Activation of protein breakdown and prostaglandin E2 production in rat skeletal muscle in fever is signaled by a macrophage product distinct from interleukin 1 or other known monokines.

Shock and Tissue Injury Induced by Recombinant Human Cachectin

1986 • 2,587 citations

Tumor Necrosis Factor (TNF)

1985 • 1,932 citations

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

Interleukin-1

1984 • 1,625 citations

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

1985 • 1,594 citations

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

1986 • 1,501 citations

Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts.

1985 • 1,240 citations

Transforming Growth Factor-β: Biological Function and Chemical Structure

1986 • 1,198 citations

Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.

1984 • 1,042 citations

New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.

1981 • 925 citations

Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells.

1985 • 833 citations

Cloning and expression of murine interleukin-1 cDNA in Escherichia coli

1984 • 820 citations

A significant part of macrophage-derived growth factor consists of at least two forms of PDGF

1985 • 719 citations

Stimulation of Muscle Protein Degradation and Prostaglandin E₂Release by Leukocytic Pyrogen (Interleukin-1)

1983 • 689 citations

A Macrophage Factor Inhibits Adipocyte Gene Expression: An in Vitro Model of Cachexia

1985 • 525 citations

A review of infectious bovine rhinotracheitis, shipping fever pneumonia and viral-bacterial synergism in respiratory disease of cattle.

1982 • 485 citations

Muscle Proteolysis Induced by a Circulating Peptide in Patients with Sepsis or Trauma

1983 • 469 citations

Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle?

1982 • 445 citations

Alpha and beta human transforming growth factors stimulate prostaglandin production and bone resorption in cultured mouse calvaria.

1985 • 382 citations

The toxic effects of tumor necrosis factor in vivo and their prevention by cyclooxygenase inhibitors.

1987 • 295 citations

Weight loss associated with an endotoxin-induced mediator from peritoneal macrophages: The role of cachectin (tumor necrosis factor)

1985 • 205 citations

The effects of endotoxaemia on protein metabolism in skeletal muscle and liver of fed and fasted rats

1986 • 203 citations

Maintenance of normal length improves protein balance and energy status in isolated rat skeletal muscles

1986 • 189 citations

Stimulation of Bone Resorption in Vitro by Synthetic Transforming Growth Factor-Alpha

1985 • 154 citations

Purification and characterization of human interleukin‐1β expressed in recombinant Escherichia coli

1986 • 153 citations

Cleavage of human interleukin 1: isolation of a peptide fragment from plasma of febrile humans and activated monocytes.

1984 • 136 citations

High-molecular-weight transforming growth factor activity in the urine of patients with disseminated cancer.

1983 • 122 citations

Tumor necrosis factor can induce fever in rats without activating protein breakdown in muscle or lipolysis in adipose tissue.

1988 • 111 citations

Physiological Effects of Transforming Growth Factor in the Newborn Mouse

1985 • 107 citations

Inhibitors of prostaglandin synthesis or cathepsin B prevent muscle wasting due to sepsis in the rat.

1984 • 93 citations

Effect of ibuprofen on fever and metabolic changes induced by continuous infusion of leukocytic pyrogen (interleukin 1) or endotoxin

1983 • 86 citations

Transforming growth factors in the urine of normal, pregnant, and tumor-bearing humans.

1982 • 85 citations

Pneumonia in calves produced with aerosols of bovine herpesvirus 1 and Pasteurella haemolytica.

1978 • 82 citations

Control of protein degradation in muscle by prostaglandins, Ca2+, and leukocytic pyrogen (interleukin 1).

1984 • 78 citations

Characteristics of an Epidermal Cell Thymocyte-Activating Factor (ETAF) Produced by Human Epidermal Cells and a Human Squamous Cell Carcinoma Cell Line

1983 • 74 citations

Metabolic effects of infection

1986 • 71 citations

Leukocyte endogenous mediator alters protein dynamics in rats

1983 • 61 citations

Epidermal cytokines: properties of epidermal cell thymocyte-activating factor (ETAF).

1984 • 42 citations

Characterization of a factor from the U937 cell line that enhances the toxicity of human eosinophils to Schistosoma mansoni larvae.

1987 • 33 citations

The stimulations of arachidonic acid metabolism by recombinant murine interleukin 1 and tumor promoters or 1-oleoyl-2-acetyl-glycerol are synergistic.

1985 • 31 citations

Stimulation of muscle protein degradation and prostaglandin E2 release by leukocytic pyrogen (Interleukin-1)

1983 • 10 citations