Chronic administration of the selective dopamine uptake inhibitor GBR 12909, but not cocaine, produces marked decreases in dopamine transporter density

Cloning and Expression of a Cocaine-Sensitive Rat Dopamine Transporter

1991 • 587 citations

Cloning and Expression of a Cocaine-Sensitive Dopamine Transporter Complementary DNA

1991 • 584 citations

The dopamine uptake inhibitor GBR 12909: selectivity and molecular mechanism of action

1989 • 343 citations

Behavioral properties of GBR 12909, GBR 13069 and GBR 13098: Specific inhibitors of dopamine uptake

1984 • 233 citations

Cocaine binding at σ receptors

1988 • 208 citations

Cocaine disposition in the brain after continuous or intermittent treatment and locomotor stimulation in mice.

1987 • 193 citations

A review of the effects of dopaminergic agents on humans, animals, and drug-seeking behavior, and its implications for medication development

1995 • 164 citations

Differences in Dopamine Clearance and Diffusion in Rat Striatum and Nucleus Accumbens Following Systemic Cocaine Administration

1992 • 152 citations

ChemInform Abstract: ARYL 1,4‐DIALK(EN)YLPIPERAZINES AS SELECTIVE AND VERY POTENT INHIBITORS OF DOPAMINE UPTAKE

1981 • 150 citations

Cocaine use increases [3HWIN 35428 binding sites in human striatum

1993 • 129 citations

Comparison of the effects of cocaine and other inhibitors of dopamine uptake in rat striatum, nucleus accumbens, olfactory tubercle, and medial prefrontal cortex

1990 • 128 citations

High-affinity [3H]GBR 12783 binding to a specific site associated with the neuronal dopamine uptake complex in the central nervous system

1986 • 110 citations

Intermittent and Continuous cocaine Administration: Residual Behavioral states during withdrawal

1992 • 108 citations

GBR12909 attenuates cocaine-induced activation of mesolimbic dopamine neurons in the rat.

1994 • 103 citations

Neurotransmitter Transporters: Molecular Biology, Function, and Regulation

1995 • 101 citations

Reduction in dopamine transporter mRNA after cessation of repeated cocaine administration

1994 • 94 citations

Dopamine uptake sites in the striatum are distributed differentially in striosome and matrix compartments.

1989 • 88 citations

Lack of increase in dopamine transporter binding or function in rat brain tissue after treatment with blockers of neuronal uptake of dopamine

1991 • 83 citations

Inhibition of dopamine uptake by cocaine and nicotine: tolerance to chronic treatments

1992 • 82 citations

Cocaine and GBR12909 produce equivalent motoric responses at different occupancy of the dopamine transporter

1992 • 81 citations

Differential reinforcing effects of cocaine and GBR-12909: biochemical evidence for divergent neuroadaptive changes in the mesolimbic dopaminergic system.

1996 • 79 citations

Dopamine transporters in the nucleus accumbens and the striatum have different apparent molecular weights

1991 • 79 citations

Evidence for mutually exclusive binding of cocaine, BTCP, GBR 12935, and dopamine to the dopamine transporter

1992 • 76 citations

[3H]cocaine binding and inhibition of [3H]dopamine uptake is similar in both the rat striatum and nucleus accumbens

1989 • 76 citations

Quantitation of Rat Dopamine Transporter mRNA: Effects of Cocaine Treatment and Withdrawal

1992 • 63 citations

Differential relationships among dopamine transporter affinities and stimulant potencies of various uptake inhibitors

1994 • 59 citations

Unaltered [3H]GBR-12935 binding after chronic treatment with dopamine active drugs

1990 • 57 citations

Dopamine transporter: deglycosylation with exo- and endoglycosidases

1991 • 48 citations

Expression of a single dopamine transporter cDNA can confer two cocaine binding sites

1992 • 44 citations

Evidence that pure uptake inhibitors including cocaine interact slowly with the dopamine neuronal carrier

1994 • 42 citations

Cocaine and GBR 12783 recognize nonidentical, overlapping binding domains on the dopamine neuronal carrier

1994 • 39 citations

Neuropeptide-dopamine interactions. V. Cyclo(His-Pro) regulation of striatal dopamine transporter complex

1990 • 35 citations

Isothiocyanate derivatives of cocaine: irreversible inhibition of ligand binding at the dopamine transporter.

1991 • 34 citations

GBR 12909 and 12935 block dopamine uptake into brain synaptic vesicles as well as nerve endings

1994 • 30 citations

Interaction of [3H]GBR 12935 and GBR 12909 with the dopamine uptake complex in nucleus accumbens

1990 • 29 citations

Dopaminergic modulation of serotonin metabolism in rat striatum: A study with dopamine uptake inhibitor GBR-12909

1995 • 20 citations

Characterization of binding of [3H]GBR 12935 (1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)-piperazine) to membranes and to solubilized membrane extracts from terminal field regions of mesolimbic, mesocortical and nigrostriatal dopamine pathways

1990 • 16 citations

The cocaine analog WIN 35,428 binds to two sites in fresh rat caudate-putamen: Significance of assay procedures

1993 • 16 citations

Increased μ-opioid efficacy for inhibition of adenylyl cyclase induced by chronic treatment with naltrexone or cocaine

1994 • 4 citations

Invariance of the density of dopamine uptake sites and dopamine metabolism in the rat brain after a chronic treatment with the dopamine uptake inhibitor GBR 12783

1994 • 3 citations