Morphants: a new systematic vertebrate functional genomics approach

Effective targeted gene ‘knockdown’ in zebrafish

2000 • 2,464 citations

The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio

1996 • 1,633 citations

Molecular Reconstruction of Sleeping Beauty, a Tc1-like Transposon from Fish, and Its Transposition in Human Cells

1997 • 1,383 citations

A genetic screen for mutations affecting embryogenesis in zebrafish.

1996 • 1,317 citations

Use of dsRNA-Mediated Genetic Interference to Demonstrate that frizzled and frizzled 2 Act in the Wingless Pathway

1998 • 1,116 citations

Morpholino Antisense Oligomers: Design, Preparation, and Properties

1997 • 1,052 citations

Specific interference with gene function by double-stranded RNA in early mouse development

1999 • 719 citations

Morpholino antisense oligomers: the case for an RNase H-independent structural type

1999 • 635 citations

βCatenin Signaling Activity Dissected in the Early Xenopus Embryo: A Novel Antisense Approach

2000 • 523 citations

A large-scale insertional mutagenesis screen in zebrafish

1999 • 489 citations

Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes

2000 • 435 citations

Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference

2000 • 412 citations

A Genetic Linkage Map for Zebrafish: Comparative Analysis and Localization of Genes and Expressed Sequences

1999 • 209 citations

Double–Stranded RNA Induces Specific Developmental Defects in Zebrafish Embryos

1999 • 205 citations

Too Much Interference: Injection of Double-Stranded RNA Has Nonspecific Effects in the Zebrafish Embryo

2000 • 158 citations

Double-Stranded RNA Injection Produces Null Phenotypes in Zebrafish

2000 • 155 citations

Morphants: a new systematic vertebrate functional genomics approach

2000 • 153 citations

Molecular Mechanisms of Holoprosencephaly

1999 • 141 citations

Transposition of the nematode Caenorhabditis elegans Tc3 element in the zebrafish Danio rerio

1998 • 133 citations

Zebrafishstat3 is expressed in restricted tissues during embryogenesis andstat1 rescues cytokine signaling in aSTAT1-deficient human cell line

1999 • 120 citations

Chapter 8 The Zebrafish Genome

1998 • 116 citations

Zebrafish mutations and functional analysis of the vertebrate genome.

2000 • 89 citations

Inactivation of the zebrafish homologue of Chx10 by antisense oligonucleotides causes eye malformations similar to the ocular retardation phenotype

1997 • 72 citations

c-Myc antisense limits rat liver regeneration and indicates role for c-Myc in regulating cytochrome P-450 3A activity.

2000 • 67 citations

Zebrafish mutations and functional analysis of the vertebrate genome: Table 1.

2000 • 65 citations

Gene silencing: Shrinking the black box of RNAi

2000 • 53 citations

In VivoEvaluation of a Morpholino Antisense Oligomer Directed Against Tumor Necrosis Factor-α

2000 • 37 citations