Chronic methylphenidate alters locomotor activity and dopamine transporters differently from cocaine

Is Methylphenidate Like Cocaine?

1995 • 575 citations

Cocaine self-administration in dopamine-transporter knockout mice

1998 • 523 citations

Increasing effects of repetitive cocaine administration in the rat

1976 • 437 citations

Behavioral and neurochemical effects of acute and daily cocaine administration in rats.

1988 • 299 citations

Cocaine disposition in the brain after continuous or intermittent treatment and locomotor stimulation in mice.

1987 • 193 citations

Cocaine and 3.beta.-(4'-Substituted phenyl)tropane-2.beta.-carboxylic Acid Ester and Amide Analogs. New High-Affinity and Selective Compounds for the Dopamine Transporter

1995 • 185 citations

Repeated cocaine administration induces behavioral sensitization and corresponding decreased extracellular dopamine responses in caudate and accumbens

1992 • 181 citations

Comparison of the effects of cocaine and other inhibitors of dopamine uptake in rat striatum, nucleus accumbens, olfactory tubercle, and medial prefrontal cortex

1990 • 128 citations

Sensitization to locomotor effects of methylphenidate in the rat

1997 • 119 citations

Daily cocaine treatment produces a persistent reduction of [3H]dopamine uptake in vitro in rat nucleus accumbens but not in striatum

1990 • 108 citations

Inhibition of dopamine uptake by cocaine and nicotine: tolerance to chronic treatments

1992 • 82 citations

Dose response characteristics of methylphenidate on different indices of rats' locomotor activity at the beginning of the dark cycle

1996 • 78 citations

A comparison of the motor-activating effects of acute and chronic exposure to amphetamine and methylphenidate

1993 • 69 citations

Binding of bromine-substituted analogs of methylphenidate to monoamine transporters

1994 • 55 citations

Methylphenidate: diurnal effects on locomotor and stereotypic behavior in the rat

1997 • 53 citations

Alterations in locomotor activity during chronic cocaine administration: effect on dopamine receptors and interaction with opioids.

1998 • 44 citations

Continuous or intermittent cocaine administration: Effects of flupenthixol treatment during withdrawal

1994 • 39 citations

Continuous infusion of selective dopamine uptake inhibitors or cocaine produces time-dependent changes in rat locomotor activity

1999 • 38 citations

Behavioral and neurochemical effects of continuous infusion of cocaine in rats

1992 • 35 citations

Chronic administration of the selective dopamine uptake inhibitor GBR 12909, but not cocaine, produces marked decreases in dopamine transporter density

1997 • 33 citations

Can stimulant binding and dopamine transport be differentiated? Studies with GBR 12783 derivatives

1994 • 26 citations

Locomotor stereotypy is produced by methylphenidate and amfonelic acid and reduced by haloperidol but not clozapine or thioridazine

1993 • 25 citations