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c-erbB-2 amplification in breast cancer: Detection in formalin-fixed, paraffin-embedded tissue by in situ hybridization☆

Data up to Jan 2025

Published1994
Citations18
References37

Total Citations Per Year

Abstract

References (37)

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

Studies of the HER-2/ neu Proto-Oncogene in Human Breast and Ovarian Cancer

1989 • 6,734 citations

pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long‐term follow‐up

1991 • 5,979 citations

Linkage of Early-Onset Familial Breast Cancer to Chromosome 17q21

1990 • 2,505 citations

Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with neu Oncogene

1985 • 1,804 citations

Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor

1986 • 1,226 citations

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

1988 • 1,160 citations

Neu-Protein Overexpression in Breast Cancer

1988 • 860 citations

Prognostic importance of c-erbB-2 expression in breast cancer. International (Ludwig) Breast Cancer Study Group.

1992 • 855 citations

Overexpression of HER-2/neu is associated with poor survival in advanced epithelial ovarian cancer.

1990 • 763 citations

HER-2/neu oncogene protein and prognosis in breast cancer.

1989 • 579 citations

ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization.

1992 • 542 citations

HER-2/neu in node-negative breast cancer: prognostic significance of overexpression influenced by the presence of in situ carcinoma.

1992 • 466 citations

Overexpression of HER-2/neu and its relationship with other prognostic factors change during the progression of in situ to invasive breast cancer

1992 • 415 citations

Description of an In Situ Hybridization Methodology for Detection of Epstein-Barr Virus RNA in Paraffin-Embedded Tissues, with a Survey of Normal and Neoplastic Tissues

1992 • 337 citations

Comparative genomic hybridization: a rapid new method for detecting and mapping DNA amplification in tumors.

1993 • 232 citations

Structure and expression of c‐erbB‐2 and EGF receptor genes in inflammatory and non‐inflammatory breast cancer: Prognostic significance

1989 • 197 citations

c-erbB-2 expression in benign and malignant breast disease

1988 • 190 citations

Immunohistochemical demonstration of c-erbB-2 protein in mammary ductal carcinoma in situ

1990 • 163 citations

Overexpression of erbB-2 or EGF receptor proteins present in early stage mammary carcinoma is detected simultaneously in matched primary tumors and regional metastases.

1989 • 160 citations

Overexpression of either c-myc or c-erbB-2/neu proto-oncogenes in human breast carcinomas: correlation with poor prognosis.

1988 • 149 citations

Increased erbB-2 gene copies and expression in multiple stages of breast cancer.

1990 • 134 citations

Overexpression of the c-erbB-2 oncoprotein: Why does this occur more frequently in ductal carcinoma in situ than in invasive mammary carcinoma and is this of prognostic significance?

1992 • 131 citations

Immunohistochemical distribution of c‐erbB‐2 in infiltrating and in situ breast cancer

1988 • 130 citations

Immunohistochemical distribution of c‐erbB‐2 in in situ breast carcinoma—a detailed morphological analysis

1990 • 127 citations

Immunohistochemical evaluation of c-erbB-2 oncogene expression in ductal carcinoma in situ and atypical ductal hyperplasia of the breast.

1990 • 122 citations

c-erbB-2 overexpression and histological type of in situ and invasive breast carcinoma.

1992 • 102 citations

C-ERBB-2 oncogens protein inIn situ and invasive lobular breast neoplasia

1991 • 85 citations

c-erbB-2 expression in different histological types of invasive breast carcinoma.

1991 • 83 citations

Immunohistochemical localization of c-erbB-2 in human breast carcinomas

1987 • 74 citations

Human breast cancer: identification of populations with a high risk of early relapse in relation to both oestrogen receptor status and c-erbB-2 overexpression

1990 • 56 citations

An immunohistochemical and in situ hybridization study of c‐myc and c‐erbB‐2 expression in primary human breast carcinomas

1989 • 47 citations

In situ distribution of oncogene products and growth factor receptors in breast carcinoma: c-erbB-2 oncoprotein, EGFr, and PDGFr-β-subunit

1990 • 28 citations

What's New in Breast Cancer?

1993 • 27 citations

Gene Amplification and Expression of the <i>neu </i>(c-erbB-2) Sequence in Human Mammary Carcinoma

1988 • 27 citations

c-erbB-2 Amplification and overexpression in breast cancer: evaluation and comparison of southern BLOT, SLOT BLOT, ELISA and immunohistochemistry

1993 • 21 citations

Detection of c-erbB-2 amplification in breast cancer by in situ hybridization

1993 • 7 citations

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