Analysis of the beta1 and beta2 adrenoceptor interactions of the partial agonist, clenbuterol (NAB365), in the rat jugular vein and atria

SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

1959 • 3,948 citations

A MODIFICATION OF RECEPTOR THEORY

1956 • 1,126 citations

The Classification of Adrenoceptors (Adrenergic Receptors). An Evaluation from the Standpoint of Receptor Theory

1972 • 812 citations

Beta adrenergic receptor binding in membrane preparations from mammalian brain.

1976 • 576 citations

COMPARISON OF DISSOCIATION CONSTANTS AND OF RELATIVE EFFICACIES OF SELECTED AGONISTS ACTING ON PARASYMPATHETIC RECEPTORS*

1967 • 517 citations

Fundamental difference between the molecular interactions of agonists and antagonists with the β-adrenergic receptor

1979 • 259 citations

Comparison of beta adrenergic receptor subtypes in mammalian tissues.

1979 • 245 citations

Binding of (125I)iodohydroxybenzylpindolol to putative beta-adrenergic receptors of rat glioma cells and other cell clones.

1976 • 238 citations

Quantitative resolution of beta-adrenergic receptor subtypes by selective ligand binding: application of a computerized model fitting technique.

1979 • 220 citations

Dissociation constants and relative efficacies of agonists acting on alpha adrenergic receptors in rabbit aorta.

1976 • 160 citations

Coexistence of beta1 and beta2 adrenoceptors in mammalian lung: evidence from direct binding studies.

1978 • 153 citations

Classification and quantitation of β-adrenergic receptor subtypes

1980 • 122 citations

Is prenalterol (H133/80) really a selective beta 1 adrenoceptor agonist? Tissue selectivity resulting from differences in stimulus-response relationships.

1980 • 121 citations

?-Adrenoceptor blocking agents as partial agonists in isolated heart muscle: Dissociation of stimulation and blockade

1980 • 89 citations

Receptor interactions of imidazolines. I. Affinity and efficacy for alpha adrenergic receptors in rat aorta.

1979 • 88 citations

Binding of iodinated beta adrenergic antagonists to proteins derived from rat heart.

1976 • 85 citations

Pineal beta adrenergic receptor: correlation of binding of 3H-l-alprenolol with stimulation of adenylate cyclase.

1976 • 84 citations

On the Measurement of Vascular and Respiratory Smooth Muscle Responses <i>in vitro</i>

1977 • 81 citations

Identity of [3H]-dihydroalprenolol binding sites and beta-adrenergic receptors coupled with adenylate cyclase in the central nervous system: pharmacological properties, distribution and adaptive responsiveness.

1979 • 65 citations

Carazolol, an extremely potent β-adrenergic blocker: Binding to β-receptors in brain membranes

1979 • 55 citations

On spare ?-adrenoceptors for inotropic effects of catecholamines in kitten ventricle

1978 • 53 citations

On the statistics of drug-receptor constants for partial agonists.

1976 • 44 citations

Affinity Chromatography of the β‐Adrenergic Receptor from Turkey Erythrocytes

1979 • 40 citations

Beta1 and beta2 receptor mechanisms in rat jugular veins: Differences between norepinephrine and isoproterenol-induced relaxation

1978 • 39 citations

Clenbuterol, a Central β‐Adrenoceptor Agonist

1980 • 38 citations

The β adrenergic receptor of rat corpus luteum membranes

1979 • 35 citations

On equilibrium dissociation constants for complexes of drug-receptor subtypes

1982 • 34 citations

In kitten ventricular myocardium, the inotropic potency of an agonist is determined by both its intrinsic activity for the adenylyl cyclase and its affinity for the ?-adrenoceptors

1981 • 31 citations

Rat jugular vein relaxes to norepinephrine, phenylephrine and histamine.

1978 • 31 citations

Beta1- and beta2-adrenergic receptors responsible for cyclic AMP accumulation in isolated heart and lung cells.

1980 • 26 citations

Selectivity of clenbuterol (NAB 365) in guinea-pig isolated tissues containing beta-adrenoceptors.

1976 • 23 citations

Computerized graphic methods for determining dissociation constants of agonists, partial agonists, and competitive antagonists in isolated smooth muscle preparations

1980 • 23 citations

Antagonist dissociation constants and relative agonist efficacies for compounds interacting with beta-1 and beta-2 adrenergic receptors in the rat jugular vein.

1980 • 16 citations

Oral NAB 365 (clenbuterol) and terbutaline in chronic obstructive lung disease: a double-blind, two-week study.

1980 • 16 citations

Dose response relationship of clenbuterol (NAB 365) as a solution for inhalation

1979 • 14 citations

Norepinephrine, monoamine oxidase, and acetylcholinesterase in the rat jugular vein compared with other blood vessels

1979 • 8 citations

A clinical trial of oral clenbuterol (NAB 365) in chronic airways obstruction

1980 • 7 citations

Aerosolized clenbuterol (NAB 365) and salbutamol in exercise-induced asthma

1979 • 4 citations