Tracking the clonal origin of lethal prostate cancer

Cancer statistics, 2012

2012 • 10,655 citations

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

2012 • 7,135 citations

The mutational landscape of lethal castration-resistant prostate cancer

2012 • 2,378 citations

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

2010 • 2,359 citations

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

2012 • 1,931 citations

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

2005 • 1,893 citations

The principles and practice of medicine

1938 • 1,719 citations

Radical Prostatectomy versus Observation for Localized Prostate Cancer

2012 • 1,692 citations

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

2012 • 1,433 citations

The genomic complexity of primary human prostate cancer

2011 • 1,209 citations

Human Genome Sequencing Using Unchained Base Reads on Self-Assembling DNA Nanoarrays

2009 • 1,207 citations

Genome remodelling in a basal-like breast cancer metastasis and xenograft

2010 • 1,138 citations

Reciprocal Feedback Regulation of PI3K and Androgen Receptor Signaling in PTEN-Deficient Prostate Cancer

2011 • 1,125 citations

Altered Telomeres in Tumors with ATRX and DAXX Mutations

2011 • 962 citations

PTEN Protein Loss by Immunostaining: Analytic Validation and Prognostic Indicator for a High Risk Surgical Cohort of Prostate Cancer Patients

2011 • 336 citations

Do Adenocarcinomas of the Prostate With Gleason Score (GS)≤6 Have the Potential to Metastasize to Lymph Nodes?

2012 • 322 citations

Heterogeneity of Gleason grade in multifocal adenocarcinoma of the prostate

2004 • 296 citations

Characterization of TMPRSS2-ETS Gene Aberrations in Androgen-Independent Metastatic Prostate Cancer

2008 • 271 citations

Molecular classification of prostate cancer using curated expression signatures

2011 • 180 citations

Exome Sequencing of Prostate Cancer Supports the Hypothesis of Independent Tumour Origins

2012 • 153 citations

Complex patterns of ETS gene alteration arise during cancer development in the human prostate

2007 • 149 citations

Phase I/II Trial of an Allogeneic Cellular Immunotherapy in Hormone-Naïve Prostate Cancer

2006 • 133 citations

Natural History of Pathologically Organ-Confined (pT2), Gleason Score 6 or Less, Prostate Cancer After Radical Prostatectomy

2008 • 80 citations

Genome sequencing and cancer

2012 • 68 citations

Prostate Cancer Screening—The Evidence, the Recommendations, and the Clinical Implications

2011 • 43 citations

Expression of ABH Blood Group Isoantigen as a Prognostic Factor in Transitional Cell Bladder Carcinoma

1988 • 32 citations