Heterogeneity of the TCR Repertoire in Synovial Fluid T Lymphocytes Responding to BCG in a Patient with Early Rheumatoid Arthritis

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetii

2007 • 11,720 citations

The shared epitope hypothesis. an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis

1987 • 2,539 citations

Association of the B-Cell Alloantigen DRw4 with Rheumatoid Arthritis

1978 • 1,170 citations

The T Lymphocyte in Experimental Allergic Encephalomyelitis

1990 • 1,005 citations

Molecular mimicry and autoimmune disease

1987 • 943 citations

Development of Arthritis, Periarthritis and Periostitis in Rats Given Adjuvants.

1956 • 847 citations

Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis

1988 • 838 citations

Evidence for the Effects of a Superantigen in Rheumatoid Arthritis

1991 • 632 citations

Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy

1988 • 555 citations

Primary structure of a human mitochondrial protein homologous to the bacterial and plant chaperonins and to the 65-kilodalton mycobacterial antigen.

1989 • 492 citations

Stress proteins are immune targets in leprosy and tuberculosis.

1988 • 446 citations

Lines of T Lymphocytes Induce or Vaccinate Against Autoimmune Arthritis

1983 • 418 citations

Rapid and quantitative preparation of cytoplasmic RNA from small numbers of cells

1988 • 406 citations

SYNOVIAL FLUID T CELL REACTIVITY AGAINST 65 kD HEAT SHOCK PROTEIN OF MYCOBACTERIA IN EARLY CHRONIC ARTHRITIS

1988 • 311 citations

Arthritis induced in rats by cloned T lymphocytes responsive to mycobacteria but not to collagen type II.

1984 • 296 citations

Clonal dominance among T-lymphocyte infiltrates in arthritis.

1988 • 268 citations

T lymphocytes from healthy individuals with specificity to self-epitopes shared by the mycobacterial and human 65-kilodalton heat shock protein.

1989 • 237 citations

A simple new method for using antigens separated by polyacrylamide gel electrophoresis to stimulate lymphocytes in vitro after converting bands cut from Western blots into antigen-bearing particles

1987 • 231 citations

Treatment of Intractable Rheumatoid Arthritis with Total Lymphoid Irradiation

1981 • 210 citations

A heat shock operon in Coxiella burnetti produces a major antigen homologous to a protein in both mycobacteria and Escherichia coli

1988 • 198 citations

Restricted expression of T cell receptor V_β but not V_α genes in rheumatoid arthritis

1991 • 189 citations

In vitro responses to a 65-kilodalton mycobacterial protein by synovial T cells from inflammatory arthritis patients.

1989 • 175 citations

The T-cell-receptor repertoire in the synovial fluid of a patient with rheumatoid arthritis is polyclonal.

1991 • 169 citations

Clinical and Immunologic Effects of Fractionated Total Lymphoid Irradiation in Refractory Rheumatoid Arthritis

1981 • 167 citations

Prevention and treatment of murine experimental allergic encephalomyelitis with T cell receptor V beta-specific antibodies.

1990 • 164 citations

Activated T cells in vivo and in vitro: divergence in expression of Tac and Ia antigens in the nonblastoid small T cells of inflammation and normal T cells activated in vitro.

1984 • 160 citations

T lymphocyte clones illuminate pathogenesis and affect therapy of experimental arthritis

1985 • 155 citations

Analysis of T cell receptor beta chains in Lewis rats with experimental allergic encephalomyelitis: conserved complementarity determining region 3.

1991 • 127 citations

Peptide recognition, T cell receptor usage and HLA restriction elements of human heat‐shock protein (hsp) 60 and mycobacterial 65‐kDa hsp‐reactive T cell clones from rheumatoid synovial fluid

1992 • 118 citations

Clonal heterogeneity of synovial fluid T lymphocytes from patients with rheumatoid arthritis.

1989 • 108 citations

T cell receptor V beta gene usage in a human alloreactive response. Shared structural features among HLA-B27-specific T cell clones.

1990 • 94 citations

Structure of t cell antigen receptor β chain in synovial fluid cells from patients with rheumatoid arthritis

1988 • 78 citations

Efficacy of Total Lymphoid Irradiation in Intractable Rheumatoid Arthritis

1985 • 78 citations

A Minority of Patients with Rheumatoid Arthritis Show a Dominant Rearrangement of T‐Cell Receptor β Chain Genes in Synovial Lymphocytes

1987 • 77 citations

Tγδ Cells in Juvenile Rheumatoid Arthritis and Rheumatoid Arthritis

1990 • 68 citations

In Vitro Mitogen Stimulation of Synovial Fluid Lymphocytes from Rheumatoid Arthritis and Juvenile Rheumatoid Arthritis Patients: Dissociation between the Response to Antigens and Polyclonal Mitogens

1978 • 65 citations

Expression of Activation Antigens on T Cells in Rheumatoid Arthritis Patients

1990 • 63 citations

Sustained improvement of intractable rheumatoid arthritis after total lymphoid irradiation

1983 • 62 citations

Dominant T‐Cell Receptor β‐Chain Gene Rearrangements Indicate Clonal Expansion in the Rheumatoid Joint

1990 • 57 citations

High antigen reactivity in mononuclear cells from sites of chronic inflammation

1990 • 56 citations

Evidence of an Activated T‐Cell System with Augmented Turnover of Interleukin 2 in Rheumatoid Arthritis

1987 • 49 citations

T cell antigen receptors in autoimmunity.

1988 • 46 citations

Mycobacteria and human heat shock protein—specific cytotoxic t lymphocytes in rheumatoid synovial inflammation

1992 • 43 citations