Loss of STAT1 expression confers resistance to IFN‐γ‐induced apoptosis in ME180 cells

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

1993 • 1,387 citations

Activation of the STAT Signaling Pathway Can Cause Expression of Caspase 1 and Apoptosis

1997 • 525 citations

Defective TNF-α-Induced Apoptosis in STAT1-Null Cells Due to Low Constitutive Levels of Caspases

1997 • 508 citations

Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1

1994 • 490 citations

Contribution of STAT SH2 Groups to Specific Interferon Signaling by the Jak-STAT pathway

1995 • 428 citations

DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity

1997 • 408 citations

DAP kinase links the control of apoptosis to metastasis

1997 • 394 citations

An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes

1997 • 364 citations

Cleavage of Focal Adhesion Kinase by Caspases during Apoptosis

1997 • 338 citations

Cooperation of the tumour suppressors IRF-1 and p53 in response to DNA damage

1996 • 326 citations

Interferon-γ Modulates a p53-independent Apoptotic Pathway and Apoptosis-related Gene Expression

1997 • 276 citations

Interferons up-regulate STAT1, STAT2, and IRF family transcription factor gene expression in human peripheral blood mononuclear cells and macrophages.

1997 • 211 citations

Formation of STAT1-STAT2 Heterodimers and Their Role in the Activation of IRF-1 Gene Transcription by Interferon-α

1996 • 196 citations

Dexamethasone inhibits lung epithelial cell apoptosis induced by IFN-γ and Fas

1997 • 148 citations

Fas/APO-1 gene transfer for human malignant glioma.

1995 • 127 citations

Regulation of the interferon system and cell growth by the IRF transcription factors

1995 • 115 citations

Interferon-γ InducesIceGene Expression and Enhances Cellular Susceptibility to Apoptosis in the U937 Leukemia Cell Line

1996 • 110 citations

Inhibition of tumor cell growth by interferon-gamma is mediated by two distinct mechanisms dependent upon oxygen tension: induction of tryptophan degradation and depletion of intracellular nicotinamide adenine dinucleotide.

1989 • 107 citations

CD95 (FAS/APO-1) Antibody-Mediated Apoptosis of Human Retinal Pigment Epithelial Cells

1995 • 33 citations

Treatment of ME180 Cells with Interferon-γ Causes Apoptosis as a Result of Tryptophan Starvation

1996 • 18 citations