Liposomal Vaccines: Clinical Status and Immunological Presentation for Humoral and Cellular Immunity

Introduction of soluble protein into the class I pathway of antigen processing and presentation

1988 • 1,105 citations

Liposomes as drug carriers

1977 • 664 citations

Identity of the 19S 'prosome' particle with the large multifunctional protease complex of mammalian cells (the proteasome)

1988 • 404 citations

Liposomes as carriers of antigens and adjuvants

1991 • 350 citations

The Cell Biology of Antigen Processing and Presentation

1991 • 349 citations

A Vital Stain for the Golgi Apparatus

1985 • 344 citations

Liposomal malaria vaccine in humans: a safe and potent adjuvant strategy.

1992 • 231 citations

Liposome-encapsulated antigens engender lysosomal processing for class II MHC presentation and cytosolic processing for class I presentation.

1991 • 164 citations

Immunopotentiating reconstituted influenza virus virosome vaccine delivery system for immunization against hepatitis A.

1992 • 158 citations

Lipopolysaccharide, lipid A, and liposomes containing lipid A as immunologic adjuvants

1993 • 150 citations

Macrophages as accessory cells for class I MHC-restricted immune responses.

1991 • 148 citations

In vivo cytotoxic T lymphocyte induction with soluble proteins administered in liposomes.

1992 • 133 citations

Cellular Interactions in the Humoral Immune Response

1989 • 121 citations

Processing of exogenous liposome-encapsulated antigens in vivo generates class I MHC-restricted T cell responses.

1992 • 117 citations

pH sensitive liposomes provide an efficient means of sensitizing target cells to class I restricted CTL recognition of a soluble protein

1991 • 114 citations

Lipid traffic in eukaryotic cells: mechanisms for intracelluar transport and organelle-specific enrichment of lipids

1990 • 114 citations

Immunologic aspects of liposomes: presentation and processing of liposomal protein and phospholipid antigens

1992 • 109 citations

Antiviral Cytotoxic T Lymphocyte Induction and Vaccination

1988 • 98 citations

Cationic lipids direct a viral glycoprotein into the class I major histocompatibility complex antigen-presentation pathway.

1992 • 90 citations

Induction of primary, antiviral cytotoxic, and proliferative responses with antigens administered via dendritic cells

1993 • 86 citations

Effect of liposome encapsulation on antigen presentation in vitro. Comparison of presentation by peritoneal macrophages and B cell tumors.

1989 • 85 citations

Antigen presentation ¹

1989 • 78 citations

Adjuvant effects of liposomes containing lipid A: enhancement of liposomal antigen presentation and recruitment of macrophages

1992 • 74 citations

Vaccination of rhesus monkeys with synthetic peptide in a fusogenic proteoliposome elicits simian immunodeficiency virus-specific CD8+ cytotoxic T lymphocytes.

1992 • 71 citations

The role of macrophages in the immunoadjuvant action of liposomes: effects of elimination of splenic macrophages on the immune response against intravenously injected liposome-associated albumin antigen.

1989 • 69 citations

Development of a new type of influenza subunit vaccine made by muramyldipeptide-liposome: enhancement of humoral and cellular immune responses

1990 • 63 citations

Phagocytosis of liposomes by macrophages: intracellular fate of liposomal malaria antigen

1991 • 63 citations

A rational design of synthetic peptide vaccine with a built‐in adjuvant

1992 • 63 citations

The role of macrophages in promoting the antibody response mediated by liposome-associated protein antigens

1982 • 62 citations

A single vaccination with an inactivated hepatitis A liposome vaccine induces protective antibodies after only two weeks

1992 • 59 citations

Immunopotentiating reconstituted influenza virosomes (IRIVs) and other adjuvants for improved presentation of small antigens

1992 • 53 citations

Liposome‐mediated delivery stimulates a class I‐restricted cytotoxic T cell response to soluble antigen

1992 • 53 citations

ATP-dependent fusion of liposomes with the Golgi apparatus of perforated cells

1988 • 50 citations

The Golgi apparatus: insights from lipid biochemistry

1990 • 48 citations

Electroporation and commercial liposomes efficiently deliver soluble protein into the MHC class I presentation pathway

1993 • 46 citations

Macrophages as accessory cells in the in vivo humoral immune response: from processing of particulate antigens to regulation by suppression.

1992 • 40 citations

Antigen presentation at the inflammatory site.

1989 • 40 citations

Induction of cytolytic and antibody responses using Plasmodium falciparum repeatless circumsporozoite protein encapsulated in liposomes

1993 • 40 citations

Intramuscular absorption and regional lymphatic uptake of liposome-entrapped inulin.

1981 • 37 citations

Liposomes in Immunology: The Immune Response Against Antigen-Containing Liposomes

1977 • 36 citations

Phase 1 clinical tests of influenza MDP-virosome vaccine (KD-5382)

1992 • 34 citations

An improved method of loading pH-sensitive liposomes with soluble proteins for class I restricted antigen presentation

1991 • 33 citations

Novel Adjuvant Strategies for Experimental Malaria and AIDS Vaccines

1993 • 32 citations

Postimmunization Clearance of Liposome Entrapped Adenovirus Type 5 Hexon

1982 • 29 citations

In vitro fusion of rabbit liver Golgi membranes with liposomes.

1993 • 24 citations

Liposome facilitated xenogeneic approach for studying human colon cancer immunity: carrier and adjuvant effect of liposomes.

1984 • 23 citations

In vitro induction of primary and secondary xenoimmune responses by liposomes containing human colon tumor cell antigens

1982 • 22 citations

Presentation of an MuLV-related tumour antigen in liposomes as a potent tertiary immunogen after adoptive transfer.

1986 • 18 citations

Design of a Complete Synthetic Peptide-Based AIDS Vaccine with a Built-in Adjuvant

1992 • 18 citations

H-2 antigens incorporated into phospholipid vesicles elicit specific allogeneic cytotoxic T lymphocytes

1980 • 18 citations

A study of the inability of subcellular fractions to elicit primary anti-H-2 cytotoxic T lymphocytes

1981 • 9 citations

Liposomes as Safe Carriers of Drugs and Vaccines

1992 • 3 citations