Continous intracerebroventricular infusion of dopamine and dopamine agonists through a totally implanted drug delivery system in animal models of Parkinson's disease

3,4-Dihydroxyphenylalanine and 5-Hydroxytryptophan as Reserpine Antagonists

1957 • 1,233 citations

Reduction of cortical dopamine, noradrenaline, serotonin and their metabolites in Parkinson's disease

1983 • 712 citations

Brain receptors for antipsychotic drugs and dopamine: direct binding assays.

1975 • 695 citations

The occurrence, distribution and physiological role of catecholamines in the nervous system.

1959 • 665 citations

SUCCESS AND PROBLEMS OF LONG-TERM LEVODOPA THERAPY IN PARKINSON'S DISEASE

1977 • 585 citations

Locus ceruleus lesions and eosinophilic inclusions in MPTP‐treated monkeys

1986 • 347 citations

Analysis of the clinical problems in parkinsonism and the complications of long‐term levodopa therapy

1979 • 319 citations

Effect of ethanol on the hydroxylation of tyrosine and tryptophan in rat brain in vivo

1973 • 312 citations

Control of on/off phenomenon by continuous intravenous infusion of levodopa

1984 • 226 citations

Dopamine deficiency in the cerebral cortex in Parkinson disease

1982 • 179 citations

Levodopa pharmacokinetics and pharmacodynamics in fluctuating parkinsonian patients

1986 • 149 citations

COMPLICATED RESPONSE FLUCTUATIONS IN PARKINSON'S DISEASE: RESPONSE TO INTRAVENOUS INFUSION OF LEVODOPA

1982 • 131 citations

Considerations in the management of parkinsonism

1978 • 89 citations

3‐O‐ methyldopa blocks dopa metabolism in rat corpus striatum

1982 • 81 citations

Intravenous lisuride corrects oscillations of motor performance in Parkinson's disease

1986 • 55 citations

3‐O‐Methyldopa inhibits rotations induced by levodopa in rats after unilateral destruction of the nigrostriatal pathway

1982 • 49 citations

Treatment of Parkinson's disease: Problems with a progressing disease

1981 • 48 citations

Levodopa methyl ester treatment of Parkinson's disease

1987 • 47 citations

Repeated Levodopa Infusions in Fluctuating Parkinsonʼs Disease

1986 • 43 citations

Pharmacokinetics of L-dopa in patients with Parkinson's disease.

1987 • 31 citations

Differentiation of dopamine agonists using drug-induced rotation in rats with unilateral or bilateral 6-hydroxydopamine destruction of ascending dopamine pathways

1983 • 25 citations

Relatively high levels of dopamine in nucleus accumbens of levodopa treated patients with Parkinson's disease

1982 • 21 citations

STUDIES ON THE OXIDATION OF DOPAMINE TO MELANIN BY RAT BRAIN.

1964 • 7 citations

The effect of single and repeated administration of bromocriptine on monoamine metabolism in rat brain and [³H]spiroperidol binding to striatal membranes

1986 • 6 citations

Genetic Relationships among the Inhabitants of Nine Mediterranean Countries

1986 • 4 citations