Biological Aspects of the Link between Smoking and Depression

Principles of neural science

1982 • 9,410 citations

A Controlled Trial of Sustained-Release Bupropion, a Nicotine Patch, or Both for Smoking Cessation

1999 • 1,635 citations

Acetylcholine receptors containing the β2 subunit are involved in the reinforcing properties of nicotine

1998 • 1,304 citations

A Comparison of Sustained-Release Bupropion and Placebo for Smoking Cessation

1997 • 1,273 citations

Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs

1996 • 1,083 citations

The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine

1992 • 827 citations

Nicotinic Receptors in the Development and Modulation of CNS Synapses

1996 • 771 citations

Bupropion: a review of its mechanism of antidepressant activity.

1995 • 693 citations

Inhibition of monoamine oxidase B in the brains of smokers

1996 • 666 citations

Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain

1995 • 659 citations

Major Depression and Stages of Smoking

1998 • 644 citations

Molecular and Cellular Aspects of Nicotine Abuse

1996 • 605 citations

Evidence that Tobacco Smoking Increases the Density of (−)‐[³H]Nicotine Binding Sites in Human Brain

1988 • 554 citations

The effectiveness of the nicotine patch for smoking cessation. A meta-analysis

1994 • 533 citations

Nicotinic systems and cognitive function

1992 • 519 citations

Meta-analysis on efficacy of nicotine replacement therapies in smoking cessation

1994 • 489 citations

Nicotine-Induced Limbic Cortical Activation in the Human Brain: A Functional MRI Study

1998 • 483 citations

Effects of acute subcutaneous nicotine on attention, information processing and short-term memory in alzheimer's disease

1992 • 478 citations

Nicotine Dependence and Major Depression

1993 • 459 citations

Brain monoamine oxidase A inhibition in cigarette smokers

1996 • 427 citations

NMDA application potentiates synaptic transmission in the hippocampus

1988 • 421 citations

Glutamate-induced long-term potentiation of the frequency of miniature synaptic currents in cultured hippocampal neurons

1992 • 421 citations

Psychiatric comorbidity of smoking and nicotine dependence

1995 • 401 citations

Nortriptyline and Cognitive-Behavioral Therapy in the Treatment of Cigarette Smoking

1998 • 400 citations

Alteration in nicotine binding sites in Parkinson's disease, Lewy body dementia and Alzheimer's disease: Possible index of early neuropathology

1995 • 385 citations

The paradox of nicotinic acetylcholine receptor upregulation by nicotine

1990 • 350 citations

Effects of scopolamine and nicotine on human rapid information processing performance

1984 • 350 citations

Depression and depressive symptoms in smoking cessation

1990 • 347 citations

Drug Addiction: The Yin and Yang of Hedonic Homeostasis

1996 • 345 citations

Choline and Selective Antagonists Identify Two Subtypes of Nicotinic Acetylcholine Receptors that Modulate GABA Release from CA1 Interneurons in Rat Hippocampal Slices

1999 • 334 citations

Transdermal nicotine effects on attention

1998 • 334 citations

Synaptic Potentials Mediated via α-Bungarotoxin-Sensitive Nicotinic Acetylcholine Receptors in Rat Hippocampal Interneurons

1998 • 334 citations

Neuronal nicotinic acetylcholine receptor activation modulates gamma-aminobutyric acid release from CA1 neurons of rat hippocampal slices.

1997 • 330 citations

Cigarette Smoking and Major Depression

1998 • 306 citations

GABAA receptor antagonism in the extended amygdala decreases ethanol self-administration in rats

1995 • 302 citations

Effect of nicotine on the tobacco withdrawal syndrome

1984 • 293 citations

Efficacy of bupropion for smoking cessation in smokers with a former history of major depression or alcoholism∗

1999 • 278 citations

Nicotinic Stimulation Produces Multiple Forms of Increased Glutamatergic Synaptic Transmission

1998 • 274 citations

Major depression following smoking cessation

1997 • 263 citations

Under Siege: The Brain on Opiates

1996 • 263 citations

Cognitive-behavioral intervention increases abstinence rates for depressive-history smokers.

1994 • 257 citations

Nicotinic and muscarinic modulations of excitatory synaptic transmission in the rat prefrontal cortexin vitro

1993 • 244 citations

Comparison of the regional expression of nicotinic acetylcholine receptor ?7 mRNA and [125I]-?-bungarotoxin binding in human postmortem brain

1997 • 233 citations

Effects of Smoking on Rapid Information Processing Performance

1983 • 232 citations

Cognitive performance effects of subcutaneous nicotine in smokers and never-smokers

1996 • 231 citations

Predictors of outcome and recidivism in smoking cessation treatment

1978 • 221 citations

Psychosocial, behavioural, and health determinants of successful smoking cessation: a longitudinal study of Danish adults

1998 • 211 citations

Antidepressant effects of nicotine in an animal model of depression

1999 • 208 citations

Depression and smoking cessation: Characteristics of depressed smokers and effects of nicotine replacement.

1996 • 202 citations

A Randomized Trial of Nortriptyline for Smoking Cessation

1998 • 199 citations

Chapter 10 Structure and function of neuronal nicotinic acetylcholine receptors

1996 • 180 citations

Smoking cessation, clonidine, and vulnerability to nicotine among dependent smokers

1993 • 175 citations

Presynaptic Nicotinic Receptors Facilitate Monoaminergic Transmission

1998 • 174 citations

A reversible monoamine oxidase A inhibitor (moclobemide) facilitates smoking cessation and abstinence in heavy, dependent smokers*

1995 • 167 citations

Pharmacology of memory: cholinergic—glutamatergic interactions

1995 • 163 citations

Effects of local and repeated systemic administration of (−)nicotine on extracellular levels of acetylcholine, norepinephrine, dopamine, and serotonin in rat cortex

1995 • 154 citations

Nicotine enhances delayed matching-to-sample performance by primates

1988 • 144 citations

The separate and combined effects of scopolamine and nicotine on human information processing

1984 • 142 citations

Antidepressantlike Effects of Chronic Nicotine on Learned Helplessness Paradigm in Rats

1998 • 139 citations

A low dose of subcutaneous nicotine improves information processing in non-smokers

1994 • 131 citations

Low platelet monoamine oxidase activity in cigarette smokers

1981 • 130 citations

Alcohol Addiction: An Enigma among Us

1996 • 130 citations

Enhancement of sustained attention performance by the nicotinic acetylcholine receptor agonist ABT-418 in intact but not basal forebrain-lesioned rats

1999 • 129 citations

Irreversible inhibition of monoamine oxidase by some components of cigarette smoke

1987 • 120 citations

Cigarette smoking and cognitive performance

1992 • 118 citations

Mood and depression diagnosis in smoking cessation.

1995 • 112 citations

The effects of cigarettes of varying yield on rapid information processing performance

1984 • 112 citations

Doxepin as an adjunct to smoking cessation: a double-blind pilot study

1989 • 111 citations

Development of Major Depressive Disorder During Smoking-Cessation Treatment

1996 • 107 citations

The Nicotine Inhaler in Smoking Cessation

1997 • 107 citations

Release of dopamine and 5-hydroxytryptamine from rat striatal slices following activation of nicotinic cholinergic receptors

1983 • 102 citations

Blockade of hippocampal nicotinic receptors impairs working memory but not reference memory in rats

1993 • 100 citations

Chronic Nicotine Administration Differentially Affects Neurotransmitter Release from Rat Striatal Slices

1994 • 91 citations

Distribution of Nicotinic Subtypes in Human Brain

1995 • 90 citations

Addictive Drugs: The Cigarette Experience

1992 • 88 citations

NICOTINE ADDICTION AND TREATMENT

1996 • 84 citations

Chapter 7: Nicotinic receptors in mammalian brain: localization and relation to cholinergic innervation

1993 • 80 citations

Acetylcholine Receptors: Too Many Channels, Too Few Functions

1995 • 73 citations

Cellular distribution of nicotinic acetylcholine receptor subunit mRNAs in the human cerebral cortex as revealed by non-isotopic in situ hybridization

1994 • 72 citations

Mood, major depression, and fluoxetine response in cigarette smokers

1995 • 72 citations

Platelet monoamine oxidase: Low activity in cigarette smokers

1987 • 70 citations

Smoking habit and psychometric scores: a community study.

1978 • 57 citations

Tobacco Smoking and Nicotine Neuropsychopharmacology: Some Future Research Directions

1998 • 57 citations

Depression After Smoking Cessation

1996 • 56 citations

Brain Reward Circuits in Alcoholism

1999 • 51 citations

Effects of cigarette smoking and 12-h abstention on working memory during a serial-probe recognition task

1998 • 49 citations

Shaking Out the Cause of Addiction

1996 • 49 citations

Effects of central and peripheral nicotinic blockade on human nicotine discrimination

1999 • 48 citations

Depression following smoking cessation in women

1996 • 45 citations

Effects of doxepin on withdrawal symptoms in smoking cessation

1990 • 41 citations

Depression and Smoking Cessation in Older Adults: A Longitudinal Study

1993 • 40 citations

Does nicotine improve cognitive function?

1994 • 39 citations

Effects of transdermal nicotine delivery on measures of acute nicotine withdrawal.

1996 • 38 citations

Effects of fluoxetine on weight gain and food intake in smokers who reduce nicotine intake

1991 • 36 citations

Weight suppression and weight rebound in ex-smokers treated with fluoxetine.

1999 • 35 citations

The effects of cigarette smoking on overnight performance

1998 • 30 citations

Predictors of success in a smoking cessation clinic

1996 • 26 citations

Comparison of the effects of nicotine on a fixed rate and a subject-paced version of the rapid information processing task

1995 • 24 citations

Nicotine and cotinine replacement when nicotine nasal spray is used to quit smoking

1998 • 10 citations