Regulation of mRNA Expression in Macrophages afterYersinia enterocolitica Infection

The TNF and TNF Receptor Superfamilies

2001 • 3,533 citations

Activators and Target Genes of Rel/NF-кB Transcription Factors

2003 • 3,164 citations

Interpreting patterns of gene expression with self-organizing maps: Methods and application to hematopoietic differentiation

1999 • 2,990 citations

The Virulence Plasmid ofYersinia, an Antihost Genome

1998 • 785 citations

Krüppel-like Factors: Three Fingers in Many Pies

2001 • 600 citations

Studies on the mechanism of phagocytosis. I. Requirements for circumferential attachment of particle-bound ligands to specific receptors on the macrophage plasma membrane.

1975 • 595 citations

Phospholipase D: molecular and cell biology of a novel gene family

2000 • 495 citations

Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family

1996 • 470 citations

Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1

2001 • 466 citations

Induction of apoptosis by the transcription factor c-Jun

1997 • 421 citations

Inhibition of the Mitogen-Activated Protein Kinase Kinase Superfamily by a Yersinia Effector

1999 • 401 citations

Chk2 kinase — a busy messenger

2001 • 396 citations

Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility

2001 • 387 citations

The PTPase YopH inhibits uptake ofYersinia, tyrosine phosphorylation of p130^Casand FAK, and the associated accumulation of these proteins in peripheral focal adhesions

1997 • 373 citations

Identification of p130Cas as a substrate of Yersinia YopH (Yop51), a bacterial protein tyrosine phosphatase that translocates into mammalian cells and targets focal adhesions

1997 • 366 citations

GAP activity of the Yersinia YopE cytotoxin specifically targets the Rho pathway: a mechanism for disruption of actin microfilament structure

2000 • 334 citations

Eukaryotic initiation factor eIF2

1999 • 328 citations

Yersinia enterocolitica induces apoptosis in macrophages by a process requiring functional type III secretion and translocation mechanisms and involving YopP, presumably acting as an effector protein

1997 • 310 citations

The yopJ locus is required for Yersinia‐mediated inhibition of NF‐κB activation and cytokine expression: YopJ contains a eukaryotic SH2‐like domain that is essential for its repressive activity

1998 • 284 citations

Role of YopP in Suppression of Tumor Necrosis Factor Alpha Release by Macrophages duringYersiniaInfection

1998 • 211 citations

YopM inhibits platelet aggregation and is necessary for virulence of Yersinia pestis in mice

1990 • 195 citations

Analysis by High Density cDNA Arrays of Altered Gene Expression in Human Intestinal Epithelial Cells in Response to Infection with the Invasive Enteric BacteriaSalmonella

2000 • 191 citations

A Novel Ubiquitous Form of Munc-18 Interacts with Multiple Syntaxins.

1995 • 178 citations

Macrophage Colony-stimulating Factor Promotes Cell Survival through Akt/Protein Kinase B

1999 • 172 citations

Targeting of the Yersinia pestis YopM protein into HeLa cells and intracellular trafficking to the nucleus

1998 • 172 citations

Role of Translation Initiation Factor 2B in Control of Cell Survival by the Phosphatidylinositol 3-Kinase/Akt/Glycogen Synthase Kinase 3β Signaling Pathway

2002 • 164 citations

Suppression of T and B Lymphocyte Activation by a Yersinia pseudotuberculosis Virulence Factor, Yoph

1999 • 164 citations

The Yersinia Yop Virulon: LcrV Is Required for Extrusion of the Translocators YopB and YopD

1998 • 159 citations

The Cytotoxin YopT of Yersinia enterocoliticaInduces Modification and Cellular Redistribution of the Small GTP-binding Protein RhoA

1999 • 159 citations

Yersinia Outer Protein P of Yersinia enterocolitica Simultaneously Blocks the Nuclear Factor-κB Pathway and Exploits Lipopolysaccharide Signaling to Trigger Apoptosis in Macrophages

2001 • 156 citations

The transcriptional responses of respiratory epithelial cells toBordetella pertussisreveal host defensive and pathogen counter-defensive strategies

2000 • 154 citations

Yersinia enterocoliticaEvasion of the Host Innate Immune Response by V Antigen-Induced IL-10 Production of Macrophages Is Abrogated in IL-10-Deficient Mice

2002 • 150 citations

An immobile subset of plasma membrane CD11b/CD18 (Mac-1) is involved in phagocytosis of targets recognized by multiple receptors.

1989 • 141 citations

Induction of ARF tumor suppressor gene expression and cell cycle arrest by transcription factor DMP1

1999 • 141 citations

LcrV is a channel size‐determining component of the Yop effector translocon of Yersinia

2001 • 140 citations

Yersinia enterocolitica YopP-induced Apoptosis of Macrophages Involves the Apoptotic Signaling Cascade Upstream of Bid

2001 • 138 citations

Different mutator phenotypes in Mlh1 - versus Pms2 -deficient mice

1999 • 138 citations

RNA expression patterns change dramatically in human neutrophils exposed to bacteria

2001 • 134 citations

The Yersinia Protein Kinase A Is a Host Factor Inducible RhoA/Rac-binding Virulence Factor

2000 • 127 citations

CAF-1 and the inheritance of chromatin states: at the crossroads of DNA replication and repair

2000 • 124 citations

Monitoring Cellular Responses to Listeria monocytogenes with Oligonucleotide Arrays

2000 • 123 citations

Tyrosine-phosphorylated Plakoglobin Is Associated with Desmogleins but Not Desmoplakin after Epidermal Growth Factor Receptor Activation

2001 • 86 citations

Up-regulation of urokinase-type plasminogen activator by insulin-like growth factor-I depends upon phosphatidylinositol-3 kinase and mitogen-activated protein kinase kinase.

2001 • 84 citations

Regulation of Interferon-Induced Protein Kinase PKR: Modulation of P58^IPK Inhibitory Function by a Novel Protein, P52^rIPK

1998 • 83 citations

A Mouse Amidase Specific for N-terminal Asparagine

1996 • 81 citations

A role for IL-1α in inducing pathologic inflammation during bacterial infection

2001 • 73 citations

Two Different Signal Transduction Pathways Are Implicated in the Regulation of Initiation Factor 2B Activity in Insulin-like Growth Factor-1-stimulated Neuronal Cells

2000 • 70 citations

Trio amino-terminal guanine nucleotide exchange factor domain expression promotes actin cytoskeleton reorganization, cell migration and anchorage-independent cell growth

1999 • 66 citations

Regulators of G-Protein Signaling (RGS) 1 and 16 Are Induced in Response to Bacterial Lipopolysaccharide and Stimulate c-fos Promoter Expression

1999 • 50 citations

B-Myb prevents growth arrest associated with terminal differentiation of monocytic cells.

1996 • 42 citations

Staphylococcus aureusStimulates Urokinase‐Type Plasminogen Activator Expression by Bovine Mammary Cells

1997 • 37 citations

Platelet-derived Growth Factor Stimulation of Monocyte Chemoattractant Protein-1 Gene Expression Is Mediated by Transient Activation of the Phosphoinositide 3-Kinase Signal Transduction Pathway

1999 • 27 citations

Negative feedback regulation of activated macrophages via Fas-mediated apoptosis

2000 • 22 citations

Expression of the splice variants of the p85α regulatory subunit of phosphoinositide 3-kinase in muscle and adipose tissue of healthy subjects and type 2 diabetic patients

2001 • 20 citations

Upregulation of the gene encoding a cytoplasmic dynein intermediate chain in senescent human cells

2001 • 13 citations

Expression of the splice variants of the p85α regulatory subunit of phosphoinositide 3-kinase in muscle and adipose tissue of healthy subjects and type 2 diabetic patients

2001 • 8 citations

Preparation of RNA

1996 • 2 citations

Deleted Work

1955 • 0 citations