Small DNA Deletions Creating Avirulence in Streptococcus pyogenes

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

1982 • 6,153 citations

The isolation of structural genes from libraries of eucaryotic DNA

1978 • 1,877 citations

Current Knowledge of Type-Specific M Antigens of Group A Streptococci

1962 • 793 citations

[19] In Vitro packaging of λ and cosmid DNA

1979 • 537 citations

THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HÆMOLYTICUS

1928 • 373 citations

DIFFERENTIATION OF GROUP A STREPTOCOCCI WITH A COMMON R ANTIGEN INTO THREE SEROLOGICAL TYPES, WITH SPECIAL REFERENCE TO THE BACTERICIDAL TEST

1957 • 288 citations

M proteins of group A streptococci

1974 • 128 citations

EPIDEMIOLOGIC CHARACTERIZATION OF GROUP A STREPTOCOCCI BY T-AGGLUTINATION AND M-PRECIPITATION TESTS IN THE PUBLIC HEALTH LABORATORY.

1965 • 125 citations

Restricted deposition of C3 on M+ group A streptococci: correlation with resistance to phagocytosis.

1982 • 96 citations

VARIANTS OF HEMOLYTIC STREPTOCOCCI; THEIR RELATION TO TYPE-SPECIFIC SUBSTANCE, VIRULENCE, AND TOXIN

1928 • 81 citations

Streptococcal M protein extracted by nonionic detergent. I. Properties of the antiphagocytic and type-specific molecules.

1976 • 80 citations

Expression of Streptococcal M Protein inEscherichia coli

1983 • 65 citations

VARIATION OCCURRING IN GROUP A STREPTOCOCCI DURING HUMAN INFECTION

1948 • 62 citations

Direct immunoassay for detecting Escherichia coli colonies that contain polypeptides encoded by cloned DNA segments.

1981 • 57 citations

Cosmid DNA packaging in vivo

1982 • 54 citations

Bacteriophage control of antiphagocytic determinants in group A streptococci.

1980 • 50 citations

Human neutrophil chemotactic response to group A streptococci: bacteria-mediated interference with complement-derived chemotactic factors

1983 • 49 citations

Genetic instability of M protein and serum opacity factor of group A streptocci: evidence suggesting extrachromosomal control

1975 • 36 citations

VARIATION IN THE M-ANTIGEN OF GROUP-A STREPTOCOCCI

1969 • 33 citations

A DNA substitution in the group A streptococcal bacteriophage SP24

1983 • 24 citations

Genetic Variation in the M Antigen of Group A Streptococci: Reassortment of Type-Specific Markers and Possible Antigenic Drift

1979 • 18 citations

Some observations on the influence of the micro-environment on loss of M substance in strains of Streptococcus pyogenes

1956 • 5 citations

Observations on the Virulence of Hæmolytic Streptococci

1927 • 4 citations