The CD8α Gene Locus Is Regulated by the Ikaros Family of Proteins

Association of Transcriptionally Silent Genes with Ikaros Complexes at Centromeric Heterochromatin

1997 • 792 citations

Transitions in Distinct Histone H3 Methylation Patterns at the Heterochromatin Domain Boundaries

2001 • 746 citations

Selective Defects in the Development of the Fetal and Adult Lymphoid System in Mice with an Ikaros Null Mutation

1996 • 619 citations

Ikaros DNA-Binding Proteins Direct Formation of Chromatin Remodeling Complexes in Lymphocytes

1999 • 583 citations

Molecular and Cellular Events of T Cell Development

1989 • 466 citations

Locus control regions

2002 • 459 citations

Dynamic Repositioning of Genes in the Nucleus of Lymphocytes Preparing for Cell Division

1999 • 393 citations

Human CD2 3′-flanking sequences confer high-level, T cell-specific, position-independent gene expression in transgenic mice

1989 • 385 citations

Locus Control Region Function and Heterochromatin-Induced Position Effect Variegation

1996 • 373 citations

Haematopoietic cell-fate decisions, chromatin regulation and ikaros

2002 • 324 citations

Aiolos Regulates B Cell Activation and Maturation to Effector State

1998 • 313 citations

Virus Infection Leads to Localized Hyperacetylation of Histones H3 and H4 at the IFN-β Promoter

1999 • 251 citations

Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding

2000 • 250 citations

Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes

2002 • 244 citations

The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene.

1994 • 225 citations

LyF-1, a transcriptional regulator that interacts with a novel class of promoters for lymphocyte-specific genes.

1991 • 203 citations

Control of lymphocyte development by the Ikaros gene family

1999 • 157 citations

Down-regulation of TDT transcription in CD4⁺CD8⁺thymocytes by Ikaros proteins in direct competition with an Ets activator

2001 • 151 citations

Binding of Ikaros to the lambda5 promoter silences transcription through a mechanism that does not require heterochromatin formation

2001 • 148 citations

Locus control regions: overcoming heterochromatin-induced gene inactivation in mammals

1997 • 148 citations

Lyt-2 and lyt-3 antigens are on two different polypeptide subunits linked by disulfide bonds. Relationship of subunits to T cell cytolytic activity.

1981 • 142 citations

Heterochromatin protein 1 modifies mammalian PEV in a dose- and chromosomal-context- dependent manner

1999 • 124 citations

An Enhancer That Directs Lineage-Specific Expression of CD8 in Positively Selected Thymocytes and Mature T Cells

1997 • 113 citations

Multiple Developmental Stage–Specific Enhancers Regulate CD8 Expression in Developing Thymocytes and in Thymus-Independent T Cells

1998 • 107 citations

Dosage‐dependent modification of position‐effect variegation in Drosophla

1996 • 107 citations

Multiple hematopoietic defects and delayed globin switching in Ikaros null mice

2002 • 105 citations

Molecular linkage of the Ly-3 and Ly-2 genes. Requirement of Ly-2 for Ly-3 surface expression.

1988 • 101 citations

Towards an understanding of position effect variegation

1989 • 90 citations

Unconventional Potentiation of Gene Expression by Ikaros

2002 • 81 citations

A Region in the CD8 Gene Locus That Directs Expression to the Mature CD8 T Cell Subset in Transgenic Mice

1997 • 75 citations

Hierarchical Interactions of Control Elements Determine CD8α Gene Expression in Subsets of Thymocytes and Peripheral T Cells

1998 • 66 citations

The Lyt‐2, Lyt‐3 Macromolecules: Structural and Functional Studies

1982 • 64 citations

A CD8 genomic fragment that directs subset-specific expression of CD8 in transgenic mice.

1997 • 63 citations

Variegated Expression of CD8α Resulting from In Situ Deletion of Regulatory Sequences

2002 • 49 citations

Mouse Lyt-2 antigen: evidence for two heterodimers with a common subunit.

1982 • 41 citations

AP-2 and Ikaros Regulate Transcription of Human Placental Leucine Aminopeptidase/Oxytocinase Gene

2002 • 29 citations

Ikaros Chromatin Remodeling Complexes in the Control of Differentiation of the Hemo-lymphoid System

1999 • 27 citations

Ikaros, a Lymphoid-Cell-Specific Transcription Factor, Contributes to the Leukemogenic Phenotype of a Mink Cell Focus-Inducing Murine Leukemia Virus

2002 • 9 citations