Treatment of Parkinson's disease: Problems with a progressing disease

Parkinsonism

1967 • 11,463 citations

Overdependence on degraded gist memory in Alzheimer's disease.

2006 • 4,533 citations

"ON-OFF" EFFECTS IN PATIENTS WITH PARKINSON'S DISEASE ON CHRONIC LEVODOPA THERAPY

1976 • 651 citations

Receptor basis for dopaminergic supersensitivity in Parkinson's disease

1978 • 447 citations

Dementia in Parkinson disease

1979 • 384 citations

Advances in Neurology. Vol. 2

1974 • 364 citations

Dementia in Parkinson disease

1979 • 341 citations

Analysis of the clinical problems in parkinsonism and the complications of long‐term levodopa therapy

1979 • 319 citations

Bromocriptine in Parkinsonism

1974 • 311 citations

On‐off response

1975 • 273 citations

Neurotransmitter receptor alterations in Parkinson's disease

1977 • 251 citations

“On‐off” phenomenon with levodopa therapy in parkinsonism

1974 • 232 citations

Advances in Biochemical Psychopharmacology vol 1.

1970 • 188 citations

Five Years' Treatment of Parkinson's Disease with Levodopa

1975 • 173 citations

Treatment of Parkinson's Disease with Aporphines

1976 • 167 citations

The pathology of Parkinsonism: a comparison of degenerations in cerebral cortex and brainstem.

1974 • 137 citations

LONG-TERM TREATMENT OF PARKINSONISM WITH BROMOCRIPTINE

1978 • 135 citations

Patterns of clinical response and plasma dopa levels in Parkinson's disease

1975 • 111 citations

The clinical physiology of side effects in long-term L-DOPA therapy.

1974 • 96 citations

Overview of present day treatment of Parkinson's disease

1978 • 87 citations

Mortality of patients with parkinson's disease treated with levodopa

1977 • 79 citations

Brain Catecholamines and Their Metabolites in Parkinsonian Patients

1973 • 75 citations

Recent observations on the clinical pharmacology of (-)deprenyl

1978 • 74 citations

Brain-noradrenaline and 3-methoxy-4-hydroxyphenylglycol in Parkinson's syndrome

1977 • 73 citations

Bromocriptine treatment in Parkinson's disease.

1976 • 73 citations

Plasma dopa concentrations and the “on‐off” effect after chronic treatment of Parkinson's disease

1974 • 72 citations

Present mortality in Parkinson's disease: the ratio of observed to expected deaths with a method to calculate expected deaths

1976 • 69 citations

Cerebral atrophy in Parkinsonism

1968 • 69 citations

Mortality among Parkinson Patients Treated with L-Dopa Combined with a Decarboxylase Inhibitor

1976 • 64 citations

Levodopa in Parkinson disease: A long‐term appraisal of mortality

1978 • 62 citations

Studies with bromocriptine Part 1. “On‐off” phenomena

1976 • 58 citations

Effects of L-dopa metabolites at a dopamine receptor suggest a basis for ‘on-off’ effect in Parkinson's disease

1975 • 57 citations

The antiparkinsonian efficacy of bromocriptine

1976 • 53 citations

Viral meningoencephalitis and head injury

1978 • 46 citations

The role of bromocriptine in the treatment of parkinsonism

1979 • 45 citations

Recent advances in research on Parkinsonism.

1978 • 44 citations

The Postnatal Development of the Human Cerebral Cortex

1960 • 39 citations

Recent advances in research on Parkinsonism.

1978 • 37 citations

The <scp>L</scp>‐dopa on‐off effect in parkinson disease: Treatment by transient drug withdrawal and dopamine receptor resensitization

1978 • 33 citations

The significance of cerebral atrophy for the symptomatology of Parkinson's disease

1979 • 28 citations

Dopamine in thelimbic regions of the human brain: normal and abnormal.

1977 • 27 citations

"On-Off" Phenomena Related to High Plasma Levodopa

1973 • 27 citations

BROMOCRIPTINE VERSUS PLACEBO IN LEVODOPA TREATED PATIENTS WITH PARKINSON'S DISEASE

2009 • 27 citations

Genetic Distance Analysis of Twenty-Two South American Indian Populations

1975 • 27 citations

Bromocryptine in Levodopa Response-Losing Parkinsonism

1978 • 25 citations

Permanent Dementia in Idiopathic Parkinsonism Treated With Levodopa

1973 • 21 citations

Brain dopamine receptor stimulation and the relief of parkinsonism: Relationship between bromocriptine and levodopa

1978 • 18 citations

Long-Term Responses of Parkinson’s Disease to Levodopa Therapy

1980 • 17 citations

RECENT ADVANCES IN THE TREATMENT OF PARKINSON'S DISEASE

1980 • 16 citations

Brain Dopamine Turnover and the Relief of Parkinsonism

1977 • 13 citations

Treatment of Parkinson's Disease With Lergotrile Mesylate

1977 • 11 citations

A New Anaesthetic

1880 • 2 citations