TNF-α mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity

[1] Role of free radicals and catalytic metal ions in human disease: An overview

1990 • 5,041 citations

Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases

1997 • 4,661 citations

Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response.

1996 • 1,167 citations

A Novel Proteolytic Cleavage Involved in Notch Signaling

2000 • 1,080 citations

Clinical development of platinum complexes in cancer therapy: an historical perspective and an update

1998 • 738 citations

Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity.

1995 • 599 citations

Overexpression of Manganese Superoxide Dismutase Suppresses Tumor Necrosis Factor-induced Apoptosis and Activation of Nuclear Transcription Factor-κB and Activated Protein-1

1998 • 580 citations

The cytokine-adhesion molecule cascade in ischemia/reperfusion injury of the rat kidney. Inhibition by a soluble P-selectin ligand.

1997 • 503 citations

Functional Analysis of the Domain Structure of Tumor Necrosis Factor-α Converting Enzyme

2000 • 496 citations

Antibody to intercellular adhesion molecule 1 protects the kidney against ischemic injury.

1994 • 495 citations

Mechanisms of death induced by cisplatin in proximal tubular epithelial cells: apoptosis vs. necrosis

1996 • 442 citations

Pentoxifylline efficacy in the treatment of intermittent claudication: Multicenter controlled double-blind trial with objective assessment of chronic occlusive arterial disease patients

1982 • 425 citations

Identification of the CD4+ T cell as a major pathogenic factor in ischemic acute renal failure

2001 • 419 citations

Interleukin-10 inhibits ischemic and cisplatin-induced acute renal injury

2001 • 389 citations

Identification of the CD4+ T cell as a major pathogenic factor in ischemic acute renal failure

2001 • 381 citations

Pathophysiological role of T lymphocytes in renal ischemia-reperfusion injury in mice

2000 • 344 citations

Tumor necrosis factor-α converting enzyme

2002 • 341 citations

Heme oxygenase-1 gene ablation or expression modulates cisplatin-induced renal tubular apoptosis

2000 • 316 citations

Nephrotoxicity Induced by Cancer Chemotherapy With Special Emphasis on Cisplatin Toxicity

1986 • 301 citations

In vitro and in vivo evidence suggesting a role for iron in cisplatin-induced nephrotoxicity

1998 • 296 citations

Early kidney TNF-α expression mediates neutrophil infiltration and injury after renal ischemia-reperfusion

1999 • 287 citations

The role of oxygen free radicals in cisplatin-induced acute renal failure in rats

1998 • 286 citations

Cell biology and molecular mechanisms of injury in ischemic acute renal failure

2000 • 283 citations

Manganese Superoxide Dismutase Attenuates Cisplatin-Induced Renal Injury

2001 • 265 citations

Induction of p21WAF1/CIP1/SDI1 in kidney tubule cells affects the course of cisplatin-induced acute renal failure.

1998 • 265 citations

Role and regulation of activation of caspases in cisplatin-induced injury to renal tubular epithelial cells

2001 • 265 citations

Induction of heme oxygenase in toxic renal injury: A protective role in cisplatin nephrotoxicity in the rat

1995 • 263 citations

Assessment of Cisplatin-Induced Nephrotoxicity by Microarray Technology

2001 • 224 citations

Endotoxemic renal failure in mice: Role of tumor necrosis factor independent of inducible nitric oxide synthase

2001 • 206 citations

Critical subcellular targets of cisplatin and related platinum analogs in rat renal proximal tubule cells

1995 • 152 citations

PROMINENT AND SUSTAINED UP-REGULATION OF GP130-SIGNALING CYTOKINES AND OF THE CHEMOKINE MIP-2 IN MURINE RENAL ISCHEMIA-REPERFUSION INJURY1

2000 • 150 citations

INVOLVEMENT OF ENDOGENOUS INTERLEUKIN-10 AND TUMOR NECROSIS FACTOR-?? IN RENAL ISCHEMIA-REPERFUSION INJURY1,2

1999 • 149 citations

Chemotactic factors and renal inflammation

1998 • 135 citations

Expression of apoptosis regulatory proteins in tubular epithelium stressed in culture or following acute renal failure

2000 • 133 citations

Adverse effects of anti-tumor drug, cisplatin, on rat kidney mitochondria: Disturbances in glutathione peroxidase activity

1989 • 129 citations

Protection from toxicant-mediated renal injury in the rat with anti-CD54 antibody

1999 • 111 citations

Chemokine and Chemokine Receptor Expression in a Novel Human Mesangial Cell Line

1999 • 110 citations

Differential regulation of TNFα, IL-1β, IL-6, IL-8, TNFβ, and IL-10 by pentoxifylline

1996 • 107 citations

Tissue remodeling during tumor necrosis factor-induced apoptosis in LLC-PK1 renal epithelial cells

1996 • 104 citations

Effect of neutrophil depletion on ischemic renal injury in the rat.

1989 • 102 citations

The roles of caspase-3 and bcl-2 in chemically-induced apoptosis but not necrosis of renal epithelial cells

1999 • 78 citations

Role of apoptosis in cisplatin-induced toxicity in the renal epithelial cell line LLC-PK1

2000 • 75 citations

IL-1 and TNF independent pathways mediate ICAM-1/VCAM-1 up-regulation in ischemia reperfusion injury

2001 • 72 citations

Overexpression of Catalase in the Mitochondrial or Cytosolic Compartment Increases Sensitivity of HepG2 Cells to Tumor Necrosis Factor-α-induced Apoptosis

2000 • 65 citations

Role of Angiotensin II, Endothelin-1, and Nitric Oxide in HgCl2-Induced Acute Renal Failure

1998 • 43 citations

Antibodies to both ICAM-1 and LFA-1 do not protect the kidney against toxic (HgCl2) injury

2000 • 22 citations

α-Melanocyte-simulating hormone and interleukin-10 do not protect the kidney against mercuric chloride-induced injury

2002 • 19 citations

Modulation of Tumor Necrosis Factor by Reactive Oxygen Metabolites

1992 • 4 citations