Effects of a Number of Classes of 50S Inhibitors on Stop Codon Readthrough during Protein Synthesis

The Molecular Basis of Antibiotic Action

1981 • 1,237 citations

Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

2001 • 1,011 citations

The Structures of Four Macrolide Antibiotics Bound to the Large Ribosomal Subunit

2002 • 553 citations

The quinolones: decades of development and use

2003 • 491 citations

The Mechanism of Action of Macrolides, Lincosamides and Streptogramin B Reveals the Nascent Peptide Exit Path in the Ribosome

2003 • 429 citations

Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit

2003 • 383 citations

The Active Site of the Ribosome Is Composed of Two Layers of Conserved Nucleotides with Distinct Roles in Peptide Bond Formation and Peptide Release

2004 • 341 citations

The ribosome as an entropy trap

2004 • 328 citations

A cryo-electron microscopic study of ribosome-bound termination factor RF2

2003 • 235 citations

Structural Basis for the Antibiotic Activity of Ketolides and Azalides

2003 • 228 citations

A novel inhibitor of multidrug efflux pumps in Staphylococcus aureus

2002 • 203 citations

Structure of the Escherichia coli ribosomal termination complex with release factor 2

2003 • 199 citations

Structural insight into the role of the ribosomal tunnel in cellular regulation

2003 • 177 citations

Oxazolidinone Resistance Mutations in 23S rRNA of Escherichia coli Reveal the Central Region of Domain V as the Primary Site of Drug Action

2000 • 164 citations

Cooperative and Antagonistic Interactions of Peptidyl‐tRNA and Antibiotics with Bacterial Ribosomes

1977 • 114 citations

The Protein Synthesis Inhibitors, Oxazolidinones and Chloramphenicol, Cause Extensive Translational Inaccuracy in Vivo

2002 • 96 citations

A ribosomal ambiguity mulation in the 530 loop ofE.coli16S rRNA

1992 • 90 citations

Antibiotics as Probes of Ribosome Structure: Binding of Chloramphenicol and Erythromycin to Polyribosomes; Effect of Other Antibiotics

1974 • 52 citations

Partial release of AcPhe‐Phe‐tRNA from ribosomes during poly(U)‐dependent poly(Phe) synthesis and the effects of chloramphenicol

1990 • 39 citations

Induction of translational errors (misreading) by tuberactinomycins and capreomycins

1980 • 25 citations