Reduced glucose metabolism enhances the glutamate-evoked release of arachidonic acid from striatal neurons

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Rapid colorimetric assay for cell growth and survival

1986 • 4,672 citations

Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization.

1994 • 2,646 citations

Glutamate and the pathophysiology of hypoxic–ischemic brain damage

1986 • 2,428 citations

The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, and Distinct Properties in the Function of the Central Nervous System

1989 • 2,203 citations

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.

1991 • 2,173 citations

cPLA2 is phosphorylated and activated by MAP kinase

1993 • 1,858 citations

Excitatory amino acid neurotoxicity and neurodegenerative disease

1990 • 1,781 citations

Calcium Fluxes, Calcium Antagonists, and Calcium-Related Pathology in Brain Ischemia, Hypoglycemia, and Spreading Depression: A Unifying Hypothesis

1989 • 1,237 citations

NMDA-dependent superoxide production and neurotoxicity

1993 • 1,188 citations

Excitatory amino acid receptors and synaptic plasticity

1990 • 872 citations

Effects of ischemia and electroconvulsive shock on free fatty acid pool in the brain

1970 • 854 citations

NMDA receptors activate the arachidonic acid cascade system in striatal neurons

1988 • 600 citations

Lactate-Supported Synaptic Function in the Rat Hippocampal Slice Preparation

1988 • 543 citations

Inhibition of phospholipase A2 by "lipocortins" and calpactins. An effect of binding to substrate phospholipids.

1987 • 534 citations

Glycogen in astrocytes: possible function as lactate supply for neighboring cells

1993 • 522 citations

PGH synthase and lipoxygenase generate superoxide in the presence of NADH or NADPH.

1986 • 489 citations

Arachidonic acid induces a prolonged inhibition of glutamate uptake into glial cells

1989 • 375 citations

Specific inhibition of pyruvate transport in rat liver mitochondria and human erythrocytes by α-cyano-4-hydroxycinnamate (Short Communication)

1974 • 372 citations

Arachidonic acid in cell signaling

1993 • 295 citations

Chronic inhibition of superoxide dismutase produces apoptotic death of spinal neurons.

1994 • 291 citations

Downregulation of Cu/Zn superoxide dismutase leads to cell death via the nitric oxide-peroxynitrite pathway

1996 • 267 citations

Mechanosensitivity of NMDA receptors in cultured mouse central neurons

1994 • 227 citations

Arachidonic acid released from striatal neurons by joint stimulation of ionotropic and metabotropic quisqualate receptors

1990 • 226 citations

Neurotransmitters Regulate Energy Metabolism in Astrocytes: Implications for the Metabolic Trafficking between Neural Cells

1993 • 212 citations

Reductions of Γ‐Aminobutyric Acid and Glutamate Uptake and (Na⁺+ K⁺)‐ATPase Activity in Brain Slices and Synaptosomes by Arachidonic Acid

1983 • 194 citations

Adenosine triphosphate depletion reverses sodium-dependent, neuronal uptake of glutamate in rat hippocampal slices

1993 • 157 citations

Changes in intracellular pH associated with glutamate excitotoxicity

1993 • 144 citations

Activation of N-methyl-D-aspartate-sensitive glutamate receptors stimulates arachidonic acid release in primary cultures of cerebellar granule cells

1988 • 137 citations

Effects of lactate and pyruvate on glucose deprivation in rat hippocampal slices

1994 • 131 citations

Lactate Metabolism and Its Effects on Glucose Metabolism in an Excised Neural Tissue

1995 • 128 citations

Uptake of l-lactate by cultured rat brain neurons

1993 • 105 citations

Lactate Utilization by Isolated Cells from Early Neonatal Rat Brain

1991 • 85 citations

A neuroglial cooperativity is required for the potentiation by 2- chloroadenosine of the muscarinic-sensitive phospholipase C in the striatum

1989 • 81 citations

Stimulation by glutamate receptors of arachidonic acid release depends on the Na+/Ca2+ exchanger in neuronal cells.

1993 • 67 citations

NMDA Receptor-Mediated Arachidonic Acid Release In Neurons: Role In Signal Transduction and Pathological Aspects

1992 • 56 citations

Effect of Glutamate and lonomycin on the Release of Arachidonic Acid, Prostaglandins and HETEs from Cultured Neurons and Astrocytes

1991 • 42 citations

Glucose Regulates Glutamate‐Evoked Arachidonic Acid Release from Cultured Striatal Neurons

1995 • 24 citations