Miniglucagon (Glucagon 19–29), a Potent and Efficient Inhibitor of Secretagogue-induced Insulin Release through a Ca2+Pathway

Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen.

1992 • 688 citations

Post-Translational Proteolysis in Polypeptide Hormone Biosynthesis

1982 • 590 citations

PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues.

1991 • 589 citations

Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets

1993 • 430 citations

Kex2-like endoproteases PC2 and PC3 accurately cleave a model prohormone in mammalian cells: evidence for a common core of neuroendocrine processing enzymes.

1991 • 317 citations

The agonist effect of dihydropyridines on Ca channels

1984 • 264 citations

Neurotransmitter-Induced Inhibition of Exocytosis in Insulin-Secreting β Cells by Activation of Calcineurin

1996 • 180 citations

Mechanistic considerations in chemopreventive drug development

1994 • 176 citations

Proteases and posttranslational processing of prohormones: a review

1983 • 144 citations

Activation by adrenaline of a low-conductance G protein-dependent K+ channel in mouse pancreatic B cells

1991 • 133 citations

Somatostatin: Mechanism of Action in Pancreatic Islet β-Cells

1981 • 90 citations

A glucagon fragment is responsible for the inhibition of the liver Ca2+ pump by glucagon

1987 • 87 citations

Ca2+ agonists: new, sensitive probes for Ca2+ channels

1988 • 83 citations

Permeation and gating properties of the L-type calcium channel in mouse pancreatic beta cells.

1993 • 75 citations

Galanin and Epinephrine Act on Distinct Receptors to Inhibit Insulin Release by the Same Mechanisms Including an Increase in K⁺Permeability of the B-Cell Membrane*

1990 • 69 citations

Gating and blocking of calcium channels by dihydropyridines in the pancreatic B-CELL

1984 • 63 citations

Proteolytic events in the post-translational processing of polypeptide hormone precursors

1987 • 63 citations

Glucagon-(19-29), a Ca2+ pump inhibitory peptide, is processed from glucagon in the rat liver plasma membrane by a thiol endopeptidase.

1990 • 51 citations

Effect of Rise in cAMP Levels on Ca2+ Influx Through Voltage-Dependent Ca2+ Channels in HIT Cells: Second-Messenger Synarchy in β-Cells

1989 • 51 citations

G protein‐dependent inhibition of L‐type Ca2+ currents by acetylcholine in mouse pancreatic B‐cells.

1997 • 47 citations

Glucagon-(19-29) exerts a biphasic action on the liver plasma membrane Ca2+ pump which is mediated by G proteins.

1990 • 46 citations

Electrophysiological and Metabolic Characterization of Single β-Cells and Islets From Diabetic GK Rats

1998 • 45 citations

Islet Electrical Pacemaker Response to Alpha-Adrenergic Stimulation

1982 • 43 citations

Miniglucagon [glucagon-(19-29)] is a component of the positive inotropic effect of glucagon

1991 • 36 citations

Somatostatin inhibition of glucose-induced electrical activity in cultured rat islet cells

1977 • 25 citations

Endopeptidase from rat liver membranes, which generates miniglucagon from glucagon.

1993 • 23 citations

Preproglucagon and Its Processing

1996 • 10 citations

FACTORS AFFECTING THE SENSITIVITY OF AN IMMUNORADIOMETRIC ASSAY FOR ADRENOCORTICOTROPIC HORMONE

1992 • 7 citations

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