Analysis of the T-cell receptor beta-chainvariable-region (V beta) repertoire in monozygotic twins discordant for humanimmunodeficiency virus: evidence for perturbations of specific V beta segmentsin CD4+ T cells of the virus-positive twins.

The Immunopathogenesis of Human Immunodeficiency Virus Infection

1993 • 1,194 citations

The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice

1989 • 1,095 citations

Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex

1988 • 1,036 citations

Interaction of Staphylococcus aureus toxin "superantigens" with human T cells.

1989 • 1,000 citations

Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals.

1992 • 907 citations

Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity

1990 • 904 citations

T-cell receptor Vβ use predicts reactivity and tolerance to Mlsa- encoded antigens

1988 • 901 citations

Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity

1986 • 804 citations

Vβ-Specific Stimulation of Human T Cells by Staphylococcal Toxins

1989 • 711 citations

Temporal fluctuations in HIV quasispecies in vivo are not reflected by sequential HIV isolations

1989 • 655 citations

Evidence for the Effects of a Superantigen in Rheumatoid Arthritis

1991 • 632 citations

Superantigens and Their Potential Role in Human Disease

1993 • 620 citations

Induction of CD4-dependent cell fusion by the HTLV-III/LAV envelope glycoprotein

1986 • 593 citations

Genetic Variation in HTLV-III/LAV Over Time in Patients with AIDS or at Risk for AIDS

1986 • 570 citations

The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens

1988 • 491 citations

Clonal anergy induced in mature Vβ6+ T lymphocytes on immunizing Mls-1b mice with Mls-1a expressing cells

1989 • 462 citations

T cell stimulation by staphylococcal enterotoxins. Clonally variable response and requirement for major histocompatibility complex class II molecules on accessory or target cells.

1988 • 427 citations

A superantigen encoded in the open reading frame of the 3′ long terminal repeat of mouse mammary tumour virus

1991 • 394 citations

Selective expansion of T cells expressing V beta 2 in toxic shock syndrome.

1990 • 359 citations

A maternally inherited superantigen encoded by a mammary tumour virus

1991 • 335 citations

The MHC molecule I-E is necessary but not sufficient for the clonal deletion of V beta 11-bearing T cells.

1989 • 331 citations

Selective Depletion in HIV Infection of T Cells that Bear Specific T Cell Receptor V _β Sequences

1991 • 322 citations

Linkage of Mls genes to endogenous mammary tumour viruses of inbred mice

1991 • 307 citations

Genes encoding ligands for deletion of Vβ11 T cells cosegregate with mammary tumour virus genomes

1991 • 297 citations

T cells can present antigens such as HIV gp120 targeted to their own surface molecules

1988 • 294 citations

An endogenous retrovirus mediating deletion of αβ T cells?

1991 • 278 citations

Clonal deletion of V β814-bearing T cells in mice transgenic for mammary tumour virus

1991 • 277 citations

Identification of the region of T cell receptor β chain that interacts with the self-superantigen MIs-1a

1990 • 242 citations

Transgenic mouse mammary tumor virus superantigen expression prevents viral infection

1992 • 223 citations

Common epitope in human immunodeficiency virus (HIV) I-GP41 and HLA class II elicits immunosuppressive autoantibodies capable of contributing to immune dysfunction in HIV I infected individuals.

1990 • 197 citations

Requirement for Cotolerogenic Gene Products in the Clonal Deletion of I-E Reactive T Cells

1990 • 193 citations

Superantigen-induced immune stimulation amplifies mouse mammary tumor virus infection and allows virus transmission

1993 • 189 citations

T cell receptor V-segment frequencies in peripheral blood T cells correlate with human leukocyte antigen type.

1991 • 166 citations

Superantigen implicated in dependence of HIV-1 replication in T cells on TCR V β expression

1992 • 152 citations

Defective clonogenic potential of CD8+ T lymphocytes in patients with AIDS. Expansion in vivo of a nonclonogenic CD3+CD8+DR+CD25- T cell population.

1990 • 131 citations

Differential usage of T cell receptor V gene segments in CD4+ and CD8+ subsets of T lymphocytes in monozygotic twins.

1993 • 124 citations

Vβ17 gene polymorphism in wild-derived mouse strains: Two amino acid substitutions in the Vβ17 region greatly alter T cell receptor specificity

1990 • 122 citations

Human T cells respond to mouse mammary tumor virus-encoded superantigen: V beta restriction and conserved evolutionary features.

1993 • 73 citations

T-cell antigen receptor Vβ subsets are not preferentially deleted in AIDS

1993 • 61 citations

Conserved T-cell receptor repertoire in simian immunodeficiency virus-infected rhesus monkeys.

1993 • 52 citations

The T cell receptor Vβ repertoire in HIV-1 infection and disease

1993 • 48 citations

HIV infection leads to differential expression of T-cell receptor Vβ genes in CD4+ and CD8+ T cells

1993 • 42 citations

Studies on the mechanism of stimulation of T cells by the Mycoplasma arthritidis-derived mitogen. Role of class II IE molecules.

1987 • 41 citations

A method for production of antibodies to human T-cell receptor beta-chain variable regions.

1991 • 33 citations

Generation of monoclonal antibodies against soluble human T cell receptor polypeptides

1991 • 25 citations

Analysis of Mlsc genetics. A novel instance of genetic redundancy.

1989 • 22 citations