Site-directed Mutagenesis of P2U Purinoceptors

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Nomenclature and classification of purinoceptors.

1994 • 1,569 citations

Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides

1993 • 1,259 citations

Influence of proline residues on protein conformation

1991 • 1,125 citations

STRUCTURE AND FUNCTION OF G PROTEIN-COUPLED RECEPTORS

1994 • 1,070 citations

Sequence Alignment of the G-Protein Coupled Receptor Superfamily

1992 • 847 citations

Expression cloning of an ATP receptor from mouse neuroblastoma cells.

1993 • 587 citations

Cloning and functional expression of a brain G‐protein‐coupled ATP receptor

1993 • 545 citations

Activation by Extracellular Nucleotides of Chloride Secretion in the Airway Epithelia of Patients with Cystic Fibrosis

1991 • 495 citations

Cloning and expression of a human P2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy.

1994 • 410 citations

Three-dimensional models of neurotransmitter G-binding protein-coupled receptors.

1991 • 330 citations

G protein-coupled receptors for ATP and other nucleotides: a new receptor family

1994 • 252 citations

Proline residues in transmembrane helixes: structural or dynamic role?

1991 • 240 citations

Extracellular nucleotides mediate Ca2+ fluxes in J774 macrophages by two distinct mechanisms.

1988 • 189 citations

Expression of a cloned P2Y purinergic receptor that couples to phospholipase C.

1994 • 177 citations

P2 purinoceptors on vascular endotheliai cells: physiological significance and transduction mechanisms

1990 • 160 citations

Cloning, expression, and characterization of the unique bovine A1 adenosine receptor. Studies on the ligand binding site by site-directed mutagenesis.

1992 • 144 citations

Chloride secretory response to extracellular ATP in human normal and cystic fibrosis nasal epithelia

1992 • 134 citations

Functional expression and photoaffinity labeling of a cloned P2U purinergic receptor.

1993 • 106 citations

Analysis and refinement of criteria for predicting the structure and relative orientations of transmembranal helical domains

1992 • 98 citations

Regulation of the neurotensin receptor and intracellular calcium mobilization in HT29 cells.

1990 • 84 citations

Structural specificity of nucleotides for insulin secretory action from the isolated perfused rat pancreas

1979 • 79 citations

Mechanisms by which extracellular ATP and UTP stimulate the release of prostacyclin from bovine pulmonary artery endothelial cells

1992 • 74 citations

A nucleotide receptor in vascular endothelial cells is specifically activated by the fully ionized forms of ATP and UTP

1992 • 55 citations

Calcium responses elicited by nucleotides in macrophages. Interaction between two receptor subtypes.

1993 • 52 citations

Evidence that a form of ATP uncomplexed with divalent cations is the ligand of P_2y and nucleotide/P_2u receptors on aortic endothelial cells

1993 • 27 citations

Increased levels of c-fos and c-myc mRNA in ATP-stimulated endothelial cells

1990 • 22 citations