Roles of Cytochromes P450 1A2 and 3A4 in the Oxidation of Estradiol and Estrone in Human Liver Microsomes

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 3,435 citations

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature

1996 • 2,895 citations

The Human Hepatic Cytochromes P450 Involved in Drug Metabolism

1992 • 932 citations

Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism.

1986 • 734 citations

Molecular Mechanisms of Estrogen Carcinogenesis

1996 • 659 citations

Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits, and humans using immunochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresis

1982 • 422 citations

Principles and methods of toxicology

1995 • 407 citations

Purification and characterization of the human liver cytochromes P-450 involved in debrisoquine 4-hydroxylation and phenacetin O-deethylation, two prototypes for genetic polymorphism in oxidative drug metabolism.

1985 • 319 citations

Characterization of Human Microsomal Cytochrome P-450 Enzymes

1989 • 244 citations

17β-Estradiol hydroxylation catalyzed by human cytochrome P450 1A1: A comparison of the activities induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in MCF-7 cells with those from heterologous expression of the cDNA

1992 • 242 citations

Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics

1992 • 228 citations

Upregulation of Estradiol C16 -hydroxylation in Human Breast Tissue: a Potential Biomarker of Breast Cancer Risk

1993 • 149 citations

Relationship between CYP2C9 and 2C19 genotypes and tolbutamide methyl hydroxylation and S-mephenytoin 4???-hydroxylation activities in livers of Japanese and Caucasian populations

1997 • 134 citations

Reconstitution of Recombinant Cytochrome P450 2C10(2C9) and Comparison with Cytochrome P450 3A4 and Other Forms: Effects of Cytochrome P450–P450 and Cytochrome P450–b5Interactions

1997 • 124 citations

Interindividual variability in catalytic activity and immunoreactivity of three major human liver cytochrome P450 isozymes

1996 • 81 citations

Metabolic activation of environmental carcinogens and mutagens by human liver microsomes

1988 • 52 citations

Progesterone metabolism in hepatic microsomes. Effect of the cytochrome P-450 inhibitor, ketoconazole, and the NADPH 5 alpha-reductase inhibitor, 4-MA, upon the metabolic profile in human, monkey, dog, and rat.

1990 • 30 citations