasOncogene Activation as a Prognostic Marker in Adenocarcinoma of the Lung

1990 • 811 citations

Relation of neovascularisation to metastasis of non-small-cell lung cancer

1992 • 780 citations

Prognosis and survival in resected lung carcinoma based on the new international staging system

1988 • 708 citations

High levels of p53 protein in UV-irradiated normal human skin.

1993 • 689 citations

bcl-2 Protein in Non-Small-Cell Lung Carcinoma

1993 • 684 citations

Keynote address on biostatistics and data retrieval.

1973 • 476 citations

p185neu expression in human lung adenocarcinomas predicts shortened survival.

1990 • 440 citations

Postsurgical Stage I Bronchogenic Carcinoma: Morbid Implications of Recurrent Disease

1984 • 386 citations

Accumulation of p53 protein correlates with a poor prognosis in human lung cancer.

1992 • 384 citations

Clinical significance of ras oncogene activation in human lung cancer

1993 • 361 citations

The Effect of Surgical Treatment on Survival from Early Lung Cancer

1992 • 353 citations

p185, a product of the neu proto-oncogene, is a receptorlike protein associated with tyrosine kinase activity.

1986 • 341 citations

Prognostic significance of p53 mutations and 3p deletions in primary, resected non-small cell lung cancer

1995 • 333 citations

Stage I nonsmall cell lung cancer. A multivariate analysis of treatment methods and patterns of recurrence

1995 • 323 citations

Frequency and prognostic significance of isolated tumour cells in bone marrow of patients with non-small-cell lung cancer without overt metastases

1996 • 314 citations

Commentary from Westminster

1984 • 309 citations

A prognostic model of recurrence and death in stage I non-small cell lung cancer utilizing presentation, histopathology, and oncoprotein expression.

1995 • 300 citations

Lung cancer detection results of a randomized prospective study in Czechoslovakia

1986 • 290 citations

Prognostic factors in patients with resected stage I non-small cell lung cancer. A report from the Lung Cancer Study Group

1984 • 279 citations

Expression of mutant p53 proteins in lung cancer correlates with the class of p53 gene mutation

1993 • 275 citations

ras gene mutations in non-small cell lung cancers are associated with shortened survival irrespective of treatment intent.

1991 • 249 citations

Correlation of Expression of H/Le^Y/Le^BAntigens with Survival in Patients with Carcinoma of the Lung

1992 • 235 citations

Screening for Lung Cancer

1989 • 231 citations

Expression of Blood-Group Antigen A — A Favorable Prognostic Factor in Non-Small-Cell Lung Cancer

1991 • 221 citations

Mutations of the p53 Gene as a Predictor of Poor Prognosis in Patients With Non-Small-Cell Lung Cancer

1993 • 213 citations

Bcl-2 protein: a prognostic factor inversely correlated to p53 in non-small-cell lung cancer

1995 • 201 citations

Prognostic value of c-erbB-2 protein expression in human lung adenocarcinoma and squamous cell carcinoma

1991 • 185 citations

Immunohistochemical assessment of individual tumor cells in lymph nodes of patients with non-small-cell lung cancer.

1994 • 183 citations

C-erbB-2 expression and codon 12 K-ras mutations both predict shortened survival for patients with pulmonary adenocarcinomas.

1994 • 182 citations

PLOIDY AS A PROGNOSTIC DETERMINANT IN SURGICALLY TREATED LUNG CANCER

1987 • 174 citations

Frequency and Distribution of Occult Micrometastases in Lymph Nodes of Patients With Non-Small-Cell Lung Carcinoma

1993 • 173 citations

Survival after resection of stage II non-small cell lung cancer

1992 • 170 citations

Screening for Lung Cancer

1997 • 168 citations

Histopathologic prognostic factors in adenocarcinomas of the peripheral lung less than 2 CM in diameter

1988 • 161 citations

Expression of p53 oncoprotein in non-small-cell lung cancer: a favorable prognostic factor.

1995 • 160 citations

Prognostic impact of mutated K-ras gene in surgically resected non-small cell lung cancer patients

1994 • 156 citations

The relationship of p53 immunostaining to survival in carcinoma of the lung

1992 • 147 citations

Molecular and pathologic markers in stage I non-small-cell carcinoma of the lung.

1995 • 141 citations

Five-year follow-up study of independent clinical and flow cytometric prognostic factors for the survival of patients with non-small cell lung carcinoma.

1988 • 141 citations

Site of Recurrence in Patients with Stages I and II Carcinoma of the Lung Resected for Cure

1981 • 141 citations

p53 Alterations in non-small cell lung cancers correlate with metastatic involvement of hilar and mediastinal lymph nodes

1994 • 133 citations

Prognostic significance of abnormal p53 accumulation in primary, resected non-small-cell lung cancers.

1996 • 133 citations

Prognostic implications of the International Staging System for Lung Cancer.

1988 • 132 citations

Altered Retinoblastoma Protein Expression and Prognosis in Early-Stage Non-Small-Cell Lung Carcinoma

1994 • 130 citations

Overexpression of the c‐erbB‐2/neu–encoded p185 protein in primary lung cancer

1992 • 129 citations

Blood vessel invasion by tumor cells predicts recurrence in completely resected T1 N0 M0 non-small-cell lung cancer

1993 • 119 citations

Prognostic factors in surgically resected limited-stage, nonsmall cell carcinoma of the lung

1984 • 116 citations

Postresection Irradiation for T2 N0 M0 Non–Small Cell Carcinoma: A Prospective, Randomized Study

1996 • 103 citations

Surgical results and prognostic factors of pathologic N1 disease in non-small-cell carcinoma of the lung

1994 • 100 citations

Prognostic significance of the expression ofras oncogene product in non-small cell lung cancer

1992 • 98 citations

Nonanatomic prognostic factors in carcinoma of the lung. A multivariate analysis

1982 • 96 citations

Postoperative T1 N0 non-small cell lung cancer

1987 • 93 citations

Prognostic and therapeutic significance of the flow cytometric nuclear DNA content in non-small cell lung cancer

1990 • 91 citations

National survey of the pattern of care for carcinoma of the lung

1990 • 82 citations

Is T factor of the TNM staging system a predominant prognostic factor in pathologic stage I non-small-cell lung cancer ? A multivariate prognostic factor analysis of 151 patients.

1993 • 82 citations

Prognostic significance of p53 andras p21 expression in nonsmall cell lung cancer

1995 • 81 citations

Prognostic Significance of the Proliferation Index in Surgically Resected Non—Small-Cell Lung Cancer

1993 • 79 citations

The effect of tumor size and tumor cell DNA content on the survival of patients with stage I adenocarcinoma of the lung

1989 • 79 citations

Symptomatic Patterns, Biologic Behavior, and Prognosis in Cancer of the Lung

1964 • 77 citations

Immunohistochemical study of cathepsin B. Prognostic significance in human lung cancer

1994 • 76 citations

Correlation of expression of ABH blood group carbohydrate antigens with metastatic potential in human lung carcinomas

1993 • 74 citations

Preoperative carcinoembryonic antigen level as a prognostic indicator in resected primary lung cancer

1994 • 73 citations

Is T factor of the TNM staging system a predominant prognostic factor in pathologic stage I non-small-cell lung cancer?

1993 • 67 citations

Flow cytometric analysis of the DNA content of non-small cell lung cancer ploidy as a significant prognostic indicator in squamous cell carcinoma of the lung

1990 • 66 citations

Proliferating cell nuclear antigen expression and argyrophilic nucleolar organizer regions as factors influencing prognosis of surgically treated lung cancer patients.

1993 • 65 citations

Limitation of annual screening chest radiography for the diagnosis of lung cancer. A retrospective study

1993 • 62 citations

Prognostic factors in resected stages I and II adenocarcinoma of the lung

1990 • 58 citations

Current status of screening for lung cancer.

1994 • 55 citations

The percentage of aneuploid cells is significantly correlated with survival in accurately staged patients with stage 1 resected squamous cell lung cancer and long-term follow up

1989 • 54 citations

Molecular Foundations of Oncology

1992 • 52 citations

A flow cytometric study of non-small cell lung cancer classified as T1N0

1992 • 47 citations

Expression of Lewis-related antigen and prognosis in stage I non—small cell lung cancer

1995 • 39 citations

Prognostic significance of parenchymal lymphatic vessel and blood vessel invasion in carcinoma of the lung.

1983 • 34 citations

Prognostic significance of basement membrane deposition in operable squamous cell carcinomas of the lung

1991 • 30 citations

DNA content in correlation with postsurgical stage in non-small cell lung cancer

1992 • 28 citations

Immunostains for blood group antigens lack prognostic significance in T1 lung carcinoma

1995 • 28 citations

Prognostic implications of histopathologic subtyping in patients with surgically treated stage I or II adenocarcinoma of the lung

1989 • 27 citations

Prognostic significance of serum ca 125 antigen assay in patients with non-small cell lung cancer

1994 • 26 citations

Use of Tumor Markers in Lung Cancer

1994 • 23 citations

Long-term survival of patients with lung cancer from a defined geographical area before and after radiological screening

1996 • 6 citations

The molecular biology of lung cancer

1991 • 4 citations

Results of resection for bronchogenic carcinoma in patients over the age of 80

1994 • 2 citations

The clinical significance of ras oncogene mutations in non-small cell lung cancer

1994 • 1 citations