2.0 Å resolution structure of a ternary complex of pig muscle phosphoglycerate kinase containing 3-phospho-D-glycerate and the nucleotide Mn adenylylimidodiphosphate

Structure at 2.8 Â resolution of F1-ATPase from bovine heart mitochondria

1994 • 2,954 citations

Sparse matrix sampling: a screening method for crystallization of proteins

1991 • 2,050 citations

Crystallographic R Factor Refinement by Molecular Dynamics

1987 • 1,982 citations

A graphics model building and refinement system for macromolecules

1978 • 1,858 citations

Enzyme-Catalyzed Phosphoryl Transfer Reactions

1980 • 1,120 citations

Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis.

1990 • 1,077 citations

The α-helix dipole and the properties of proteins

1978 • 985 citations

Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis

1994 • 823 citations

Structural Mechanisms for Domain Movements in Proteins

1994 • 741 citations

Crystal structure of active elongation factor Tu reveals major domain rearrangements

1993 • 533 citations

Adenylyl imidiodiphosphate, an adenosine triphosphate analog containing a P-N-P linkage

1971 • 516 citations

Sequence, structure and activity of phosphoglycerate kinase: a possible hinge-bending enzyme

1979 • 452 citations

Phosphotransferase and substrate binding mechanism of the cAMP-dependent protein kinase catalytic subunit from porcine heart as deduced from the 2.0 A structure of the complex with Mn2+ adenylyl imidodiphosphate and inhibitor peptide PKI(5-24).

1993 • 399 citations

The crystal structure of elongation factor EF-Tu from Thermus aquaticus in the GTP conformation

1993 • 399 citations

Sequence and structure of yeast phosphoglycerate kinase.

1982 • 364 citations

2.2 Å refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor

1993 • 356 citations

Structural domains in proteins and their role in the dynamics of protein function

1983 • 283 citations

Structural and Functional Aspects of Domain Motions in Proteins

1984 • 246 citations

Structure of Yeast Phosphoglycerate Kinase

1974 • 222 citations

Structure of horse muscle phosphoglycerate kinase

1974 • 189 citations

How flexible is the furanose ring? 1. A comparison of experimental and theoretical studies

1982 • 183 citations

Substrate binding closes the cleft between the domains of yeast phosphoglycerate kinase.

1979 • 173 citations

Mechanisms of domain closure in proteins

1984 • 158 citations

High‐resolution structures of adenylate kinase from yeast ligated with inhibitor Ap₅A, showing the pathway of phosphoryl transfer

1995 • 144 citations

The closed conformation of a highly flexible protein: The structure of E. coli adenylate kinase with bound AMP and AMPPNP

1994 • 141 citations

A Structural Analysis of Phosphate and Sulphate Binding Sites in Proteins

1994 • 139 citations

The effect of divalent metal ions on the rate and transition-state structure of phosphoryl-transfer reactions

1987 • 133 citations

Crystal structure of the binary complex of pig muscle phosphoglycerate kinase and its substrate 3‐phospho‐<scp>D</scp>‐glycerate

1992 • 106 citations

Catalysis of the hydrolysis of phosphorylated pyridines by Mg(OH)+: a possible model for enzymic phosphoryl transfer

1990 • 94 citations

Phosphoglycerate kinase

1981 • 90 citations

The Structure of Uridylate Kinase with Its Substrates, Showing the Transition State Geometry

1994 • 79 citations

Analysis of chiral inorganic [16O, 17O, 18O]thiophosphate and the stereochemistry of the 3-phosphoglycerate kinase reaction.

1980 • 75 citations

Structure of the ADP complex of the 3-phosphoglycerate kinase from Bacillus stearothermophilus at 1.65 Å

1994 • 70 citations

Evolutionary conservation of the substrate‐binding cleft of phosphoglycerate kinases

1986 • 60 citations

Computer retrieval and analysis of molecular geometry. III. Geometry of the β-1'-aminofuranoside fragment

1978 • 60 citations

Nucleotide sequence of the phosphoglycerate kinase gene from the extreme thermophile Thermus thermophilus. Comparison of the deduced amino acid sequence with that of the mesophilic yeast phosphoglycerate kinase

1988 • 55 citations

Correlation between enzyme activity and hinge‐bending domain displacement in 3‐phosphoglycerate kinase

1989 • 51 citations

Conformations and arrangement of subtrates at active sites of ATP - utilizing enzymes

1981 • 31 citations

The Phosphoglycerate Kinase Reaction and its Metal Ion Specificity

1970 • 29 citations

Mg2+ affects the binding of ADP but not ATP to 3-phosphoglycerate kinase. Correlation between equilibrium dialysis binding and enzyme kinetic data

1993 • 27 citations

Probing the role of arginines and histidines in the catalytic function and activation of yeast 3-phosphoglycerate kinase by site-directed mutagenesis.

1990 • 20 citations

Inactivation of pig muscle 3-phosphoglycerate kinase by thiol modification depends on reagent size

1984 • 19 citations

Tryptophan phosphorescence as a monitor of the solution structure of phosphoglycerate kinase from yeast

1993 • 18 citations

Antagonistic binding of substrates to 3-phosphoglycerate kinase monitored by the fluorescent analogue 2′(3′)-O-(2,4,6-trinitrophenyl)adenosine 5′-triphosphate

1994 • 16 citations

Preliminary X-ray investigation of enzyme substrate complexes of horse muscle phosphoglycerate kinase

1984 • 16 citations

Characterization of the structure and properties of the His 62 → Ala and Arg 38 → Ala mutants of yeast phosphoglycerate kinase: An investigation of the catalytic and activatory sites by site‐directed mutagenesis and NMR

1992 • 15 citations

The effects of ligands on the conformation of phosphoglycerate kinase: Fluorescence anisotropy decay and theoretical interpretation

1990 • 12 citations

Substrate Activity of Rh(III)ATP with Phosphoglycerate Kinase and the Role of the Metal Ton in Catalysis

1994 • 10 citations