Analysis of cellular interactions in limiting dilution cultures

Minuit - a system for function minimization and analysis of the parameter errors and correlations

1975 • 2,979 citations

The evaluation of limiting dilution assays

1982 • 458 citations

A THREE-CELL INTERACTION REQUIRED FOR THE INDUCTION OF THE PRIMARY IMMUNE RESPONSE in vitro

1968 • 237 citations

Age-associated decline in precursor frequency for different T cell-mediated reactions, with preservation of helper or cytotoxic effect per precursor cell.

1984 • 140 citations

Differential tyrosine-specific protein phosphorylation in mouse T lymphocyte subsets. Effect of age.

1993 • 63 citations

Accumulation of hyporesponsive, calcium extruding memory T cells as a key feature of age-dependent immune dysfunction

1991 • 54 citations

Quantitative studies on T cell diversity. II. Determination of the frequencies and Lyt phenotypes of two types of precursor cells for alloreactive cytotoxic T cells in polyclonally and specifically activated splenic T cells.

1981 • 53 citations

Positive and Negative Allogeneic Effects Mediated by MLR-Primed Lymphocytes: Quantitation by Limiting Dilution Analysis

1978 • 40 citations

Quantitative studies on T cell diversity. IV. Mathematical analysis of multiple limiting populations of effector and suppressor T cells.

1983 • 39 citations

Quantitative studies on T cell diversity. III. Limiting dilution analysis of precursor cells for T helper cells reactive to xenogeneic erythrocytes.

1982 • 35 citations

Antagonistic interactions among T cell subsets of old mice revealed by limiting dilution analysis.

1995 • 23 citations

Limiting dilution analysis of the frequencies of helper and suppressor T cells in untreated and TNP-treated BALB/c mice: response as a consequence of perturbation of a stable steady state.

1985 • 16 citations

Analysis of the limiting-dilution assay used for estimating frequencies of immunocompetent units

1974 • 13 citations

Activation/suppression of the immune response in vitro by antigen and dextran sulfate I. Analysis by limiting dilution methods

1985 • 9 citations

Comparative Study of Immunomodulatory Properties of Muramyl Peptides On Immune System Cells of Yg and Old Mice

1994 • 9 citations

Regulatory cellular interactions in the primary mixed lymphocyte reaction

1995 • 8 citations

Frequencies and Interactions of Regulatory T Cells. I. The Balance between Help and Suppression Regulates the Primary Immune Response to Keyhole Limpet Hemocy

1989 • 7 citations

Direct effect of cyclosporin A on CD8+ T lymphocytes in a primary mixed lymphocyte reaction

1990 • 5 citations

A novel autoregulatory cytokine is required for the regulation of autoaggressive responses

1990 • 2 citations