Comparative studies of epibatidine derivatives [18F]NFEP and [18F]N-Methyl-NFEP: kinetics, nicotine effect, and toxicity

Graphical Analysis of Reversible Radioligand Binding from Time—Activity Measurements Applied to [N-¹¹C-Methyl]-(−)-Cocaine PET Studies in Human Subjects

1990 • 1,412 citations

Acetylcholine receptors containing the β2 subunit are involved in the reinforcing properties of nicotine

1998 • 1,304 citations

Effects of acute subcutaneous nicotine on attention, information processing and short-term memory in alzheimer's disease

1992 • 478 citations

Neuronal Nicotinic Acetylcholine Receptors as Targets for Drug Discovery

1997 • 440 citations

Neuronal Nicotinic Acetylcholine Receptors

1996 • 377 citations

Epibatidine, a potent analgetic and nicotinic agonist.

1994 • 371 citations

Broad-Spectrum, Non-Opioid Analgesic Activity by Selective Modulation of Neuronal Nicotinic Acetylcholine Receptors

1998 • 365 citations

Time course study of the effects of chronic nicotine infusion on drug response and brain receptors.

1985 • 271 citations

GABAergic inhibition of endogenous dopamine release measured in vivo with 11C-raclopride and positron emission tomography

1992 • 211 citations

Downregulation of nicotinic receptor function after chronic nicotine infusion.

1993 • 181 citations

(+/-)-Epibatidine elicits a diversity of in vitro and in vivo effects mediated by nicotinic acetylcholine receptors.

1994 • 166 citations

Methyllycaconitine and (+)‐anatoxin‐a differentiate between nicotinic receptors in vertebrate and invertebrate nervous systems

1988 • 151 citations

Nicotinic receptors in the brain

1996 • 120 citations

Mapping muscarinic receptors in human and baboon brain using [N‐¹¹C‐methyl]‐benztropine

1990 • 113 citations

High affinity binding of [3H] (−)-nicotine to rat brain membranes and its inhibition by analogues of nicotine

1988 • 103 citations

Pharmacological effects of epibatidine optical enantiomers

1994 • 94 citations

Mapping nicotinic acetylcholine receptors with PET

1996 • 71 citations

Synthesis of a radiotracer for studying nicotinic acetylcholine receptors: (+/−)-exo-2-(2-[18F]fluoro-5-pyridyl)-7-azabicyclo[2.2.1]heptane

1996 • 68 citations

Uptake and regional distribution of (+)-(R)- and (−)-(S)-N-[methyl-11C]-nicotine in the brains of Rhesus monkey an attempt to study nicotinic receptors in vivo

1989 • 67 citations

Fluoro-norchloroepibatidine: Preclinical assessment of acute toxicity

1997 • 61 citations

Carbon-11-d-threo-methylphenidate binding to dopamine transporter in baboon brain.

1995 • 61 citations

Antinociceptive effects of the alkaloid epibatidine: Further studies on involvement of nicotinic receptors

1995 • 53 citations

Epibatidine, an alkaloid from the poison frog Epipedobates tricolor, is a powerful ganglionic depolarizing agent.

1994 • 51 citations

In vivo specific binding of [3H]-1-nicotine in the mouse brain

1989 • 47 citations

Synthesis of [18F]norchlorofluoroepibatidine and its N-methyl derivative: new PET ligands for mapping nicotinic acetylcholine receptors

1997 • 34 citations

Characterization of [3H]ABT-418: a novel cholinergic channel ligand.

1995 • 31 citations

In Vitro and Ex Vivo Autoradiographic Studies of Nicotinic Acetylcholine Receptors Using [18F]Fluoronorchloroepibatidine in Rodent and Human Brain

1998 • 27 citations

Histaminergic contribution to the metabolic effects of neuroglucopenia

1997 • 6 citations