Cytokines and Cell Adhesion Molecules in Tumor-Endothelial Cell Interaction and Metastasis

Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1).

1986 • 2,490 citations

The Immunoglobulin Superfamily—Domains for Cell Surface Recognition

1988 • 2,237 citations

Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins

1991 • 2,195 citations

The pathogenesis of cancer metastasis

1980 • 1,750 citations

Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes

1989 • 1,715 citations

Identification of an inducible endothelial-leukocyte adhesion molecule.

1987 • 1,639 citations

Circulating adhesion molecules in disease

1993 • 1,425 citations

CADHERINS: A MOLECULAR FAMILY IMPORTANT IN SELECTIVE CELL-CELL ADHESION

1990 • 1,293 citations

Leukocyte adhesion to endothelium in inflammation

1990 • 882 citations

Binding of the integrin Mac-1 (CD11b/CD18) to the third immunoglobulin-like domain of ICAM-1 (CD54) and its regulation by glycosylation

1991 • 796 citations

Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro

1991 • 729 citations

A form of circulating ICAM-1 in human serum.

1991 • 700 citations

Role of integrins and other cell adhesion molecules in tumor progression and metastasis.

1993 • 668 citations

An Inducible Endothelial Cell Surface Glycoprotein Mediates Melanoma Adhesion

1989 • 659 citations

Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist.

1990 • 569 citations

Contribution of carbohydrate antigens sialyl Lewis A and sialyl Lewis X to adhesion of human cancer cells to vascular endothelium.

1993 • 547 citations

Cytokines as communication signals between leukocytes and endothelial cells

1989 • 528 citations

Organ specificity of tumor metastasis: role of preferential adhesion, invasion and growth of malignant cells at specific secondary sites

1988 • 508 citations

Chemotactic factors regulate lectin adhesion molecule 1 (LECAM-1)-dependent neutrophil adhesion to cytokine-stimulated endothelial cells in vitro.

1991 • 439 citations

Circulating ICAM-1 isoforms: diagnostic prospects for inflammatory and immune disorders

1991 • 387 citations

Effect of venous shear stress on CD18-mediated neutrophil adhesion to cultured endothelium

1990 • 370 citations

De novo expression of intercellular-adhesion molecule 1 in melanoma correlates with increased risk of metastasis.

1989 • 367 citations

CD44 splice variants confer metastatic behavior in rats: homologous sequences are expressed in human tumor cell lines.

1991 • 347 citations

Endogenous galactoside-binding lectins: a new class of functional tumor cell surface molecules related to metastasis

1987 • 307 citations

Interleukin 1 increases the binding of human B and T lymphocytes to endothelial cell monolayers.

1986 • 296 citations

Integrins and tumor cell dissemination.

1989 • 294 citations

Differential expression of intercellular adhesion molecule 1 in primary and metastatic melanoma lesions.

1990 • 274 citations

Interactions of tumor cells with vascular endothelial cell monolayers: a model for metastatic invasion.

1979 • 270 citations

The CD2-LFA-3 and LFA-1-ICAM pathways: relevance to T-cell recognition

1989 • 269 citations

Selectins: Novel Receptors that Mediate Leukocyte Adhesion During Inflammation

1991 • 264 citations

Specificity of adhesion between murine tumor cells and capillary endothelium: an in vitro correlate of preferential metastasis in vivo.

1987 • 250 citations

American Association of Pathologists president's address. New roles for the endothelium in inflammation and immunity.

1987 • 232 citations

Rolling and adhesion of human tumor cells on vascular endothelium under physiological flow conditions.

1993 • 216 citations

Interleukin 1-induced augmentation of experimental metastases from a human melanoma in nude mice.

1990 • 199 citations

Enhancement of experimental metastasis by tumor necrosis factor.

1993 • 198 citations

Serum levels of circulating intercellular adhesion molecule 1 in human malignant melanoma.

1991 • 173 citations

Morphological study of the interaction of intravascular tumor cells with endothelial cells and subendothelial matrix.

1988 • 158 citations

Laminin receptors and laminin-binding proteins during tumor invasion and metastasis.

1993 • 154 citations

Cells secreting tumour necrosis factor show enhanced metastasis in nude mice

1990 • 154 citations

Interleukin 1 promotes tumor cell adhesion to cultured human endothelial cells.

1988 • 150 citations

Interactions between cancer cells and the microvasculature: a rate-regulator for metastasis

1989 • 144 citations

Tumor cell-endothelial interactions. Increased adhesion of human melanoma cells to activated vascular endothelium.

1988 • 137 citations

Mediation of lung metastasis of murine melanomas by a lung-specific endothelial cell adhesion molecule.

1991 • 133 citations

Tumor Cell Adhesion to Endothelial Cells: Endothelial Leukocyte Adhesion Molecule-1 as an Inducible Adhesive Receptor Specific for Colon Carcinoma Cells

1991 • 129 citations

Roll, roll, roll your leucocyte gently down the vein.

1992 • 117 citations

Microvascular endothelial cell heterogeneity: Interactions with leukocytes and tumor cells

1990 • 104 citations

Cytokine-induced enhancement of ICAM-1 expression results in increased vulnerability of tumor cells to monocyte-mediated lysis.

1991 • 103 citations

Soluble intercellular adhesion molecule 1 is released by human melanoma cells and is associated with tumor growth in nude mice.

1992 • 102 citations

Heterogeneity in human melanoma cell adhesion to cytokine activated endothelial cells correlates with VLA-4 expression.

1991 • 93 citations

Endothelial leukocyte adhesion molecule-1-dependent adhesion of colon carcinoma cells to vascular endothelium is inhibited by an antibody to Lewis fucosylated type I carbohydrate chain.

1992 • 91 citations

Effect of Interleukin-1-beta on Metastasis Formation in Different Tumor Systems

1991 • 86 citations

Interleukin 1 receptor antagonist inhibits the augmentation of metastasis induced by interleukin 1 or lipopolysaccharide in a human melanoma/nude mouse system.

1993 • 80 citations

Interleukin-1 increases tumor cell adhesion to endothelial cells through an RGD dependent mechanism: in vitro and in vivo studies

1990 • 61 citations

De Novo expression of intercellular adhesion molecule 1(ICAM‐1, CD54) in pancreas cancer

1993 • 46 citations

Effect of IL‐1 on experimental bone/bone‐marrow metastases

1992 • 42 citations

Interleukin 1-induced cancer cell/endothelial cell adhesion in vitro and its relationship to metastasis in vivo: role of vessel wall 13-HODE synthesis and integrin expression

1993 • 39 citations