Role of genomic imprinting in Wilms' tumour and overgrowth disorders

Induction of apoptosis in fibroblasts by c-myc protein

1992 • 2,977 citations

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

1983 • 1,952 citations

Parental imprinting of the mouse insulin-like growth factor II gene

1991 • 1,773 citations

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

1990 • 1,300 citations

Relaxation of imprinted genes in human cancer

1993 • 792 citations

Disruption of imprinting caused by deletion of the H19 gene region in mice

1995 • 765 citations

Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour

1993 • 710 citations

Association of Wilms's Tumor with Aniridia, Hemihypertrophy and Other Congenital Malformations

1964 • 603 citations

Loss of alleles at loci on human chromosome 11 during genesis of Wilms' tumour

1984 • 538 citations

Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour

1994 • 466 citations

Uniparental paternal disomy in a genetic cancer-predisposing syndrome

1991 • 432 citations

Disruption of insulin–like growth factor 2 imprinting in Beckwith–Wiedemann syndrome

1993 • 427 citations

Somatic deletion and duplication of genes on chromosome 11 in Wilms' tumours

1984 • 426 citations

Development of homozygosity for chromosome 11p markers in Wilms' tumour

1984 • 411 citations

Aniridia-Wilms’ tumor association: evidence for specific deletion of 11p13

1979 • 404 citations

Expression of insulin-like growth factor-II transcripts in Wilms' tumour

1985 • 352 citations

Loss of a Harvey ras allele in sporadic Wilms' tumour

1984 • 336 citations

Epigenetic lesions at the H19 locus in Wilms' tumour patients

1994 • 318 citations

Parental imprinting: potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor II (Igf2) gene.

1992 • 279 citations

A model for embryonal rhabdomyosarcoma tumorigenesis that involves genome imprinting.

1989 • 260 citations

Familial predisposition to Wilms' tumour does not map to the short arm of chromosome 11

1988 • 252 citations

Insulin-like growth factor II mRNA expression in human breast cancer.

1988 • 245 citations

Lack of linkage of familial Wilms' tumour to chromosomal band 11 p13

1988 • 215 citations

Nonrandom loss of maternal chromosome 11 alleles in Wilms tumors.

1987 • 212 citations

Loss of allelic heterozygosity at a second locus on chromosome 11 in sporadic Wilms' tumor cells.

1989 • 206 citations

Differential expression of insulin-like growth factor II mRNA in human primary liver cancers, benign liver tumors, and liver cirrhosis.

1988 • 192 citations

Molecular nature of genetic changes resulting in loss of heterozygosity of chromosome 11 in Wilms' tumours

1988 • 192 citations

Insulin-like growth factor II in human adrenal pheochromocytomas and Wilms tumors: expression at the mRNA and protein level.

1987 • 191 citations

Epigenetic changes encompassing the IGF2/H19 locus associated with relaxation of IGF2 imprinting and silencing of H19 in Wilms tumor.

1995 • 147 citations

Inactivation of WT1 in nephrogenic rests, genetic precursors to Wilms' tumour

1993 • 146 citations

Expression of insulin-like growth factor-I and -II genes in human smooth muscle tumours.

1988 • 121 citations

Constitutional relaxation of insulin–like growth factor II gene imprinting associated with Wilms' tumour and gigantism

1993 • 114 citations

Trans-sensing effects from Drosophila to humans

1991 • 113 citations

Parental Imprinting of Human Chromosome Region 11p15.3-pter Involved in the Beckwith-Wiedemann Syndrome and Various Human Neoplasia

1994 • 111 citations

GENOMIC IMPRINTING AND CARCINOGENESIS

1988 • 104 citations

Insulin-like growth factor gene expression in human smooth muscle tumors.

1990 • 96 citations

Transcripts of the insulin-like growth factors I and II in human hepatoma.

1989 • 88 citations

Preferential loss of maternal alleles in sporadic Wilms' tumour.

1990 • 63 citations

Recurrent Wiedemann‐Beckwith syndrome with inversion of chromosome (11)(p11.2p15.5)

1992 • 44 citations

Insulin-like growth factor II and WT1 transcript localization in human fetal kidney and Wilms' tumor.

1993 • 25 citations

Insulin-like growth factor II messenger ribonucleic acid expression in Wilms tumor, nephrogenic rest, and kidney.

1993 • 22 citations

Enhanced expression of insulin-like growth factor II is not a necessary event in Wilms' Tumour progression

1987 • 19 citations

Genetics of Wilms' tumor: A blend of aberrant development and genomic imprinting

1994 • 18 citations