Direct effect of cyclosporin A on CD8+ T lymphocytes in a primary mixed lymphocyte reaction

Effects of the new anti-lymphocytic peptide cyclosporin A in animals.

1977 • 710 citations

Cyclosporin A mediates immunosuppression of primary cytotoxic T cell responses by impairing the release of interleukin 1 and interleukin 2

1981 • 632 citations

The Effects of Cyclosporin A on the Immune System

1985 • 442 citations

Induction of Interleukin 2 Messenger RNA Inhibited by Cyclosporin A

1984 • 404 citations

Dexamethasone-mediated inhibition of human T cell growth factor and gamma-interferon messenger RNA.

1984 • 390 citations

Cyclosporin A and dexamethasone suppress T cell responses by selectively acting at distinct sites of the triggering process.

1980 • 351 citations

Lymphokine and nonlymphokine mRNA levels in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A.

1986 • 293 citations

Effect of cyclosporin A on human lymphocyte responses in vitro. I. CsA allows for the expression of alloantigen-activated suppressor cells while preferentially inhibiting the induction of cytolytic effector lymphocytes in MLR.

1980 • 239 citations

Quantitation and Cloning of Cytolytic T Lymphocytes and their Precursors

1980 • 213 citations

Effect of cyclosporin A and dexamethasone on interleukin 2 receptor gene expression.

1986 • 171 citations

The Efficient Design of Transplantable Tumour Assays

1963 • 147 citations

Quantitative analysis of the 51Cr release cytotoxicity assay for cytotoxic lymphocytes

1974 • 134 citations

Immunosuppressive effects of cyclosporin A on cloned T cells.

1986 • 134 citations

SPARING OF SUPPRESSOR CELLS

1984 • 118 citations

The cyclosporins inhibit lymphocyte activation at more than one site.

1987 • 115 citations

Cyclosporin A does not prevent expression of Tac antigen, a probable TCGF receptor molecule, on mitogen-stimulated human T cells.

1983 • 105 citations

Quantitative Studies of the Activation of Cytotoxic Lymphocyte Precursor Cells

1977 • 100 citations

Differential effect of cyclosporin A on the expression of T and B lymphocyte activation antigens.

1984 • 91 citations

Effect of cyclosporin A on human lymphocyte responses in vitro. II. Induction of specific alloantigen unresponsiveness mediated by a nylon wool adherent suppressor cell.

1981 • 77 citations

The influence of cyclosporin A on cell-mediated immunity.

1988 • 51 citations

Evidence for the presence of suppressor T lymphocytes in animals treated with cyclosporin A.

1982 • 48 citations

EFFECT OF INTERLEUKIN 2 ON THE IMMUNOSUPPRESSIVE ACTION OF CYCLOSPORINE

1985 • 47 citations

Cyclosporine blocks the activation of antigen-dependent cytotoxic T lymphocytes directly by an IL-2-independent mechanism.

1988 • 28 citations

FREQUENCY ANALYSIS OF CYCLOSPORINE-SENSITIVE CYTOTOXIC T LYMPHOCYTE PRECURSORS

1984 • 23 citations

Inhibition of the production of a soluble helper mediator by cyclosporin A results in the failure to generate alloreactive cytolytic cells in mixed-lymphocyte culture

1983 • 16 citations

Growth‐dependent variation of major histocompatibility complex (MHC) restriction and expression of Ly‐2 and CD3/α/βT cell receptor in cloned cytotoxic T cells

1988 • 10 citations