High affinity binding of [3H] (−)-nicotine to rat brain membranes and its inhibition by analogues of nicotine

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

Central cholinergic pathways in the rat: An overview based on an alternative nomenclature (Ch1–Ch6)

1983 • 2,305 citations

Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-alpha-bungarotoxin

1985 • 1,037 citations

Quantitative analysis of drug-receptor interactions: I. Determination of kinetic and equilibrium properties

1981 • 557 citations

Chemistry and Pharmacology of Polypeptide Toxins in Snake Venoms

1972 • 479 citations

Stereospecific Nicotine Receptors on Rat Brain Membranes

1980 • 319 citations

Characterization of nicotine binding in mouse brain and comparison with the binding of alpha-bungarotoxin and quinuclidinyl benzilate.

1982 • 305 citations

Nicotinic binding sites in rat and mouse brain: comparison of acetylcholine, nicotine, and alpha-bungarotoxin.

1986 • 262 citations

Nicotinic cholinergic receptors labeled by [3H]acetylcholine in rat brain.

1982 • 259 citations

Autoradiographic distribution of nicotine receptors in rat brain

1984 • 253 citations

Regulation of dopamine release by presynaptic nicotinic receptors in rat striatal slices: Effect of nicotine in a low concentration

1979 • 250 citations

Origin and modulation of acetylcholine activity in the neostriatum

1974 • 174 citations

The nicotinic acetylcholine receptor and its ion channel

1986 • 169 citations

Role of training dose in discrimination of nicotine and related compounds by rats

1984 • 162 citations

The binding of L-[3H]nicotine to a single class of high affinity sites in rat brain membranes.

1986 • 122 citations

Characterization of the receptor mediating the nicotine discriminative stimulus

1981 • 112 citations

[3H]acetylcholine and [3H](-)nicotine label the same recognition site in rat brain.

1987 • 112 citations

Brain Nicotine Binding Sites

1987 • 93 citations

Nicotine injections as the conditioned stimulus in discrimination learning

1969 • 85 citations

α‐Bungarotoxin Binds to Low‐Affinity Nicotine Binding Sites in Rat Brain

1986 • 83 citations

Discriminative stimulus properties of the optical isomers of nicotine

1980 • 72 citations

Neosurugatoxin, a Specific Antagonist of Nicotinic Acetylcholine Receptors

1984 • 66 citations

Isoarecolone can inhibit nicotine binding and produce nicotine-like discriminative stimulus effects in rats

1987 • 54 citations

Binding of optically pure (−)‐[³H]nicotine to rat brain membranes

1983 • 47 citations

Nature of nicotine binding to rat brain P2 fraction

1984 • 47 citations

Neosurugatoxin blocks nicotinic acetylcholine receptors in the brain

1985 • 46 citations

Ganglionic nAChRs and high‐affinity nicotinic binding sites are not equivalent

1986 • 29 citations

Characterization of putative nicotinic acetylcholine receptors solubilized from rat brains

1986 • 28 citations

Binding characteristics of (−)- and (+)-nicotine to the rat brain P2 fraction

1985 • 22 citations

Inhibition by neurosurugatoxin of nicotine-induced antinociception

1986 • 17 citations

Antagonism of ganglionic stimulants by alpha, alpha'-bis-(dimethylammoniumacetaldehyde diethylacetal)-p,p'-diacetylbiphenyl bromide (DMAE).

1968 • 13 citations

Nicotinic receptors in mammalian brain

1984 • 13 citations

Effects of alpha,alpha'-bis-(dimethylammoniumacetaldehyde diethylacetal)-p,p'-diacetylbiphenyl bromide (DMAE) on neuromuscular transmission.

1969 • 8 citations

Ganglion-Blocking Drugs

1967 • 7 citations

Interactions of antinicotinic acetylcholine receptor antibodies with rat brain and muscle antigenic determinants

1986 • 6 citations

Stereospecificity of nicotine binding to rat brain

1986 • 3 citations