Serotonin receptor changes after chronic antidepressant treatments: Ligand binding, electrophysiological, and behavioral studies

THE CATECHOLAMINE HYPOTHESIS OF AFFECTIVE DISORDERS: A REVIEW OF SUPPORTING EVIDENCE

1965 • 3,421 citations

Norepinephrine in Depressive Reactions

1965 • 1,127 citations

Long-Term Antidepressant Treatment Decreases Spiroperidol-Labeled Serotonin Receptor Binding

1980 • 840 citations

Receptor Sensitivity and the Mechanism of Action of Antidepressant Treatment

1981 • 645 citations

Discrimination of Multiple [³H]5‐Hydroxytryptamine Binding Sites by the Neuroleptic Spiperone in Rat Brain

1981 • 629 citations

Serotonergic component of neuroleptic receptors

1978 • 621 citations

Action of various antidepressant treatments reduces reactivity of noradrenergic cyclic AMP-generating system in limbic forebrain

1975 • 599 citations

Facilitation of spinal motoneurone excitability by 5-hydroxytryptamine and noradrenaline

1980 • 485 citations

Tricyclic Antidepressants: Long-Term Treatment Increases Responsivity of Rat Forebrain Neurons to Serotonin

1978 • 476 citations

Serotonergic facilitation of facial motoneuron excitation

1979 • 440 citations

Effect of electroconvulsive shock on monoaminergic receptor binding sites in rat brain

1979 • 276 citations

Excitation and depression of cortical neurones by 5‐hydroxytryptamine

1967 • 259 citations

Differential effects of electroconvulsive shock and antidepressant drugs on serotonin-2 receptors in rat brain

1981 • 237 citations

On the Slowness of Action of Tricyclic Antidepressant Drugs

1972 • 226 citations

Differential effects of antidepressant treatment on brain monoaminergic receptors

1980 • 222 citations

3H-spiroperidol labels serotonin receptors in rat cerebral cortex and hippocampus

1978 • 206 citations

Reevaluation of the indoleamine hypothesis of depression. Evidence for a reduction of functional activity of central 5-HT systems by antidepressant drugs

1979 • 181 citations

Antagonism of 5‐hydroxytryptamine by LSD 25 in the central nervous system: a possible neuronal basis for the actions of LSD 25

1970 • 163 citations

ELECTROCONVULSIVE SHOCK INCREASES THE BEHAVIOURAL RESPONSES OF RATS TO BRAIN 5‐HYDROXYTRYPTAMINE ACCUMULATION AND CENTRAL NERVOUS SYSTEM STIMULANT DRUGS

1976 • 152 citations

Brain noradrenaline depletion prevents ECS-induced enhancement of serotonin-and dopamine-mediated behaviour

1980 • 139 citations

Chronic antidepressant treatment enhances α-adrenergic and serotonergic responses in the facial nucleus

1980 • 120 citations

Enhancement of responsiveness of the central serotonergic system and serotonin-2 receptor density in rat frontal cortex by electroconvulsive treatment

1981 • 119 citations

Modifications of central 5-hydroxytryptamine binding sites in synaptic membranes from rat brain after long-term administration of tricyclic antidepressants

1979 • 119 citations

Current concepts on the mechanisms of action of antidepressant drugs

1981 • 112 citations

Pre- and postsynaptic serotonergic manipulations in an animal model of depression

1980 • 92 citations

Failure of chronic lithium treatment to block tricyclic antidepressant-induced 5-HT supersensitivity

1979 • 79 citations

Pre‐ and postsynaptic effects of zimelidine and norzimelidine on the serotoninergic system: single cell studies in the rat

1981 • 72 citations

Effect of chronic tricyclic antidepressant treatment on the serotoninergic autoreceptor

1980 • 69 citations

Theories of Biological Etiology of Affective Disorders

1970 • 68 citations

Mianserin, danitracen and amitriptyline withdrawal increases the behavioural responses of rats to L-5-HTP

1979 • 66 citations

Decrease in [3H]-serotonin binding in rat brain produced by the repeated administration of either monoamine oxidase inhibitors or centrally acting serotonin agonists

1980 • 50 citations

Decrease of [³H]5‐HT high affinity binding and 5‐HT adenylate cyclase activation after kainic acid lesion in rat brain striatum

1979 • 49 citations

Decreased spiroperidol and LSD binding in rat brain after continuous amphetamine

1980 • 49 citations

Central Antiserotonin Action of Amitriptyline

1979 • 48 citations

Towards a Biochemical Typology of Depression?

1974 • 47 citations

The responses of motoneurones to 5-hydroxytryptamine

1980 • 46 citations

Effect of single and repeated electroconvulsive shock on serotonergic system in rat brain—II behavioural studies

1980 • 43 citations

Neuroreceptors: Basic and Clinical Aspects

1982 • 39 citations

Enhancement of 5-Hydroxytryptamine-induced behavioral effects following chronic administration of antidepressant drugs

1980 • 38 citations

Intracellular studies on the effects of systemic administration of serotonin agonists on rat facial motoneurons

1982 • 36 citations

Neuroreceptors Basic and Clinical Aspects

1982 • 34 citations

Differential effects of clomipramine and clorgyline on the sensitivity of cortical neurons to serotonin: Effect of chronic treatment

1981 • 27 citations

Does [3H]spiroperidol label a 5-HT receptor in the frontal cortex of the rat?

1980 • 19 citations

Serotonin-Receptors Coupled with an Adenylate Cyclase in the Rat Brain: Non-Identity with 3H-5-HT Binding Sites

1981 • 19 citations

Treatment with trazodone plus phenoxybenzamine accelerates development of decreased type 2 serotonin binding in rat cortex

1981 • 18 citations

Biogenic amines and depression (Introduction to symposium)

1981 • 12 citations