Differential expression of renal AGE-receptor genes in NOD mice: Possible role in nonobese diabetic renal disease

Advanced Glycosylation End Products in Patients with Diabetic Nephropathy

1991 • 925 citations

Pathogenic effects of advanced glycosylation: biochemical, biologic, and clinical implications for diabetes and aging.

1994 • 863 citations

Expression of galectin-3 modulates T-cell growth and apoptosis.

1996 • 771 citations

Cellular receptors for advanced glycation end products. Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis of vascular lesions.

1994 • 632 citations

Cachectin/TNF and IL-1 Induced by Glucose-Modified Proteins: Role in Normal Tissue Remodeling

1988 • 606 citations

Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis.

1998 • 505 citations

Immunochemical detection of advanced glycosylation end products in vivo.

1992 • 496 citations

Identification of Galectin-3 As a High-Affinity Binding Protein for Advanced Glycation End Products (AGE): A New Member of the AGE-Receptor Complex

1995 • 410 citations

Reactive glycosylation endproducts in diabetic uraemia and treatment of renal failure

1994 • 374 citations

Advanced protein glycosylation induces transendothelial human monocyte chemotaxis and secretion of platelet-derived growth factor: role in vascular disease of diabetes and aging.

1990 • 370 citations

Receptor-specific increase in extracellular matrix production in mouse mesangial cells by advanced glycosylation end products is mediated via platelet-derived growth factor.

1992 • 353 citations

Molecular identity and cellular distribution of advanced glycation endproduct receptors: relationship of p60 to OST-48 and p90 to 80K-H membrane proteins.

1996 • 340 citations

Receptor for advanced glycation end products (AGEs) has a central role in vessel wall interactions and gene activation in response to circulating AGE proteins.

1994 • 318 citations

High-affinity-receptor-mediated uptake and degradation of glucose-modified proteins: a potential mechanism for the removal of senescent macromolecules.

1985 • 312 citations

Advanced glycation end products up-regulate gene expression found in diabetic glomerular disease.

1994 • 298 citations

Receptor-specific induction of insulin-like growth factor I in human monocytes by advanced glycosylation end product-modified proteins.

1992 • 261 citations

Biochemistry, molecular biology, and genetics of the oligosaccharyltransferase

1996 • 253 citations

Human and rat mesangial cell receptors for glucose-modified proteins: potential role in kidney tissue remodelling and diabetic nephropathy.

1991 • 243 citations

Macrophages adhere to glucose-modified basement membrane collagen IV via their scavenger receptors.

1994 • 182 citations

Prevention of cardiovascular and renal pathology of aging by the advanced glycation inhibitor aminoguanidine.

1996 • 180 citations

Evidence for the central role of glomerular growth promoters in the development of sclerosis.

1989 • 154 citations

Renoprotection in diabetes: genetic and non-genetic risk factors and treatment

1998 • 143 citations

Upregulation of Mesangial Growth Factor and Extracellular Matrix Synthesis by Advanced Glycation End Products Via a Receptor-Mediated Mechanism

1997 • 129 citations

Characterization of the Advanced Glycation End-Product Receptor Complex in Human Vascular Endothelial Cells

1999 • 107 citations

The Receptor for Advanced Glycation End Products Mediates the Chemotaxis of Rabbit Smooth Muscle Cells

1997 • 98 citations

Galectin-3 modulates rat mesangial cell proliferation and matrix synthesis during experimental glomerulonephritis induced by anti-Thy1.1 antibodies

1999 • 84 citations

Overexpression of transforming growth factor-beta 1 mRNA is associated with up-regulation of glomerular tenascin and laminin gene expression in nonobese diabetic mice.

1995 • 82 citations

Macrophage/monocyte receptor for nonenzymatically glycosylated protein is upregulated by cachectin/tumor necrosis factor.

1989 • 69 citations

Specific Macrophage Receptor Activity for Advanced Glycosylation End Products Inversely Correlates With Insulin Levels In Vivo

1988 • 68 citations

Identification of p90, a Prominent Tyrosine-phosphorylated Protein in Fibroblast Growth Factor-stimulated Cells, as 80K-H

1996 • 67 citations

Glomerular lesions in nonobese diabetic mouse: before and after the onset of hyperglycemia.

1990 • 62 citations

Receptors for Advanced Glycosylation Endproducts in Human Brain: Role in Brain Homeostasis

1998 • 59 citations

Purification of two distinct proteins of approximate Mr 80,000 from human epithelial cells and identification as proper substrates for protein kinase C

1990 • 56 citations

Genetic susceptibility to nephropathy in insulin‐dependent diabetes: From epidemiology to molecular genetics

1995 • 50 citations

Mesangial cells from diabetic NOD mice constitutively secrete increased amounts of insulin-like growth factor-I.

1993 • 39 citations

The genetics of the NOD mouse

1995 • 24 citations