TOR Regulates Ribosomal Protein Gene Expression via PKA and the Forkhead Transcription Factor FHL1

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

1998 • 5,253 citations

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

2002 • 3,624 citations

A comprehensive two-hybrid analysis to explore the yeast protein interactome

2001 • 3,564 citations

Getting started with yeast

2002 • 3,496 citations

Transcriptional Regulatory Networks in Saccharomyces cerevisiae

2002 • 2,967 citations

mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery

2002 • 2,904 citations

Genomic Libraries and a Host Strain Designed for Highly Efficient Two-Hybrid Selection in Yeast

1996 • 2,631 citations

[1] Getting started with yeast

1991 • 2,456 citations

TOR, a Central Controller of Cell Growth

2000 • 1,919 citations

The economics of ribosome biosynthesis in yeast

1999 • 1,869 citations

Two TOR Complexes, Only One of which Is Rapamycin Sensitive, Have Distinct Roles in Cell Growth Control

2002 • 1,831 citations

Sequencing and comparison of yeast species to identify genes and regulatory elements

2003 • 1,785 citations

Raptor, a Binding Partner of Target of Rapamycin (TOR), Mediates TOR Action

2002 • 1,758 citations

Regulation of translation initiation by FRAP/mTOR

2001 • 1,532 citations

A rapid and simple method for preparation of RNA fromSaccharomyces cerevisiae

1990 • 1,340 citations

The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors

1999 • 918 citations

Finding Functional Features in Saccharomyces Genomes by Phylogenetic Footprinting

2003 • 828 citations

A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size

2004 • 618 citations

Computational discovery of gene modules and regulatory networks

2003 • 615 citations

TOR signalling in bugs, brain and brawn

2003 • 568 citations

Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins

1999 • 526 citations

Spreading of transcriptional represser SIR3 from telomeric heterochromatin

1996 • 523 citations

mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability

2004 • 471 citations

The FHA domain

2001 • 423 citations

Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression

2004 • 388 citations

Regulation of Ribosome Biogenesis by the Rapamycin-sensitive TOR-signaling Pathway inSaccharomyces cerevisiae

1999 • 378 citations

Starvation Induces Vacuolar Targeting and Degradation of the Tryptophan Permease in Yeast

1999 • 289 citations

Coordinate Regulation of Yeast Ribosomal Protein Genes Is Associated with Targeted Recruitment of Esa1 Histone Acetylase

2000 • 286 citations

Activation of the RAS/Cyclic AMP Pathway Suppresses a TOR Deficiency in Yeast

2003 • 259 citations

Partitioning the transcriptional program induced by rapamycin among the effectors of the Tor proteins

2000 • 236 citations

Rapamycin Induces the G₀ Program of Transcriptional Repression in Yeast by Interfering with the TOR Signaling Pathway

1998 • 214 citations

Forkhead-like transcription factors recruit Ndd1 to the chromatin of G2/M-specific promoters

2000 • 201 citations

Loss of Ras activity in Saccharomyces cerevisiae is suppressed by disruptions of a new kinase gene, YAKI, whose product may act downstream of the cAMP-dependent protein kinase.

1989 • 199 citations

Chromatin-mediated regulation of nucleolar structure and RNA Pol I localization by TOR

2003 • 172 citations

Tor Pathway Regulates Rrn3p-dependent Recruitment of Yeast RNA Polymerase I to the Promoter but Does Not Participate in Alteration of the Number of Active Genes

2003 • 172 citations

The recruitment of RNA polymerase I on rDNA is mediated by the interaction of the A43 subunit with Rrn3

2000 • 163 citations

The Tor Pathway Regulates Gene Expression by Linking Nutrient Sensing to Histone Acetylation

2003 • 156 citations

Cell growth : control of cell size

2004 • 154 citations

Yak1p, a DYRK family kinase, translocates to the nucleus and phosphorylates yeast Pop2p in response to a glucose signal

2001 • 146 citations

Recruitment of Thr 319-phosphorylated Ndd1p to the FHA domain of Fkh2p requires Clbkinase activity: a mechanism for CLB cluster gene activation

2003 • 111 citations

Nucleocytoplasmic Distribution of Budding Yeast Protein Kinase A Regulatory Subunit Bcy1 Requires Zds1 and Is Regulated by Yak1-Dependent Phosphorylation of Its Targeting Domain

2001 • 106 citations

Suppression of yeast RNA polymerase III mutations by FHL1, a gene coding for a fork head protein involved in rRNA processing.

1994 • 104 citations

Ribosomal RNA Genes, RNA Polymerases, Nucleolar Structures, and Synthesis of rRNA in the Yeast Saccharomyces cerevisiae

2001 • 77 citations

Rpd3p Relocation Mediates a Transcriptional Response to Rapamycin in Yeast

2004 • 69 citations

Differential roles of phosphorylation in the formation of transcriptional active RNA polymerase I

2001 • 69 citations

Cell Cycle-Regulated Transcription through the FHA Domain of Fkh2p and the Coactivator Ndd1p

2003 • 65 citations

Improved Sensitivity for Phosphopeptide Mapping Using Capillary Column HPLC and Microionspray Mass Spectrometry: Comparative Phosphorylation Site Mapping from Gel-Derived Proteins

2002 • 64 citations

The IFH1 gene product interacts with a fork head protein in Saccharomyces cerevisiae

1995 • 31 citations

11 Forging the Factory: Ribosome Synthesis and Growth Control in Budding Yeast

2004 • 24 citations