Single Dose of OOCH Improves Mucosal T Helper Type 1/T Helper Type 2 Cytokine Balance and Prevents Experimental Colitis in the Presence of Vα14 Natural Killer T Cells in Mice

Inflammatory Bowel Disease

2002 • 3,038 citations

CD1d-Restricted and TCR-Mediated Activation of V _α 14 NKT Cells by Glycosylceramides

1997 • 2,370 citations

Treatment of Murine Colitis by Lactococcus lactis Secreting Interleukin-10

2000 • 1,406 citations

Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?

2002 • 1,343 citations

Requirement for V _α 14 NKT Cells in IL-12-Mediated Rejection of Tumors

1997 • 1,226 citations

Chronic Intestinal Inflammatory Condition Generates IL-10-Producing Regulatory B Cell Subset Characterized by CD1d Upregulation

2002 • 929 citations

A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells

2001 • 864 citations

Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis

2004 • 746 citations

The Regulatory Role of Vα14 NKT Cells in Innate and Acquired Immune Response

2003 • 673 citations

Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes

1998 • 642 citations

Oxazolone Colitis, a Th2 Colitis Model Resembling Ulcerative Colitis, Is Mediated by IL-13-Producing NK-T Cells

2002 • 639 citations

The Natural Killer T (NKT) Cell Ligand α-Galactosylceramide Demonstrates Its Immunopotentiating Effect by Inducing Interleukin (IL)-12 Production by Dendritic Cells and IL-12 Receptor Expression on NKT Cells

1999 • 624 citations

Activation of natural killer T cells by α-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

2001 • 605 citations

The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice

2001 • 556 citations

Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14 NKT cells

1998 • 474 citations

α/β–T Cell Receptor (TCR)+CD4−CD8− (NKT) Thymocytes Prevent Insulin-dependent Diabetes Mellitus in Nonobese Diabetic (NOD)/Lt Mice by the Influence of Interleukin (IL)-4 and/or IL-10

1998 • 473 citations

IL-1β-converting enzyme (caspase-1) in intestinal inflammation

2001 • 408 citations

Agelasphins, novel antitumor and immunostimulatory cerebrosides from the marine sponge Agelas mauritianus

1994 • 389 citations

Selective ability of mouse CD1 to present glycolipids: alpha-galactosylceramide specifically stimulates V alpha 14+ NK T lymphocytes.

1998 • 383 citations

Early quantitative and functional deficiency of NK1⁺‐like thymocytes in the NOD mouse

1996 • 359 citations

Interferon gamma production by natural killer (NK) cells and NK1.1+ T cells upon NKR-P1 cross-linking.

1996 • 349 citations

Selective Ability of Mouse CD1 to Present Glycolipids: α-Galactosylceramide Specifically Stimulates Vα14+ NK T Lymphocytes

1998 • 319 citations

Immunization with α-galactosylceramide polarizes CD1-reactive NK T cells towards Th2 cytokine synthesis

1999 • 306 citations

Interferon-gamma (IFN-γ)- and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice

1999 • 298 citations

Cultured NK1.1+ CD4+ T cells produce large amounts of IL-4 and IFN-gamma upon activation by anti-CD3 or CD1.

1997 • 291 citations

Selective reduction of V alpha 14+ NK T cells associated with disease development in autoimmune-prone mice.

1996 • 290 citations

Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity

2003 • 278 citations

Cutting edge: inhibition of experimental tumor metastasis by dendritic cells pulsed with alpha-galactosylceramide.

1999 • 264 citations

α-Galactosylceramide-activated Vα14 natural killer T cells mediate protection against murine malaria

2000 • 261 citations

Mice with a Selective Deletion of the CC Chemokine Receptors 5 or 2 Are Protected from Dextran Sodium Sulfate-Mediated Colitis: Lack of CC Chemokine Receptor 5 Expression Results in a NK1.1+ Lymphocyte-Associated Th2-Type Immune Response in the Intestine

2000 • 253 citations

Agelasphins, novel α-galactosylceramides from the marine sponge Agelas mauritianus

1993 • 243 citations

Cutting Edge: Inhibition of Experimental Tumor Metastasis by Dendritic Cells Pulsed with α-Galactosylceramide

1999 • 230 citations

CD1-dependent dendritic cell instruction

2002 • 215 citations

Activation of natural killer T cells by α-galactosylceramide in the presence of CD1d provides protection against colitis in mice

2000 • 210 citations

Ligation of intestinal epithelial CD1d induces bioactive IL-10: Critical role of the cytoplasmic tail in autocrine signaling

1999 • 179 citations

Histological Analysis of Murine Colitis Induced by Dextran Sulfate Sodium of Different Molecular Weights.

2000 • 176 citations

Liver NK1.1+ CD4+ alpha beta T cells activated by IL-12 as a major effector in inhibition of experimental tumor metastasis.

1996 • 175 citations

Tissue-Specific Recognition of Mouse CD1 Molecules

1998 • 158 citations

Activation of Vα14⁺Natural Killer T Cells by α-Galactosylceramide Results in Development of Th1 Response and Local Host Resistance in Mice Infected withCryptococcus neoformans

2001 • 150 citations

Understanding the function of CD1-restricted T cells

2003 • 123 citations

Costimulation-Dependent Modulation of Experimental Autoimmune Encephalomyelitis by Ligand Stimulation of Vα14 NK T Cells

2001 • 123 citations

Colonic lamina propria dendritic cells in mice with CD4⁺ T cell‐induced colitis

2003 • 113 citations

IL-4-producing NK T cells are biased towards IFN-γ production by IL-12. Influence of the microenvironment on the functional capacities of NK T cells

1998 • 93 citations

Tissue distribution, regulation and intracellular localization of murine CD1 molecules

1998 • 90 citations

腸管上皮CD1dの架橋は生物活性型IL‐10を誘導する オートクリンシグナル伝達における細胞質領域末端の重要な役割

1999 • 79 citations

IL-4-Producing NK1.1+ T Cells Are Resistant to Glucocorticoid-Induced Apoptosis: Implications for the Th1/Th2 Balance

1998 • 65 citations

Regulation of mucosal immune responses by recombinant interleukin 10 produced by intestinal epithelial cells in mice

2002 • 61 citations

Dextran sulphate sodium-induced colitis is ameliorated in interleukin 4 deficient mice

2001 • 54 citations

NKT cell subsets in infection and inflammation

2003 • 48 citations

A synthetic mimetic of CD4 is able to suppress disease in a rodent model of immune colitis

1999 • 45 citations

NK1.1⁺ T cells from IL-7-deficient mice have a normal distribution and selection but exhibit impaired cytokine production

1996 • 44 citations

Bacille Calmette Guérin and interleukin‐12 down‐modulate interleukin‐4‐producing CD4⁺ NK1⁺ T lymphocytes

1997 • 42 citations

Natural Killer T Cells as Targets for Therapeutic Intervention in Autoimmune Diseases

2003 • 41 citations

Invariant Valpha14 NKT lymphocytes: a double-edged immuno-regulatory T cell population.

2003 • 25 citations

Requirement of IL-7 for IL-4-producing potential of MHC class I- selected CD4-CD8-TCR alpha beta+ thymocytes

1997 • 20 citations

The multiple roles of major histocompatibility complex class-I-like molecules in mucosal immune function

2001 • 17 citations

Rat T-cell receptor TRAV11 (V?14) genes: further evidence of extensive multiplicity with homogeneous CDR1 and diversified CDR2 by genomic contig and cDNA analysis

2004 • 8 citations

CD1d-Restricted T Cell Pathways at the Epithelial-Lymphocyte-Luminal Interface

2004 • 2 citations